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2007 대한임상노인의학회 추계학술대회 Cardiac Ausculation in the Elderly 박 성 하 신촌세브란스병원 심장혈관병원 심장내과 Evaluating pulsation Anatomy Surface projection of the Heart and Great Vessels Superior vena cava Rt. pulmonary artery Right atrium Right ventricle Aorta Lt. pulmonary artery Pulmonary artery Left ventricle Apical impulse femoral carotid Dorsalis pedis Post. tibial Arterial Pulse Arterial Pulse - 287 - 2007 대한임상노인의학회 추계학술대회 Auscultation Palpation – Thrill Systolic thrill - AS: Rt 2nd, 3RD ICS, suprasternal notch, jugular Maximal intensity - VSD: Lt 4th, 5th ICS and radiation of - PS, ASD: Lt 2nd ICS - MR: apex to left axilla six isolated sys. Diastolic thrill murmurs - MS: apex - AR, Ascending aorta dissection: Rt parasternal border Continuous thrill - PDA - AV fistula HighHigh- and LowLow-frequency Sounds Explained Auscultation Cardiac apex Mid-sternal edge Left lateral decubitus position Leans forward with breath held in full respiration Timing of Cardiac Sounds Physiology • Events in Cardiac Cycle S1(first heart sound) : MV closure - 288 - 박성하: Cardiac Ausculation in the Elderly Physiology • Events in Cardiac Cycle Ej (ejection sound) Physiology • Events in Cardiac Cycle : AV opening S2 (second heart sound) : AV closure Physiology Physiology • Events in Cardiac Cycle OS (Opening snap) : MV opening • Events in Cardiac Cycle S3 (third heart sound) : LA Î LV diastolic filling Physiology Auscultation • Events in Cardiac Cycle Rate & regularity Heart sounds – especially intensity and quality of S2, as well as extra sounds (S3, S4) Murmurs Clicks Rubs S4 (fourth heart sound) : Atrial contraction - 289 - 2007 대한임상노인의학회 추계학술대회 Systolic Murmur - Intensity of murmurs ejection vs regurgitant I II III IV V VI barely audible Regurgitant: Pansystolic murmur occurs with S1 Soft, but easily audible MR Moderately loud S1 Louder, with a thrill Audible with stethoscope barely on chest S1 AS Audible with stethoscope off chest S1 Systolic Murmurs S2 Ejection: Mid-systolic murmur occurs after S1 S2 S1 Selected causes of systolic murmur 1. 2. 3. 4. 5. 6. 7. 8. Abnormal cardiac structure Aortic stenosis Hypertrophic cardiomyopathy Mitral regurgitation Mitral valve prolapse Ventricular septal defect Pulmonic stenosis Tricuspid regurgitation Atrial septal defect 1. 2. 3. 4. Normal cardiac structure, increased flow Anemia Thyrotoxicosis Sepsis Renal failure with volume overload How to rule out pathologic systolic murmur Prevalence of systolic murmur in unreferred young adults: 5-52% Prevalence of systolic murmur in the elderly: 29-60% Prevalence of systolic murmur in pregnancy: 90-94% Prevalence of valvular heart disease in patients referred for murmurs: < 50% 98% of patients < 50 years of age with systolic m ≤ grade 2/6 had innocent murmurs > 2/6 grade systolic m and abnormal EKG are independent predictors of significant valvular heart disease in 224 consecutive patients with systolic murmur Movahed MR et al. Echocardiography 2007;24:447-451 Etchells E et al. JAMA 1997;277:564-571 - 290 - Reichlin S et al. Am J Emerg Med 2004;22:71-75 박성하: Cardiac Ausculation in the Elderly Criteria of pathologic murmur Aortic stenosis > 2/6 grade systolic murmur with maximal intensity at RUSB 2nd ICS Abnormal EKG Murmur or thrill over right carotid, clavicular area Prolonged, blunted cardiac upstroke Soft or absent S2 Ejection: Mid-systolic murmur occurs after S1 AS S1 Das P et al. Q J Med 2000;93:685-688 Integrating pulse with sounds and murmur Hemodynamics and flow Inspection: Pressures: Carotid pulse for timing LV-Ao pressure gradient throughout systole – murmur occurs w/ upstroke – – – – murmur occurs w/ upstroke sound occurs near peak murmur is systolic sound is S2 CW Doppler: high velocity outflow – reaches peak of 5 m/sec – est. 100 mmHg gradient Compare with normal carotid – normal peaks well before S2 – carotid peak is delayed – carotid peak is weak Severe AS: LV pressure rises – increases LV-Ao gradient murmur peaks later Auscultation: murmur is midsystolic murmur ends before S2 Ejection sound at 3RICS Chronic MR Mitral regurgitation Inspection: apex beat displaced to 7LICS outward excursion of stethoscope head during systole Auscultation: blowing murmur with outward excursion of stethoscope a thudding sound with inward return of stethoscope Regurgitant: Pansystolic murmur occurs with S1 murmur is holosystolic – heard best over LV MR sound is S3 S1 S2 S1 - 291 - S2 S1 2007 대한임상노인의학회 추계학술대회 Acute MR Patient 07 Inspection: rocking stethoscope by LV left subcostal heave (RV) Auscultation: Early systolic murmur begins with sharp S1 Isolated, clear S2 S3 rumble Mitral valve prolapse Hemodynamics of Acute and Chronic Normal: S1, S2, no murmurs Mitral valve prolapse: midsystolic click, possible late systolic murmur of MR Acute MR: here, from chordal rupture loud S1, initiates explosive systolic murmur S3 with mid-diastolic murmur MVP Compensation: S1 click S2 S1 increased compliance of LA, LV blowing holosystolic murmur mid-diastolic rumble Ventricular Septal defect Tricuspid regurgitation Variation of pansystolic murmur according to respiration (Carvallo’s sign) - 292 - 박성하: Cardiac Ausculation in the Elderly Diastolic Murmurs Diastolic Murmur – Early and mid. Rumbling murmur : MS S2 S1 S1 Early-diastolic murmur : AR S2 S1 S1 Mitral Stenosis Mitral stenosis Inspection: subtle monophasic pulses in suprasternal notch (carotid) conspicuous biphasic pulses (JVP), are a-wave dominant stethoscope displays RV lift during systole Auscultation: MS loud S1 (coincides w/ a-wave) S1 Patient 05 S2 OS S1 “split” S2 is fixed – S2 – opening snap (OS) Compare sounds with split S2, S3 Listening at Base: abnormally loud S1 at base shorter S2-OS interval indicates severe MS Listening at Apex: crescendo, presystolic murmur loud S1 S2, OS mid-diastolic murmur Inspection: JVP is a-wave dominant a-wave occurs with loud S1 - 293 - 2007 대한임상노인의학회 추계학술대회 Add / Remove sounds Hemodynamic effects of heart rate 80 bpm: Loud S1: tachycardia exacerbates LA emptying dysfunction loud S1 loud MDM, PSM elevated LA pressure mitral valve closes later, and more loudly than normal Opening Snap: 110 bpm: mitral valve opens earlier than normal ( LA pressure) fused leaflets abruptly halt mitral valve opening, causing OS loud murmur was thought to be systolic by house staff murmur ends with loud S1 mid-diastolic murmur 66 bpm: each component can be heard loud S1, S2/OS, MDM, PSM Mid-diastolic murmur: corresponds w/ LA-LV gradient Acute severe, rapid heart rate Aortic Regurgitation Examination at 3LICS bounding (Corrigan's) pulse to-fro systolic & diastolic murmur – harsh midsystolic murmur – abbreviated early diastolic murmur initiated by a loud S2 Inspection of nailbed light compression of fingernail blanching & blushing of nailbed AR S1 Patient 02 S2 S1 Well-tolerated aortic regurgitation Inspection: Carotid pulse – visible at suprasternal notch – normal upstroke – upstroke occurs near S1 Jugular venous pulse – visible at right supraclavicular fossa – biphasic – displaces neck chain Auscultation: EDM is long (holodiastolic) sounds like whispered “R” longer murmur = better tolerated - 294 - 박성하: Cardiac Ausculation in the Elderly Chronic vs. Acute Aortic Regurgitation Aortic Regurgitation Inspection: Chronic: bounding (Corrigan’s) pulse at Base: – MSM (Ao outflow) – EDM (Ao regurgitation) head bobbing (Musset’s sign) compare with normal carotid at Apex: – Austin Flint (mitral inflow) – “split” S1 (S1 + ejection sound) Auscultation: “To-fro” murmur Acute: – Midsystolic murmur – Early diastolic murmur at Base: – MSM (Ao outflow) – EDM is abbreviated 3RICS – “To-FRO” at Apex: – Austin Flint (mitral inflow) – absent S1 (ejection sound only) 2RICS – “TO-fro” Third Heart Sound S3 Physiology • Events in Cardiac Cycle S3 (third heart sound) : LA Î LV diastolic filling Fourth Heart Sound S4 Gallop Physiology • Events in Cardiac Cycle S4 (fourth heart sound) : Atrial contraction - 295 - 2007 대한임상노인의학회 추계학술대회 Splitting of the Second Sound S3 and S4 Associated with abnormal S3,S4: Summation gallop Fixed S2 splitting with respiration Inspiration Atrial septal defect Expiration Venous return Venous return S1 S1 A2 P2 A2 P2 Inspiration Venous return In ASD LÆR shunt Fixed S2 split!! Expiration LÆR shunt Venous return Mid systolic murmur and S2 split at 2nd pulmonic area Diastolic murmur: Austin Flint Listening at apex: tachycardia (110 bpm) dynamic, displaced apical impulse absence of S1 triple cadence consisting of – midsystolic murmur – S2 initiating a brief early diastolic murmur – mid-diastolic murmur superimposed on the early diastolic murmur, (to-froFRO) - 296 - 박성하: Cardiac Ausculation in the Elderly Summary of Heart Sounds & Murmurs - 297 -