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Chapter 5 Lecture Concepts of Genetics Tenth Edition Chromosome Mapping in Eukaryotes Copyright © 2009 Pearson Education, Inc. 5.1 Genes Linked on the Same Chromosome Segregate Together Copyright © 2009 Pearson Education, Inc. Copyright © 2009 Pearson Education, Inc. Figure 5.1 Copyright © 2009 Pearson Education, Inc. Figure 5.1a Copyright © 2009 Pearson Education, Inc. Figure 5.1b Copyright © 2009 Pearson Education, Inc. Figure 5.1c 5.1 Genes Linked on the Same Chromosome Segregate Together 5.1.1 The Linkage Ratio Copyright © 2009 Pearson Education, Inc. Copyright © 2009 Pearson Education, Inc. Figure 5.2 Copyright © 2009 Pearson Education, Inc. Figure 5.2-01 Copyright © 2009 Pearson Education, Inc. Figure 5.2ab Copyright © 2009 Pearson Education, Inc. Figure 5.2a Copyright © 2009 Pearson Education, Inc. Figure 5.2b 5.2 Crossing Over Serves as the Basis of Determining the Distance between Genes in Chromosome Mapping 5.2.1 Morgan and Crossing Over Copyright © 2009 Pearson Education, Inc. Copyright © 2009 Pearson Education, Inc. Figure 5.3 5.2 Crossing Over Serves as the Basis of Determining the Distance between Genes in Chromosome Mapping 5.2.2 Sturtevant and Mapping Copyright © 2009 Pearson Education, Inc. Copyright © 2009 Pearson Education, Inc. Figure 5.4 5.2 Crossing Over Serves as the Basis of Determining the Distance between Genes during Chromosome Mapping 5.2.3 Single Crossovers Copyright © 2009 Pearson Education, Inc. Copyright © 2009 Pearson Education, Inc. Figure 5.5 Copyright © 2009 Pearson Education, Inc. Figure 5.6 5.3 Determining the Gene Sequence in Mapping Requires the Analysis of Multiple Crossovers 5.3.1 Multiple Exchanges Copyright © 2009 Pearson Education, Inc. Copyright © 2009 Pearson Education, Inc. Figure 5.7ab Copyright © 2009 Pearson Education, Inc. Figure 5.7a 5.3 Determining the Gene Sequence in Mapping Requires the Analysis of Multiple Crossovers 5.3.2 Three-Point Mapping in Drosophila Copyright © 2009 Pearson Education, Inc. Copyright © 2009 Pearson Education, Inc. Figure 5.8 5.3 Determining the Gene Sequence in Mapping Requires the Analysis of Multiple Crossovers 5.3.3 Determining the Gene Sequence 5.3.3.1 Method I 5.3.3.2 Method II Copyright © 2009 Pearson Education, Inc. Copyright © 2009 Pearson Education, Inc. Figure 5.9 5.3 Determining the Gene Sequence in Mapping Requires the Analysis of Multiple Crossovers 5.3.4 A Mapping Problem in Maize Copyright © 2009 Pearson Education, Inc. Copyright © 2009 Pearson Education, Inc. Figure 5.10 Copyright © 2009 Pearson Education, Inc. Figure 5.10a Copyright © 2009 Pearson Education, Inc. Figure 5.10b Copyright © 2009 Pearson Education, Inc. Figure 5.11 Interference Affects the Recovery of Multiple Exchanges Copyright © 2009 Pearson Education, Inc. 5.4 As the Distance Between Two Genes Increases, the Results of Mapping Experiments Become Less Accurate Copyright © 2009 Pearson Education, Inc. Copyright © 2009 Pearson Education, Inc. RF= 0.5(1-e-m) x 100 m is the mean number of crossovers Copyright © 2009 Pearson Education, Inc. Figure 5-12 Copyright © 2006 Pearson Prentice Hall, Inc. 5.5 Drosophila Genes Have Been Extensively Mapped Actually, the Drosophila genome has been sequenced Copyright © 2009 Pearson Education, Inc. Copyright © 2009 Pearson Education, Inc. Figure 5.13 5.6 Lod Score Analysis and Somatic Cell Hybridization Were Historically Important in Creating Human Chromosome Maps Copyright © 2009 Pearson Education, Inc. Copyright © 2009 Pearson Education, Inc. Figure 5.14 Copyright © 2009 Pearson Education, Inc. 5.7 Chromosome Mapping is Now Possible Using DNA Markers and Annotated Computer Databases Copyright © 2009 Pearson Education, Inc. 5.8 Crossing Over Involves a Physical Exchange between Chromatids Copyright © 2009 Pearson Education, Inc. Copyright © 2009 Pearson Education, Inc. Figure 5.15 Recombination Occurs between Mitotic Chromosomes Copyright © 2009 Pearson Education, Inc. Copyright © 2009 Pearson Education, Inc. 5.9 Exchanges Also Occur between Sister Chromatids Copyright © 2009 Pearson Education, Inc. Copyright © 2009 Pearson Education, Inc. Figure 5.16 5.11 Did Mendel Encounter Linkage? (maybe) I won’t tell Copyright © 2009 Pearson Education, Inc.
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