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NEUROLOGICAL Class Drug Formulation Dose Avail. Indications Contraindications Warning Hypnotics Zopiclone 3.75mg tab 3.75-15mg nocte < 4 weeks only Hypnotics Zopiclone 7.5mg tab 3.75-15mg nocte < 4 weeks only Hypnotics Temazepam 10mg tab 10-20mg nocte Hypnotics Temazepam 20mg tab 10-20mg nocte Hypnotics Temazepam 10mg/5ml oral soln 10-20mg nocte Anxiolytics Diazepam 2mg tab 2-10mg tds < 4 weeks only Anxiolytics Diazepam 5mg tab 2-10mg tds < 4 weeks only Anxiolytics Diazepam 2mg/5ml oral soln 2-10mg tds < 4 weeks only Antipsychotics Chlorpromazine 25mg tab 25-100mg tds Severe liver /renal /CVD Avoid in Parkinsons /Elderly Antipsychotics Chlorpromazine 50mg tab 50-100mg tds Severe liver /renal /CVD Avoid in Parkinsons /Elderly Antipsychotics Chlorpromazine 100mg tab 100mg tds Severe liver /renal /CVD Avoid in Parkinsons /Elderly Antipsychotics Chlorpromazine 25mg/5ml oral soln 25-100mg tds Severe liver /renal /CVD Avoid in Parkinsons /Elderly Antipsychotics Chlorpromazine 100mg/5ml oral soln 50-100mg tds Severe liver /renal /CVD Avoid in Parkinsons /Elderly Antipsychotics Chlorpromazine 25mg/ml injection 25-100mg stat Severe liver /renal /CVD Avoid in Parkinsons /Elderly Antipsychotics Haloperidol 0.5mg caps/tabs 0.5-5mg tds Parkinson's disease /Lewy body dementia Prolongs QT interval Antipsychotics Haloperidol 1.5mg caps/tabs 1.5-5mg tds Parkinson's disease /Lewy body dementia Prolongs QT interval Antipsychotics Haloperidol 5mg caps/tabs 5mg tds Parkinson's disease /Lewy body dementia Prolongs QT interval Antipsychotics Haloperidol 1mg/ml oral soln 1-5mg tds Parkinson's disease /Lewy body dementia Prolongs QT interval Antipsychotics Haloperidol 5mg/ml injection 1-5mg IMI stat Parkinson's disease /Lewy body dementia Prolongs QT interval Antidepressants Fluoxetine 20mg caps 20-60mg daily Also OCD indication Caution in diabetes Antidepressants Fluoxetine 20mg disp tabs 20-60mg daily Also OCD indication Caution in diabetes Antidepressants Sertraline 50mg tab 50-100mg daily Good option in elderly + CVD Antidepressants Sertraline 100mg tab 50-100mg daily Good option in elderly + CVD Antidepressants Mirtazapine 15mg tab 15-45mg nocte Good for hypnotic effect if needed Causes weight gain and sedation Antidepressants Mirtazapine 30mg tab 15-45mg nocte Good for hypnotic effect if needed Causes weight gain and sedation Antidepressants Mirtazapine 45mg tab 15-45mg nocte Good for hypnotic effect if needed Causes weight gain and sedation Antidepressants Mirtazapine 15mg disp tab 15-45mg nocte Good for hypnotic effect if needed Causes weight gain and sedation Antidepressants Mirtazapine 30mg disp tab 15-45mg nocte Good for hypnotic effect if needed Causes weight gain and sedation Antidepressants Mirtazapine 45mg disp tab 15-45mg nocte Good for hypnotic effect if needed Causes weight gain and sedation Antidepressants Venlafaxine 37.5mg tab 75mg-375mg daily Also GAD indication Antidepressants Venlafaxine 75mg tab 75mg-375mg daily Also GAD indication Antidepressants Venlafaxine 75mg MR tab 75mg-375mg daily Also GAD indication Antidepressants Venlafaxine 150mg MR tab 75mg-375mg daily Also GAD indication Antidepressants Duloxetine 30mg caps (Cymbalta) 30-60mg daily Also GAD + diabetic neuropathy Antidepressants Duloxetine 60mg caps (Cymbalta) 30-60mg daily Also GAD + diabetic neuropathy Panic disorder /PTSD /Social anxiety Sertraline 50mg tab 25-200mg daily Also OCD indication Panic disorder /PTSD /Social anxiety Sertraline 100mg tab 25-200mg daily Also OCD indication Panic disorder Citalopram 10mg 10-40mg daily Panic disorder Citalopram 20mg 10-40mg daily Panic disorder Citalopram 40mg 10-40mg daily Panic disorder Citalopram 40mg/ml oral drops 10-40mg daily GAD Paroxetine 20mg tab 20-30mg daily GAD Paroxetine 30mg tab 20-30mg daily Agitation in Elderly Trazedone 50mg caps 100-300mg nocte or div. bd Sedation effect Agitation in Elderly Trazedone 100mg caps 100-300mg nocte or div. bd Sedation effect Agitation in Elderly Trazedone 150mg caps 100-300mg nocte or div. bd Sedation effect Agitation in Elderly Trazedone 50mg/5ml liquid 100-300mg nocte or div. bd CNS stimulants /ADHD Methylphenidate* 5mg tab 5-60mg mane or div. bd Specialist clinic to initiate CNS stimulants /ADHD Methylphenidate* 10mg tab 5-60mg mane or div. bd Specialist clinic to initiate CNS stimulants /ADHD Methylphenidate* 20mg tab 5-60mg mane or div. bd Specialist clinic to initiate CNS stimulants /ADHD Xaggitin XL* 18mg MR caps 18-54mg daily Specialist clinic to initiate CNS stimulants /ADHD Xaggitin XL* 24mg MR caps 18-54mg daily Specialist clinic to initiate CNS stimulants /ADHD Xaggitin XL* 36mg MR caps 18-54mg daily Specialist clinic to initiate CNS stimulants /ADHD Xaggitin XL* 54mg MR caps 18-54mg daily Specialist clinic to initiate CNS stimulants /ADHD Atomoxetine* 10mg caps 20-120mg mane or div. bd Specialist clinic to initiate CNS stimulants /ADHD Atomoxetine* 18mg caps 20-120mg mane or div. bd Specialist clinic to initiate CNS stimulants /ADHD Atomoxetine* 25mg caps 20-120mg mane or div. bd Specialist clinic to initiate CNS stimulants /ADHD Atomoxetine* 40mg caps 20-120mg mane or div. bd Specialist clinic to initiate CNS stimulants /ADHD Atomoxetine* 60mg caps 20-120mg mane or div. bd Specialist clinic to initiate CNS stimulants /ADHD Atomoxetine* 80mg caps 20-120mg mane or div. bd Specialist clinic to initiate CNS stimulants /ADHD Atomoxetine* 100mg caps 20-120mg mane or div. bd Specialist clinic to initiate CNS stimulants /ADHD Atomoxetine* 4mg/ml oral soln 20-120mg mane or div. bd Specialist clinic to initiate Anti-obesity drugs Orlistat 120mg caps 120mg before each meal Anti-vertigo Betahistine 8mg tabs 8-16mg tds Meniere's disease Anti-vertigo Betahistine 16mg tabs 8-16mg tds Meniere's disease Anti-nausea /Anti-vertigo Cinnarizine 15mg tabs 2 tabs tds Anti-nausea /Anti-vertigo Cyclizine 50mg tabs 50mg tds Anti-nausea /Anti-vertigo Cyclizine 50mg/ml injection 50mg IMI/IVI 8hrly Anti-nausea /Anti-vertigo Prochlorperazine 5mg tab 5-10mg tds (20mg stat) Also for intractable hiccups Anti-nausea /Anti-vertigo Prochlorperazine 3mg buccal tab 3-6mg bd Also for intractable hiccups Anti-nausea /Anti-vertigo Prochlorperazine 12.5mg/ml injection 12.5mg stat prn Anti-nausea Metochlopramide 10mg tabs 10mg tds Not in age <20 /Max 5 days Extrapyramidal effects Anti-nausea Metochlopramide 5mg/5ml liquid 10mg tds Not in age <20 /Max 5 days Extrapyramidal effects Anti-nausea Metochlopramide 10mg/2ml injection 10mg IVI/IMI tds Not in age <20 Anti-nausea Domperidone 10mg tabs Anti-nausea Domperidone Anti-nausea Ondansetron Anti-nausea Sedation effect Not in children <12 Extrapyramidal effects 10mg tds Max duration 1 week Cardiac disease /prolonged QT 5mg/5ml susp 5-10mg tds Max duration 1 week Cardiac disease /prolonged QT 4mg tab 4-16mg bd Prolonged QT Constipation Ondansetron 8mg tab 4-16mg bd Prolonged QT Constipation Anti-nausea Ondansetron 4mg (Zofran Melt®) 4-16mg bd Prolonged QT Constipation Anti-nausea Ondansetron 8mg (Zofran Melt®) 4-16mg bd Prolonged QT Constipation Anti-nausea Ondansetron 4mg/5ml syrup 2-8mg bd Prolonged QT Constipation Anti-nausea Ondansetron 2mg/ml injection 8-16mg IMI/IVI 12hrly Prolonged QT Max 16mg stat Anti-nausea Granisetron* 1mg tab 1mg bd Anti-nausea Granisetron* 2mg tab 2mg daily Anti-nausea Granisetron* 1mg/ml injection 1mg IVI (max 3mg daily) Analgesia Paracetamol 500mg tab 500-1000mg 6hrly Analgesia Paracetamol 500mg solutab 500-1000mg 6hrly Analgesia Paracetamol 60mg supp 60mg 6hrly Analgesia Paracetamol 125mg supp 125mg 6hrly Analgesia Paracetamol 250mg supp 250mg 6hrly Analgesia Paracetamol 500mg supp 500mg 6hrly Analgesia Paracetamol 120mg/5ml oral susp 60-240mg 6hrly Analgesia Paracetamol 250mg/5ml oral susp 125-500mg 6hrly NEUROLOGICAL Class Drug Formulation Dose Avail. Indications Contraindications Warning Analgesia Paracetamol 10mg/ml IV infusion 1g infused over 15min 6hrly Analgesia /Combination Paracetamol /Codeine 8/500mg tab (Co-codamol) 1-2 tabs 6hrly Analgesia /Combination Paracetamol /Codeine 30/500mg tab (Co-codamol) 1-2 tabs 6hrly Analgesia /Combination Paracetamol /Dihydrocodeine 8/500mg tab (Co-dydramol) 1-2 tabs 6hrly Analgesia /Combination Paracetamol /Dihydrocodeine 30/500mg tab (Co-dydramol) 1-2 tabs 6hrly Analgesia /Opiates Dihydrocodeine 30mg tab 30-60mg 4hrly prn Analgesia /Opiates Dihydrocodeine 10mg/5ml oral soln 10-30mg 4hrly prn Analgesia /Opiates Tramadol 50mg tab 50-100mg 4hrly (Max 400mg/24hrs) Analgesia /Opiates Morphine sulphate 10mg/5ml oral soln 5-40mg 4-6hrly Analgesia /Opiates Morphine sulphate 100mg/5ml oral soln 50-200mg 4-6hrly Analgesia /Opiates Morphine sulphate 10mg tab (Sevredol) 10-40mg 4-6hrly Analgesia /Opiates Morphine sulphate 20mg tab (Sevredol) 10-40mg 4-6hrly Analgesia /Opiates Morphine sulphate 10mg SR caps (Zomorph) 1 cap 12 hrly Analgesia /Opiates Morphine sulphate 30mg SR caps (Zomorph) 1 cap 12 hrly Analgesia /Opiates Morphine sulphate 60mg SR caps (Zomorph) 1 cap 12 hrly Analgesia /Opiates Morphine sulphate 100mg SR caps (Zomorph) 1 cap 12 hrly Analgesia /Opiates Morphine sulphate 200mg SR caps (Zomorph) 1 cap 12 hrly Analgesia /Opiates Morphine sulphate 10mg/ml injection 10-75mg SC/IMI 6hrly Analgesia /Opiates Morphine sulphate 15mg/ml injection 10-75mg SC/IMI 6hrly Analgesia /Opiates Morphine sulphate 20mg/ml injection 10-75mg SC/IMI 6hrly Analgesia /Opiates Morphine sulphate 30mg/ml injection 10-75mg SC/IMI 6hrly Analgesia /Opiates Oxycodone 5mg caps (OxyNorm) 5-60mg 12hrly Analgesia /Opiates Oxycodone 10mg caps (OxyNorm) 5-60mg 12hrly Analgesia /Opiates Oxycodone 20mg caps (OxyNorm) 5-60mg 12hrly Analgesia /Opiates Oxycodone 5mg MR tab (OxyContin) 5-120mg 12hrly Analgesia /Opiates Oxycodone 10mg MR tab (OxyContin) 5-120mg 12hrly Analgesia /Opiates Oxycodone 15mg MR tab (OxyContin) 5-120mg 12hrly Analgesia /Opiates Oxycodone 20mg MR tab (OxyContin) 5-120mg 12hrly Analgesia /Opiates Oxycodone 30mg MR tab (OxyContin) 5-120mg 12hrly Analgesia /Opiates Oxycodone 40mg MR tab (OxyContin) 5-120mg 12hrly Analgesia /Opiates Oxycodone 60mg MR tab (OxyContin) 5-120mg 12hrly Analgesia /Opiates Oxycodone 80mg MR tab (OxyContin) 5-120mg 12hrly Analgesia /Opiates Oxycodone 120mg MR tab (OxyContin) 5-120mg 12hrly Analgesia /Opiates Oxycodone 5mg/5ml liquid 5-100mg 12hrly Analgesia /Opiates Oxycodone 50mg/5ml liquid 5-100mg 12hrly Analgesia /Opiates Oxycodone 10mg/ml injection 10-100mg 12hrly Analgesia /NSAIDS Ibuprofen 200mg tab 400-600mg tds or qid Analgesia /NSAIDS Ibuprofen 400mg tab 400-600mg tds or qid Analgesia /NSAIDS Ibuprofen 600mg tab 400-600mg tds or qid Analgesia /NSAIDS Ibuprofen 100mg/5ml oral susp Max 30mg/kg/day in 3 or 4 doses Analgesia /NSAIDS Naproxen 250mg tab 250-500mg bd Analgesia /NSAIDS Naproxen 500mg tab 250-500mg bd Analgesia /NSAIDS Diclofenac 25mg tab 25-75mg bd Analgesia /NSAIDS Diclofenac 50mg tab 25-75mg bd Analgesia /NSAIDS Diclofenac 50mg disp tab 25-75mg bd Analgesia /NSAIDS Diclofenac 75mg MR caps 25-75mg bd Analgesia /NSAIDS Diclofenac 12.5mg supp 12.5mg PR bd Analgesia /NSAIDS Diclofenac 25mg supp 25mg PR bd Analgesia /NSAIDS Diclofenac 100mg supp 100mg PR daily Analgesia /NSAIDS Etoricoxib* 90mg tab 90-120mg daily Analgesia /NSAIDS Etoricoxib* 120mg tab 90-120mg daily Analgesia /Neuropathic pain Amitriptyline 10mg tab 10-75mg nocte Constipation / somnolence Analgesia /Neuropathic pain Amitriptyline 25mg tab 10-75mg nocte Constipation / somnolence Analgesia /Neuropathic pain Amitriptyline 50mg tab 10-75mg nocte Constipation / somnolence Analgesia /Neuropathic pain Gabapentin 100mg caps 300-600mg tds Titrate according to response Analgesia /Neuropathic pain Gabapentin 300mg caps 300-600mg tds Titrate according to response Analgesia /Neuropathic pain Gabapentin 400mg caps 300-600mg tds Titrate according to response Analgesia /Neuropathic pain Gabapentin 600mg caps 300-600mg tds Titrate according to response Analgesia /Neuropathic pain Pregabalin 25mg caps 75-300mg bd Titrate according to response Analgesia /Neuropathic pain Pregabalin 50mg caps 75-300mg bd Titrate according to response Analgesia /Neuropathic pain Pregabalin 75mg caps 75-300mg bd Titrate according to response Analgesia /Neuropathic pain Pregabalin 100mg caps 75-300mg bd Titrate according to response Analgesia /Neuropathic pain Pregabalin 150mg caps 75-300mg bd Titrate according to response Analgesia /Neuropathic pain Pregabalin 200mg caps 75-300mg bd Titrate according to response Analgesia /Neuropathic pain Pregabalin 300mg caps 75-300mg bd Analgesia /Neuropathic pain Lidocaine* 5% patches 1 patch topically daily Post-herpetic neuralgia Analgesia /Neuropathic pain Capsaicin 0.075% cream (Axsain cream) Apply spareingly qid Post-herpetic neuralgia + OA Anti-migraine drugs Sumatriptan 50mg tab 50-100mg asap after onset Second dose after 2 hours (Max 200mg) Anti-migraine drugs Sumatriptan 100mg tab 50-100mg asap after onset Second dose after 2 hours (Max 200mg) Anti-migraine drugs Sumatriptan 6mg/0.5ml injection 6mg s/c asap after onset Second dose after 1 hour (Max 12mg) Anti-migraine drugs Rizatriptan 10mg wafer (Maxalt) 10mg subling. asap after onset Second dose after 2 hours (Max 20mg) Anti-migraine drugs Zolmitriptan 5mg/0.1ml nasal spray (Zomig) 1 spray into nostril asap after onset Anti-migraine drugs Frovatriptan 2.5mg tab 2.5mg asap after onset For prolonged attacks Migraine prophylaxis Propranolol 80mg MR tab 80-160mg daily Also for essential tremor Migraine prophylaxis Propranolol 160mg MR tab 80-160mg daily Also for essential tremor Migraine prophylaxis Pizotifen 1.5mg tab 1.5mg nocte Dopaminergic drugs /Parkinsonism Levodopa /Benserazide 50/12.5mg caps (Madopar) 50-200mg tds (Levodopa component) Dopaminergic drugs /Parkinsonism Levodopa /Benserazide 50/12.5mg disp tab (Madopar) 50-200mg tds Dopaminergic drugs /Parkinsonism Levodopa /Benserazide 100/25mg caps (Madopar) 50-200mg tds Dopaminergic drugs /Parkinsonism Levodopa /Benserazide 100/25mg disp tab (Madopar) 50-200mg tds Dopaminergic drugs /Parkinsonism Levodopa /Benserazide 100/25mg MR caps (Madopar CR) 50-200mg tds Dopaminergic drugs /Parkinsonism Levodopa /Benserazide 200/50mg caps (Madopar) 50-200mg tds Dopaminergic drugs /Parkinsonism Carbidopa /Levodopa 12.5/50mg tab (Sinemet) 50-200mg tds (Levodopa component) Dopaminergic drugs /Parkinsonism Carbidopa /Levodopa 10/100mg tab (Sinemet) 50-200mg tds Dopaminergic drugs /Parkinsonism Carbidopa /Levodopa 25/100mg tab (Sinemet Plus) 50-200mg tds Dopaminergic drugs /Parkinsonism Carbidopa /Levodopa 25/250mg tab (Sinemet) 50-200mg tds Dopaminergic drugs /Parkinsonism Carbidopa /Levodopa 25/100 CR tab (Half Sinemet CR) 50-200mg tds Dopaminergic drugs /Parkinsonism Carbidopa /Levodopa 50/200 CR tab (Sinemet CR) 50-200mg tds Anti-muscarinic drugs /Parkinsonism Procyclidine 5mg tab 2.5-5mg tds Anti-muscarinic drugs /Parkinsonism Procyclidine 5mg/ml injection 2.5-5mg tds Substance dependence /Alcohol Chlordiazepoxide 5mg caps 10-20mg qid (5-7 days reducing reg) Substance dependence /Alcohol Chlordiazepoxide 10mg caps 10-20mg qid (5-7 days reducing reg) Substance dependence /Alcohol Thiamine 100mg tab 100mg tds Palliative care only Palliative care only Nausea / Addiction potential Nausea / Addiction potential Epilepsy Caution in Elderly + renal impairment Titrate according to response Use with rib #'s is unlicensed Second dose after 2 hours (Max 10mg) Second dose after 2 hours (Max 5mg) NEUROLOGICAL Class Drug Formulation Dose Avail. Indications Substance dependence /Alcohol Acamprosate 333mg tab 1-2 tabs tds Specifically for alcohol "cravings" Substance dependence /Alcohol Disulfiram 200mg tab 200mg daily (once stabilised) Specifically for alcohol "deterance" Substance dependence /Opiates Methadone* 1mg/ml oral soln See BCAT Guidelines Substance dependence /Opiates Buprenorphine /Naloxone* 2/0.5mg subling. tabs (Suboxone) See BCAT Guidelines Substance dependence /Opiates Buprenorphine /Naloxone* 8/2mg subling. tabs (Suboxone) See BCAT Guidelines Substance dependence /Opiates Buprenorphine /Naloxone* 16/4mg subling. tabs (Suboxone) See BCAT Guidelines Substance dependence /Smoking Varenicline 1mg tabs (Champix) 1mg bd (post stepped-up initiation) Substance dependence /Smoking Nicotine 7mg patches (Nicotinell) 1 patch daily Substance dependence /Smoking Nicotine 14mg patches (Nicotinell) 1 patch daily Substance dependence /Smoking Nicotine 21mg patches (Nicotinell) 1 patch daily Substance dependence /Smoking Nicotine 2mg gum (Nicotinell) 1 dose 1-2 hrly prn Substance dependence /Smoking Nicotine 4mg gum (Nicotinell) 1 dose 1-2 hrly prn Substance dependence /Smoking Nicotine 1.5mg lozenge (Niquitin mini's) 1 dose 1-2 hrly prn Substance dependence /Smoking Nicotine 2mg lozenge (Nicotinell) 1 dose 1-2 hrly prn Substance dependence /Smoking Nicotine 4mg lozenge (Niquitin mini's) 1 dose 1-2 hrly prn Contraindications Warning