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Intraoperative US of the Liver: Techniques and Clinical Applications Intern 盧佳文 2006-09-21 Outline Introduction Applications of Intraoperative US of the Liver Clinical Role of Intraoperative US Introduction Transducer Requirements Transducer Sterilization Technique for US of the Liver Relevant Intraoperative Anatomy Artifact Transducer Requirements 5-MHz side-fire T-shaped linear- or curvilineararray transducer – fit comfortably against the palm of the hand and between the fingers – have color Doppler flow and pulsed Doppler – provide good near-field resolution Transducer Sterilization Sterile condom sheaths – most commonly – The sheath must be long (typically about 1.5 m) – fit snugly around the transducer to avoid artifacts Low-temperature hydrogen peroxide gas plasma sterilization techniques – an entire sterilization cycle in 2–3 hours, – safe to use with heat-sensitive equipment, – enable the use of a sterile transducer without a condom sheath Glutaraldehyde or dialdehyde solution Ethylene oxide gas sterilization with high-temperature eratio Technique for US of the Liver Basic setting Technique – in a transverse position, starting at the most lateral margin of the left lateral segment II and extending toward the right side Technique – bathing the field with sterile saline for very near lesion Relevant Intraoperative Anatomy Hepatic vein – the transducer is held in a transverse midline position and angled toward the beating heart Portal vein – Placing the transducer on the undersurface of the liver, over segment IV, and angling the transducer toward the porta hepatis Relevant Intraoperative Anatomy Specific arteries – a replaced right hepatic artery that arises from the superior mesenteric artery and courses posterior to the portal vein – replaced or accessory left hepatic artery that arises from the left gastric artery and courses through the ligamentum venosum Artifact The cut margin of a liver segment is often echogenic because of small amounts of gas that enter the parenchyma and sinusoids – after cautery or sonication – Should D/D with mucinous colorectal cancer metastases Acoustic shadowing produced by palpation of the posterior liver surface Applications of Intraoperative US of the Liver Survey for Primary or Metastatic Lesions Lesion Characterization Guidance for Tumor Resection and Metastasectomy Evaluation of Vessel Patency Liver Transplantation Tumor Ablation Biliary Disease Extrahepatic Disease Survey for Primary or Metastatic Lesions Resolution: – larger than 2 mm Sensitivity: – more than 90% of 25%–35% more lesions than does preoperative imaging Lesion Characterization Hemangioma – – – – Varied appearance Palpation Doppler Vessel involvement Lesion Characterization Metastasis – Bull’s-eye or target sign Colon cancer Carcinoid tumors FNH sarcoma Lesion Characterization Benign and malignant tumors frequently coexist Guidance for Tumor Resection and Metastasectomy the presence or absence of vascular occlusion or invasion margins of 1–2 cm are required for adequate lesion resection Guidance for Tumor Resection and Metastasectomy Evaluation of Vessel Patency Benign – displacement and effacement of vessels Malignant – invasion and occlusion of vessels Evaluation of Vessel Patency a tumor-associated thrombus: – avascular a tumor thrombus : – an arterial waveform at pulsed Doppler evaluation Clinical Role of Intraoperative US Schmidt et al showed a sensitivity and specificity of 98% of 95%, respectively, for detection of colorectal cancer metastases intraoperative US still provided additional useful information in 50% of their patients, and this information resulted in a change in the surgical procedure in 15% 40% of the lesions demonstrated by intraoperative US were neither visible nor palpable at surgery