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Malignant Salivary Gland Neoplasms Proforma Mandatory questions (i.e. protocol standards) are in bold (e.g. S1.03). Sex Family name Male Female Given name(s) Intersex/indeterminate Ethnicity Unknown Date of birth Aboriginal/Torres Strait Islander DD – MM – YYYY Other ethnicity: Patient identifiers e.g. MRN, IHI or NHI (please indicate which) S1.03 Accession number DD – MM – YYYY Requesting doctor - name and contact details S1.02 Clinical details Other anatomical site Type of operation incisional biopsy excisional biopsy of minor gland Laterality of the lesion resection of submandibular gland Left Right extended resection submandibular gland (record extent of anantomicalresection) Clinical history resection of sublingual gland +facial nerve sacrifice - facial nerve sacrifice superficial parotidectomy total parotidectomy Clinical TNM stage facial nerve preservation facial nerve sacrifice extended radical total parotidectomy (includes resection of parotid gland, facial nerve, other neck dissection Clinical diagnosis or differential diagnosis masseter muscle, zygoma and mandible) selective modified radical radical extended radical Laterality of neck dissection Left Right Date of request Bilateral New primary cancer or recurrence New primary Recurrence - regional Recurrence - distant Details: Nodal levels included (tick all that apply) (Record separately for each laterality) submental (IA) upper jugular (IIA) middle jugular (III) posterior triangle (VA) submandibular (IB) Pre-operative or prior radiotherapy administered upper jugular (IIB) Yes None adminstered lower jugular (IV) Details: posterior triangle (VB) other nodal tissue (specify) Anatomical site of neoplasm Parotid gland Submandibular gland Sublingual gland whole Minor salivary gland superficial lobe deep lobe Site(s) Involvement of adjacent structures S1.04 Principal clinician Version 0.1 Proforma: Salivary Gland Neoplasms Structured Reporting Protocol 1st Edition Page 1 of 5 G1.01 Other relevant details S2.06 Macro. evidence of extraparenchymal extension Absent Present Neck dissection S2.07 Macroscopic findings S2.01 Specimen labelled as Absent Present Specify type: selective modified radical radical extended radical S2.02 Specimen type (choose all that apply) Laterality of neck dissection: Parotid gland - whole Left Parotid gland - superficial lobe length mm Submandibular gland Sublingual gland Minor salivary gland Bilateral Dimensions: Parotid gland - deep lobe Right Description x width mm x thickness mm (Note: Include for example any anatomical structures): Specify sites Neck dissection Biopsy incisional S2.08 Biopsy excisional MACROSCOPIC LYMPH NODE STATUS Not received Biopsy resection Other (specify) Received submental (level IA) Largest node: G2.01 S2.03 S2.04 Specimen integrity submandibular (level IB) Intact Fragmented Largest node: upper jugular (level IIA) Specimen received Fresh Formalin Largest node: upper jugular (level IIB) Specimen measurements length mm x width mm x thickness Largest node: mm middle jugular (level III) S2.05 Description & measurements of lesion Size length mm Site x width mm x thickness mm Largest node: lower jugular (level IV) Largest node: (Note: Site should include laterality) posterior triangle (level VA) Appearance Largest node: posterior triangle (level VB) Largest node: Version 0.1 Proforma: Salivary Gland Neoplasms Structured Reporting Protocol 1st Edition (Note: if bilateral record for both): number received mm number received mm number received mm number received mm number received mm number received mm number received mm number received mm Page 2 of 5 G2.02 Other macroscopic comments Site(s) (Choose all that apply) Skin Mandible Ear canal Facial nerve Base of skull S2.09 Pterygoid plates Block identification key Carotid artery encasement Other (specify) S3.05 Microscopic findings S3.01 Perineural involvement Histological tumour type Acinar cell carcinom Mucoepidermoid carcinoma Adenoid cystic carcinoma S3.06 Not identified Present Lymphovascular invasion Polymorphous low grade adenocarcinoma Epithelial-myoepithelial carcinoma Not identified Present Clear cell adenocarcinoma, NOS Basal cell adenocarcinoma Sebaceous carcinoma S3.07 Sebaceous lymphadenocarcinoma SURGICAL MARGIN STATUS Margin 1 (specify) Cystadenocarcinoma Low-grade cribiform cystadenocarcinoma Mucinous adenocarcinoma Involved Not involved Oncocytic carcinoma Distance to tumour Salivary duct carcinoma Adenocarcinoma, NOS Margin 2 Myoepithelial carcinoma (specify) Carcinoma ex pleomorphic adenoma Carcinosarcoma, NOS Metastasizing pleomorphic adenoma Involved Not involved Squamous cell carcinoma Distance to tumour Small cell carcinoma Large cell carcinoma Lymphoepithelial carcinoma (specify) HISTOLOGICAL GRADE Grading system: Involved Not involved Distance to tumour Grade/score: S3.08 S3.04 x width mm x thickness mm Involvement of adjacent structures (Note: if bilateral record for both): Total number of nodes Tumour size length mm mm Cervical lymph node status submental (level IA) S3.03 mm Margin 3 Sialoblastoma S3.02 mm Not applicable Absent Present Number of involved nodes submandibular (level IB) Total number of nodes Number of involved nodes List sites Version 0.1 Proforma: Salivary Gland Neoplasms Structured Reporting Protocol 1st Edition Page 3 of 5 S3.08 Lymph node status (cont.) Distance from closest perinodal surgical margins upper jugular (level IIA) mm Total number of nodes Number of involved nodes Permeation of perinodal lymphatics Absent upper jugular (level IIB) Total number of nodes Present G3.01 Number of involved nodes Other microscopic comments middle jugular (level III) Total number of nodes Number of involved nodes Ancillary test findings lower jugular (level IV) S4.01 Total number of nodes Number of involved nodes IMMUNOHISTOCHEMICAL STAINS No Pending Yes Complete details: posterior triangle (level VA) Positive Abs Total number of nodes Negative Abs Number of involved nodes Equivocal Abs posterior triangle (level VB) Interpretation Total number of nodes Number of involved nodes Largest metastastic deposit Clinical significance Location Dimensions length mm S4.02 x width mm x thickness mm Extracapsular spread Absent Present Pending Yes Complete details: Performing laboratory Extent of invasion from nodal capsule: IN-SITU HYBRIDISATION No Result mm Number of nodes with extracapsular spread: If 1, record the no. of foci /tongues Conclusion Structures involved in extracapsular spread: Person responsible for reporting Version 0.1 Proforma: Salivary Gland Neoplasms Structured Reporting Protocol 1st Edition Page 4 of 5 S4.03 S5.01 Stage & stage group## CYTOGENETICS No Pending Yes Primary Tumour (T) Complete details: Performing laboratory Result TX Primary tumour cannot be assessed T0 No evidence of primary tumour T1 Tumour 2 cm or less in greatest dimension without extraparenchymal extension* T2 Tumour more than 2 cm but not more than 4 cm in greatest dimension without extraparenchymal extension* T3 Tumour more than 4 cm and/or tumour having extraparenchymal extension* T4a Moderately advanced disease. Tumour invades skin, mandible, ear canal, and/or facial nerve T4b Very advanced disease. Tumour invades skull base and/or pterygoid plates and/or encases carotid artery Notes: Extraparenchymal extension is clinical or macroscopic evidence of invasion of soft tissues. Microscopic evidence alone does not constitute extraparenchymal extension for classification purposes. Conclusion Regional Lymph Nodes (N) Person responsible for reporting Synthesis and overview S5.01 AJCC Tumour stage (see opposite) T N M NX Regional lymph nodes cannot be assessed N0 No regional lymph node metastasis N1 Metastasis in a single ipsilateral lymph node, 3 cm or less in greatest dimension N2 Metastasis in a single ipsilateral lymph node, more than 3 cm but not more than 6 cm in greatest dimension, or in multiple ipsilateral lymph nodes, none more than 6 cm in greatest dimension, or in bilateral or contralateral lymph nodes, none more than 6 cm in greatest dimension N2a Metastasis in a single ipsilateral lymph node, more than 3 cm but not more than 6 cm in greatest dimension N2b Metastasis in multiple ipsilateral lymph nodes, none more than 6 cm in greatest dimension N2c Metastasis in bilateral or contralateral lymph nodes, none more than 6 cm in greatest dimension N3 Metastasis in a lymph node, more than 6 cm in greatest dimension Distant Metastasis (M) S5.02 G5.01 G5.02 Stage Grouping Year of publication and edition of cancer staging system No distant metastasis M1 Distant metastasis Anatomic Stage/Prognostic Groups Diagnostic summary Include: Type of operation; Anatomical site/ laterality; Tumour type; Histological grade; Tumour dimensions; Extraglandular extension of tumour; LVI; Perineural invasion; Involved or close margins with measurements; Type of neck dissection (if present); Presence or absence of metastatic tumour in lymph nodes and level of involved nodes; Presence or absence of extracapsular spread of tumour; Ki-67 index; Tumour stage. M0 Stage I T1 N0 M0 Stage IVA T1 N2 M0 Stage II T2 N0 M0 T2 N2 M0 Stage III T3 N0 M0 T3 N2 M0 T1 N1 M0 T4a N2 M0 T2 N1 M0 Stage IVB Any T N3 M0 T3 N1 M0 Stage IVA T4a N0 M0 N1 M0 ## T4a Stage IVC T4b Any N M0 Any T Any N M1 Used with the permission of the American Joint Committee on Cancer (AJCC), Chicago, Illinois. The original source for this material is the AJCC Cancer Staging Manual, Seventh Edition (2010) published by Springer Science and Business Media LLC, www.springerlink.com . Other relevant comments Worksheet prepared by: On: DD – MM – YYYY Version 0.1 Proforma: Salivary Gland Neoplasms Structured Reporting Protocol 1st Edition Page 5 of 5