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Mikbaz I - moed A - 4.01.2007 Part 1 - Introduction 1. All of the following are correct regarding PET FDG imaging in patients with cancer, except: a. This imaging is based on simultaneous detection of 2 gamma rays, emitted at 180 degrees from each other, after annihilation of a positron emitted from a radioactive isotope with an electron. b. One of the advantages of the test is the option to use FDG not only for imaging, but also for treatment of metastases. c. One of the advantages of the test is the possibility to scan the whole body following a one-time injection of the radioactive material. d. The PET FDG test can detect active malignant tissue even when the CT shows no pathological findings. 2. The following statements regarding the localization mechanisms of the substances used in nuclear medicine are true, except: a. Bone scan is based upon chemical absorption of the substance on the hydroxyapatite crystals of the bone. b. Lung scan is based upon simple diffusion of the substance to the lungs. c. Thyroid scan is based upon active absorption against concentrations gradient. d. PET FDG scan is based upon intracellular metabolism. 3. All of the following are correct regarding renal scan, except: a. Using the scan it is possible to diagnose rejection of an implanted kidney both from a relative and from dead. b. In order to apprehend occlusion of renal venous drainage, a drug, such as capoten, can be used. c. Renal scan is a dynamic scan. d. Renal inflammations can be diagnosed using DMSA renal scan. 4. All of the following are correct regarding nuclear medicine, except: a. Imaging in nuclear medicine is based upon injection of a radioactive substance and appreciation of physiological processes in the body. b. In order for a radioactive atom to be appropriate for use in nuclear medical imaging, it has to have a very long half life (at least several days). c. The advantage of combined imaging (PET/CT, SPECT/CT) is in the ability to locate anatomically the findings of the scan. d. SPECT test presents the findings in three dimensions and is efficient in localizing the findings in regions of compound anatomy. -1- 5. Which of the following is true regarding bone scan for diagnosing stress fractures : a. Bone scan can demonstrate stress fractures even when the X-ray imaging of the area is normal. b. Bone scan is not efficient in diagnosing stress fractures in women. c. Tagged WBC scan is sometimes used as a complimentary to bone scan in diagnosing stress fractures. d. The specificity of bone scan for diagnosing stress fractures is high, but the sensitivity is relatively low. 6. All of the following are correct regarding lung scan, except: a. The injected particles "get stuck" in the pulmonary pre-capillaries in the ratio of 1:1000. b. Lung scan is efficient in demonstrating pulmonary emboli and lung malignancies. c. The injected substance used in the scan is albumin macro-aggregates. d. During the test, a radioactive substance is injected into the blood stream, and a radioactive gas is given by inhalation. 7. The diagnostic process of hyperparathyroidism can be initiated by an incidental finding of high values of: a. TSH and adrenal hormones b. Calcium c. EDTA d. Fluorid e. The clinical lab has no role in diagnosing diseases 8. A blood tube that has been standing for long time before being transmitted to the laboratory, would have an erroneous reading of: a. Sodium and potassium b. Calcium and phosphorus c. Potassium and calcium d. Glucose and sodium e. Potassium and glucose 9. A patient is admitted to the ER with high fever and fulminant inflammatory process, and is transmitted to the ICU. In the ICU various blood tests have been taken, and, among other findings, a very high serum potassium level is found. How should this finding be regarded? a. The finding is of great importance in the treatment course of the patient b. The finding should be regarded suspiciously, as in the current state of the patient is can be false positive c. A fulminant inflammatory process augments all the electrolytes, thus the finding is reasonable d. The finding should be regarded along with the serum sodium value in order to define the appropriate treatment -2- 10. A high specificity level is required for a test intended to diagnose: a. A disease with high incidence in the population b. A severe disease that has an efficient treatment c. A severe disease with no efficient treatment d. A disease with characteristics that are difficult to diagnose at physical examination 11. What is the meaning of poor R-wave progression at leads V1-4: a. Is common in weight lifters b. Is a sign of significant pulmonary disease c. Indicates a previous antero-septal MI a. Indicates a technical problem in the connections of the ECG electrodes 12. What is the electrical axis in the strip at picture number 1: a. Minus 45 degrees b. 0 degrees c. 30 degrees d. 90 degrees 13. What is the most correct statement regarding picture number 2: a. Rhythm can not be determined, axis +75 b. Sinus rhythm, axis +110 c. Sinus rhythm, PR interval longer than normal, axis +90 d. Sinus rhythm, normal PR interval, axis +75 14. What is the most correct statement regarding picture number 3: a. NSR (normal sinus rhythm), normal PR interval, normal axis b. Sinus bradycardia, normal PR interval, normal axis c. Sinus bradycardia, normal PR interval, left axis d. Sinus bradycardia, normal PR interval, right axis 15. From whom was attained the ECG strip at picture number 4: a. Sixth year medical student during final exams, suffering from anxiety attack and increased adrenaline release b. 75 year old man, suffering from hypertension for many years c. 23 year old woman, suffering from primary pulmonary hypertension d. 50 year old doctor, without a history of heart disease 16. From whom was attained the ECG strip at picture number 5: a. Sixth year medical student during final exams, suffering from anxiety attack and increased adrenaline release b. 75 year old man, suffering from hypertension for many years c. 23 year old woman, suffering from primary pulmonary hypertension d. 50 year old doctor, without a history of heart disease -3- 17. Upper motor neuron syndrome features: a. Increased superficial reflexes b. Decrease in tendon reflexes c. Plantar flexor response d. Spastic tonus e. Flaccid tonus Pictures: Picture 1 Picture 2 Picture 3 -4- Picture 4 Picture 5 Possible answers: 1. b 2. 3. b 4. b 5. a 6. 7. 8. 9. c 10. c 11. d 12. d 13. c 14. d 15. c 16. d -5-