Download 四川大学期末考试试题

四 川 大 学 期 末 考 试 试 题（闭卷 B）
（2011—2012 学年 第Ⅱ学期）
课程号：501106030 课序号：0,1 课程名称：医学微生物 I 任课教师：
成绩：
适用专业年级：10 级医学八年制、基础医学 学生数：130 印题份数：150 学号：
姓名：
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题号
一
二
三
四
五
总分
分数
Ⅰ. Define following terms (21%)
1. Peptidoglycan
2. tuberculin skin test
3. Disinfection
4. Transduction
5. Chlamydia
6. Dane particle
7. antigenic drift
II．Fill the blanks (30%)
1． The basic morphology of bacterial include ____ _______, the ____
_____; and the
___________________
2． The
special
structures
of
bacteria
include
_____________,
__________.,
_____________, and _____________.
3． According to the cellular structure, microorganism could be classified into three types,
such as____________, _________________and _____________.
4.
During
bacterial
metabolism,
some
products
are
harmful
to
people,
such
as___________________, and ______________.
5. The procedures of Gram’s stain including __________, _________, _________, and
_________steps. The Gram’s positive bacteria appeared _________colour.
1
6. The
unit
of
measurement
is
for
virus
is_
______________;
bacteria
.
7. The virus replication cycle includes
,
8.
for
HIV
, and
contains
including
,
three
structural
,
five steps.
genes
, and
9. According to the virulence of bacteriophage,
and
,
required
for
a
replication,
genes.
usually phages could be classified into
phages.
10. mycoplasma is believed to be devoid of
.
Ⅲ. True (+) or False (- ) (9%)
1. The cell wall of Mycobacteria contains a lot of lipid.
(
)
2. Flagellum is bacterial only locomotive organ.
(
)
3. Plasmids capable of mediating transformation carry genes coding sex pilus on the surface
of the donor.
(
)
4. Sabouraud’s medium usually was used to culture medical fungi.
(
)
5. The RNA genomes of influenza virus possess eight separate segments.
(
)
6. The serotype of V.cholerae arrange often according to O：K：H.
(
)
7. α-hemolytic streptococcus has strong pathogenicity and can induce various diseases. (
)
8. The chemical nature of Prion is infectious protein.
)
(
9. The Viruses virulence is measured by LD50 or TCID50.
(
)
Ⅳ. Choose the correct answer, only one answer is correct (10%)
1. The main cause of multiple drug resistance produced by bacteria is (
A. genetic mutation
B. genetic transfer and recombination
D. base transversion
E. chromosomal rearrangement
)
C. obtain of R plasmid
2. Which position is convenient to influenza virus multiplication in embryonated eggs?
A. Yolk sac
B. Allantoic cavity
C.
D. air sac
amniotic cavity
E. chorioallantoic cavity.
3. The eclipse period of viral infection usually occur in（
A. adsorption
B. penetration
）phase of viral replication cycle.
C. biosynthesis
2
D. assembly and maturation
E. release
4. Which material of following contributes to Clostridium tetani pathogenicity?
A. Endotoxin
B. Capsule
C. Enterotoxin
D. Spore
E. Tetanospasmin
5. The type of pathogenic E.coli which show watery diarrhea is (
A. ETEC
B. EPEC
C. EIEC
)
D. EHEC
6. Which microorganism is studied in BSL-3 or BSL-4 laboratory (
A. HBV B. S. dysenteriae
C. HIV
D. HAV
E. EAEC
)
E. Neisseria meningitidis
7. The disease which can prevent by inoculation of corresponding toxoid is (
A. Tuberculosis
B. Typhoid fever
D. Tetanus
E. Dysentery
C. Pneumonia
8. Hfr bacteria can increase transferred frequency of (
) gene.
A. Virulent phage
B. Temperate phage
D. Plasmid
E. Transposable element
9. The corroborative or confirmed test of AIDS is (
)
C. Chromosome
).
A. Detection DNA through PCR
B. Separation and culture HIV
C. Detection antibody through Western blot
D. Detection P24 antigen of HIV
E. Detection RNA through RT－PCR
10. The reproductive organs of fungi is (
)
A. Vegetative mycelium
B. Aerial mycelium
D. Fungal spore
E. Pseudohypha
C. Reproductive mycelium
V. Answer questions (30%)
1. What are the differences between exotoxin and endotoxin?
(10%)
2. Please state the mechanisms of interferon (IFN) against virus. (10%)
3. What are the mechanisms of CD4+ T lymphocytes destroyed by HIV after its infection?
(10%)
注：1 试题字迹务必清晰，书写工整。
2 .题间不留空，一般应题卷分开
3. 务必用 A4 纸打印
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