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Are you exposed to Isoflurane through your research?
EXPOSURE LIMITS: NIOSH recommends an exposure level of 2 parts
per million (ppm) that should not be exceeded over a one hour period
for anesthetic gases.
POPULATIONS AT RISK: While research in this area is lacking, exposure to
anesthetic gases have been associated with adverse reproductive outcomes
including: impaired fertility, miscarriage, low birth weight, preterm birth, and
birth defects. There is enough evidence to suggest that avoiding exposure to
anesthetic gases while planning to get pregnant or when pregnant is
recommended. Long term exposure has also been associated with adverse
reproductive outcomes in spouses of men exposed to anesthetic gases.
CONTROL MEASURES:
 Notify others around you when working with isoflurane.
 Make sure the charcoal canister is not full or expired, the canister must be
weighed before and after every use, and the weights recorded in the log.
 Whenever possible the anesthesia machine should be used in an externally
ventilated hood.
 Turn off delivery when gas is not needed and use the lowest functional flow
rate necessary.
 Refer to the Isoflurane Reference Guide by your machine for more tips to
reduce exposure
CONTACT INFORMATION:
- If you are pregnant or you or your partner are
planning a pregnancy, contact UHS Occupational
Medicine for a risk assessment for isoflurane
exposure 265-5610.
- To get isoflurane monitoring done and establish
potential exposure levels during your procedure,
contact UHS Environmental and Occupational Health
at 890-1992.
- To get fit-tested for a respirator effective for
isoflurane contact UHS Occupational Medicine at
265-5610.