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Superoxide dismutase-3 promotes full expression of the EPO response to hypoxia by Hagir B. Suliman, Mervat Ali, and Claude A. Piantadosi Blood Volume 104(1):43-50 July 1, 2004 ©2004 by American Society of Hematology SOD3 and EPO mRNA distribution in kidneys of adult mice. Hagir B. Suliman et al. Blood 2004;104:43-50 ©2004 by American Society of Hematology Distribution of renal SOD3 protein in adult mice. Hagir B. Suliman et al. Blood 2004;104:43-50 ©2004 by American Society of Hematology Immunofluorescence for SOD3 and EPO protein in kidneys of animals exposed to hypoxia for 6 hours. Hagir B. Suliman et al. Blood 2004;104:43-50 ©2004 by American Society of Hematology Hematocrit response to hypoxia in Wt and KO mice. Hagir B. Suliman et al. Blood 2004;104:43-50 ©2004 by American Society of Hematology Renal EPO mRNA transcription and HIF-1 expression after hypoxia. Hagir B. Suliman et al. Blood 2004;104:43-50 ©2004 by American Society of Hematology Renal NOX4 mRNA expression after hypoxia. Hagir B. Suliman et al. Blood 2004;104:43-50 ©2004 by American Society of Hematology Effect of hypoxia on renal eNOS expression and plasma NOx. (A) Representative Western blots showing eNOS antibody detected a single band at the expected 140 kDa; hypoxia increased eNOS staining intensity in both strains of mice. β-actin was used for normali... Hagir B. Suliman et al. Blood 2004;104:43-50 ©2004 by American Society of Hematology Oxidative and nitrosative stress in kidneys of mice exposed to acute hypoxia. Hagir B. Suliman et al. Blood 2004;104:43-50 ©2004 by American Society of Hematology