Download RISK OF COMPLICATIONS IN RELATION TO BLOOD DONATION

Donor reaction and complication in blood donation
RISK OF COMPLICATIONS IN RELATION
TO BLOOD DONATION
B. Aagaard, B. Samuelsen, J. Jorgensen, K. Titlestad, and S.P. Johnsen*.
Blood Transfusion Centre, Dept. of Clinical Immunology and Dept. of Clinical Epidemiology*
Aarhus University Hospital, Denmark.
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Donor reaction and complication in blood donation
DATA
A standardized form was filled in, when blood donors
developed symptoms at the time of or after blood
donation.
The form was sent to the central organization of
Blood Donors in Denmark (BiD). These reports are
the basis for the analysis.
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Donor reaction and complication in blood donation
COMPLICATIONS
—
divided into two groups
1)
Needle injuries included:
haematoma
pain
paresthesia
2)
Vasovagal reactions included:
discomfort
syncope
seizure
Few complications (poorly described or unclassified) were excluded –
9 per 578 (1997-2002)
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Donor reaction and complication in blood donation
OCCURRENCE
No. of complications per 100,000 donations
45
40
vasovagale
35
needle injuries
30
total
25
20
15
10
5
0
1997
1998
1999
2000
2001
2002
year
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Donor reaction and complication in blood donation
OCCURRENCE of complications
Conclusion:
The number of needle injuries has increased from
13 to 29/100,000 donations, resulting in a
corresponding raise in the total number of reported
complications
most likely, the increase is a result of enhanced
attention among staff as well as donors.
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Donor reaction and complication in blood donation
Severe complications (SC)
Symptoms lasting ≥ 12 months
1997–2001
Total no. of
complications
N = 436
No. of SC,
% of total
complications
Vasovagal reactions
107
1 (0,2%)
Needle injuries
329
48 (11%)
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Donor reaction and complication in blood donation
SC ─ in relation to age
RC = reported complications
140
num ber
120
SC
RC
100
80
60
40
20
0
18-30
31-40
41-50
50-65 age/year
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Donor reaction and complication in blood donation
SC and disablement
Conclusion:
The number of SC increased steadily with age from
5 – 19% of total reported complications
same group of age.
The risk of disablement, for donors with a
complication, increased with age.
Needle injury is the event most likely to cause
severe complications and disablement.
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Donor reaction and complication in blood donation
Summary
Occurrence:
disablement
SC
10
needle injuries
51
donations
3 per year
367,000
as a mean from 1997 ─ 2001
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Donor reaction and complication in blood donation
Conclusion of analysis
The risk of complication related to bleeding of donor
was low. Nevertheless, for donors suffering
prolonged and life lasting symptoms still
unacceptable.
Roughly, SC in blood donation correlates to the risk
of serious complications for the patient in blood
transfusion!
(Taaning, E. and Jorgensen, J., p 24.14, ISBT 2004)
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Donor reaction and complication in blood donation
Conclusion of analysis
SC were most often developed after needle injuries.
Efforts have been made to reduce their occurrence:
Change in needle insertion technique
Intensive treatment of needle injuries
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Donor reaction and complication in blood donation
Conclusion of analysis
Severe complications
related to donation
related to transfusion
3/100,000 donations
4/100,000 components
The risk of severe complications is the same for
blood donors and transfused patients!
(Taaning, E. and Jorgensen, J., p 24.14, ISBT 2004)
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