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Transcript
Bovilis® IBR Marker Live
The ONLY single dose IBR Marker vaccine
for use either Intramuscularly1 or Intranasally1
Herd level prevalence IBR by County
Infectious Bovine Rhinotracheitis The hidden threat
Respiratory disease is a major cause of financial loss to cattle
farmers. While respiratory disease is almost exclusively a disease
of younger cattle, IBR is commonly associated with older calves
2
and adult stock. With 75% of herds testing positive for IBR , this
is an issue that farmers can no longer afford to ignore or leave to
chance.
60-64%
75%
of herds
test positive
for IBR
2
65-69%
70-74%
75-79%
80-84%
85-89%
90-94%
95-100%
2
A recent seroprevalence study in Ireland showed that almost
75% of herds had evidence of exposure to IBR. The
seroprevalence for dairy and beef herds was not significantly
different but there was a significant provincial difference, with
Leinster having the highest incidence and Munster the lowest.
County-level seroprevalence information from the same study,
not included in the publication, are given in the map above.
Diagnosis
1
Infectious Bovine Rhinotracheitis
(IBR) can be easily diagnosed using
bulk milk samples, or blood
samples, nasal swabs, tissue
samples from individual animals.
2
Advance of infection
Poor housing, insufficient ventilation,
over-crowding and stress can all contribute
to the spread of IBR, but as the signs of the
disease are not exclusive to IBR the virus
can often be missed, allowing it to circulate
throughout the main herd.
To succeed in the battle against IBR, correctly
recognising the signs of the disease is vital.
Raised temperature
Milk drop
Nasal discharge
Coughing
Conjunctivitis
Reduction of food intake
Abortion
3
Break the cycle of IBR
Bovilis IBR Marker Live offers you the choice of I/M
or I/N routes1 enabling you to break the cycle with just
one single shot.
Bovilis IBR Marker Inac offers you an inactivated version
of the vaccine for use in animals over 3 months old,
which can be used to boost Bovilis IBR Marker Live.
All the ammunition you need
To help you plan for
the future you’ll want
to be armed with the
best tools for the job.
So arm yourself with
Bovilis IBR Marker live
The Only Single
Dose IBR Marker
vaccine for use
either IM or IN1
Bovilis IBR Marker Live
A choice of either I/M or I/N routes1
Single dose primary course
Vaccination possible from 2 weeks of age
Easy whole herd vaccination including pregnant
animals
Significantly reduces clinical signs and viral
excretion
Can be used concurrently with Bovilis
Bovipast RSP
4
Bovilis IBR Marker Vaccines Live and Inac
3 Possible Vaccination Regimes for cattle over 3 months old
Primary Vaccination
1
Bovilis IBR Marker Live
(one shot)
Future proof farms against IBR
Booster
6 months
Bovilis IBR Marker Live
In order to try and eradicate IBR, it is necessary to be able to tell an infected animal
from a non-infected one - which is impossible with standard (non-marker) IBR
vaccines. Because of this, marker vaccines have been developed.
OR
2
Bovilis IBR Marker Live
(one shot)
6 month
Bovilis IBR Marker Inac
OR
Bovilis IBR Marker Inac
3
4 weeks
Many European countries already have, or are trying to eradicate IBR to prevent the
losses it causes and to reduce barriers to trade in live cattle. A growing movement
across the EU to eradicate IBR could be a barrier to trade for those countries without
control or eradication schemes in place.
6 months
Marker vaccines give you all the benefits of a traditional IBR vaccine. They also give
you the freedom to identify and export healthy animals to IBR-eradicating parts of
Europe. This gives you the added peace of mind that you will also be prepared for the
future, should an eradication programme come into force in Ireland or the UK.
Bovilis IBR Marker Inac
Differential test for marker vaccinated and IBR cow
Bovilis IBR Marker Inac
1. IBR infected cow
2. Traditional vaccine
3. Bovilis IBR marker
BHV-1
Product
Characteristics
Bovilis IBR
Marker Inac
Intranasal
Intramuscular
Administration route
Yes
Yes
2 shots
Onset of immunity
4
days
14
days
21 days after
primary course
6
months
6
months
6
months
Duration of immunity*
(re-vaccination interval)
5
Bovilis IBR
Marker Live
Intramuscular
Yes
Test: Y=anti gB
Y=anti gE
Test: Y=anti gB
Y=anti gE
Y= Antibodies
Test: Y=anti gB
gB and gE = Proteins on surface of virus
6
Bovilis® IBR Marker Live The Only Single Dose IBR Marker
vaccine for use either IM or IN1
Available
in 5 dose,
10 dose (R.O.I. only)
25 dose and 50 dose
packs
For further details contact your vet or call MSD
Animal Health on (00353)-(0)1-2970220
Bovilis IBR Marker Inac contains inactivated antigen of BHV-1 strain GK/D, 60 Elisa units per dose of 2 ml. For the active
immunisation of cattle to reduce the intensity and duration of clinical signs (pyrexia) induced by an infection with BHV-1 as
well as to reduce the replication and nasal excretion of the field virus. Legal Category Nth. Irl. POM-V ; R.O.I. POM(E) .
Bovilis IBR Marker live contains live, attenuated IBR marker vaccine BHV-1 (strain GK/D). For the active immunisation against
infectious bovine rhinotracheitis virus. Bovilis IBR Marker live may only be prescribed by your veterinary surgeon, from whom
advice should be sought. Withdrawal period: zero days. Legal Category POM-V in Nth. Irl. and POM(E) in R.O.I.
Bovipast RSP contains inactivated bovine Respiratory Syncytial Virus (Strain EV908), Parainfluenza 3 virus (strain SF-4 Reisinger)
and inactivated Mannheimia (Pasteurella) haemolytica (serotype A1). Legal category POM-V in Nth. Irl. and POM(E) in R.O.I.
®Bovilis is a registered trademark of Intervet International.
Use Medicines Responsibly.
1. From the age of 3 months onwards. Between 2 weeks and 3 months old - intranasal only and
boost at 3-4 months old
2. Cowley DJB et al, Aspects of bovine herpesvirus infection in dairy and beef herds in the Republic of Ireland. Acta Veterinaria
Scandinavica 2011, 53:40.
R11-024
*For cattle over 12 weeks of age.
MSD Animal Health,
Red Oak North, South County Business Park, Leopardstown, Dublin 18, Ireland.
Tel. (00353)-(0)1-2970220 Website: www.msd-animal-health.ie
www.ibr-marker.com