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2 hour lecture Wednesday 1 hour lecture Thursday Adaptation and cell injury: hypoxic, Calcium deposition, cell death and free radical and chemical tissue necrosis, apoptosis Inflammation; vascular stage an cellular stage, and Cytokines. exudates, chronic inflammation wound healing and factors affecting wound healing Hypersensitivity reactions: type I,II,III,IV and diseases HIV and AIDS Fluid an electrolyte imbalance Atherosclerosis and coronary heart disease Hypertension and heart failure Respiratory disorders: ARDS and obstructive lung disease Tuberculosis , pneumonias and vascular lung diseases, lung cancer Digestive disorders: intestinal obstruction, peptic ulcer disease Inflammatory bowel disease, portal Renal disorders: renal obstruction, hypertension, jaundice, viral renal stones, hepatitis and cirrhosis. UTI, glomerular disease, acute renal failure Chronic renal failure CNS disorders: brain trauma, increased intracranial hypertension, spinal shock ,stroke Epilepsy and degenerative diseases