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Table S3. Transcription regulatory element abbreviations LHXF ABDB Abdominal-B type homeodomain transcription factors AHRR AHR-arnt heterodimers and AHR-related factors MAZF AIRE Autoimmune regulatory element binding factor MEF2 AP1R MAF and AP1 related factors MOKF AP2F Activator protein 2 MYBL AP4R AP4 and related proteins MYOD ARID AT rich interactive domain factor MYT1 BCDF Bicoid-like homeodomain transcription factors MZF1 BCL6 POZ domain zinc finger expressed in B-Cells NEUR BRAC Brachyury gene, mesoderm developmental factor NF1F BRN5 Brn-5 POU domain factors NFAT BRNF Brn POU domain factors NFKB CAAT CCAAT binding factors NKX6 CART Cart-1 (cartilage homeoprotein 1) NKXH CDEF Cell cycle regulators: Cell cycle dependent element NOLF CDXF Vertebrate caudal related homeodomain protein NR2F CEBP Ccaat/Enhancer Binding Protein NRF1 CIZF CAS interating zinc finger protein NRSF CLOX CLOX and CLOX homology (CDP) factors OCT1 CP2F CP2-erythrocyte Factor related to drosophila Elf1 OVOL CREB cAMP-responsive element binding proteins PARF CSEN Calsenilin, presenilin binding protein, EF hand transcription factor PAX2 CTCF and BORIS gene family, transcriptional regulators with 11 highly PAX3 CTCF conserved zinc finger domains PAX6 Homolog to deformed epidermal autoregulatory factor-1 from D. PAX8 DEAF melanogaster PBXC DMRT DM domain-containing transcription factors PDX1 E2FF E2F-myc activator/cell cycle regulator PIT1 Ubiquitous GLI - Krueppel like zinc finger involved in cell cycle PLAG E4FF regulation PRDF EBOX E-box binding factors PREB EGRF EGR/nerve growth factor induced protein C & related factors PTF1 ETSF Human and murine ETS1 factors RBPF EVI1 EVI1-myleoid transforming protein RORA FAST FAST-1 SMAD interacting proteins RP58 FKHD Fork head domain factors RU49 FXRE Farnesoid X - activated receptor response elements RUSH GATA GATA binding factors GCMF Chorion-specific transcription factors with a GCM DNA binding domain RXRF GFI1 Growth factor independence transcriptional repressor SIXF GLIF GLI zinc finger family SNAP GREF Glucocorticoid responsive and related elements SORY GRHL Grainyhead-like transcription factors SP1F GTBX GT box SPZ1 GZF1 GDNF-inducible zinc finger gene 1 SRFF HAML Human acute myelogenous leukemia factors STAT HAND Twist subfamily of class B bHLH transcription factors TALE HBOX Homeobox transcription factors TCFF HEAT Heat shock factors TEAF HESF Vertebrate homologues of enhancer of split complex TF2B HIFF Hypoxia inducible factor, bHLH/PAS protein family TF2D HMTB Human muscle-specific Mt binding site VSMA HNF1 Hepatic Nuclear Factor 1 VTBP HNF6 Onecut homeodomain factor HNF6 XBBF HOMF Homeodomain transcription factors XCPE HOXC HOX - PBX complexes HOXF Paralog hox genes 1-8 from the four hox clusters A, B, C, D YBXF HOXH HOX - MEIS1 heterodimers HZIP Homeodomain-leucine zipper transcription factors IKRS Ikaros zinc finger family YY1F INRE Core promoter initiator elements ZBPF INSM Insulinoma associated factors ZFHX IRFF Interferon regulatory factors ZFXY KLFS Krueppel like transcription factors LEFF LEF1/TCF ZNFP Lim homeodomain factors Myc associated zinc fingers MEF2, myocyte-specific enhancer binding factor Mouse Krueppel like factor Cellular and viral myb-like transcriptional regulators Myoblast determining factors MYT1 C2HC zinc finger protein Myeloid zinc finger 1 factors NeuroD, Beta2, HLH domain Nuclear factor 1 Nuclear factor of activated T-cells Nuclear factor kappa B/c-rel NK6 homeobox transcription factors NKX homeodomain factors Neuron-specific-olfactory factor Nuclear receptor subfamily 2 factors Nuclear respiratory factor 1 Neuron-restrictive silencer factor Octamer binding protein OVO homolog-like transcription factors PAR/bZIP family PAX-2 binding sites PAX-3 binding sites PAX-4/PAX-6 paired domain binding sites PAX-2/5/8 binding sites PBX1 - MEIS1 complexes Pancreatic and intestinal homeodomain transcription factor GHF-1 pituitary specific pou domain transcription factor Pleomorphic adenoma gene Positive regulatory domain I binding factor PREB core-binding element Pancreas transcription factor 1, heterotrimeric transcription factor RBPJ - kappa v-ERB and RAR-related orphan receptor alpha RP58 (ZFP238) zinc finger protein Zinc finger transcription factor RU49, zinc finger proliferation 1 - Zipro1 SWI/SNF related nucleophosphoproteins with a RING finger DNA binding motif RXR heterodimer binding sites Sine oculis (SIX) homeodomain factors snRNA-activating protein complex SOX/SRY-sex/testis determinig and related HMG box factors GC-Box factors SP1/GC Testis-specific bHLH-Zip transcription factors Serum response element binding factor Signal transducer and activator of transcription TALE homeodomain class recognizing TG motifs TCF11 transcription factor TEA/ATTS DNA binding domain factors RNA polymerase II transcription factor II B General transcription factor IID, GTF2D Vertebrate SMAD family of transcription factors Vertebrate TATA binding protein factor X-box binding factors Activator-, mediator- and TBP-dependent core promoter element for RNA polymerase II transcription from TATA-less promoters Y-box binding transcription factors, multifunctional proteins involved in transcriptional and translational regulation, mRNA splicing, DNA replication and repair Activator/repressor binding to transcription initiation site Zinc binding protein factors Two-handed zinc finger homeodomain transcription factors Zfx and Zfy - transcription factors implicated in mammalian sex determination Zinc finger proteins