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Transcript
Persistence of lymphoblasts in bone marrow on day 15 and
days 22 to 25 of remission induction predicts a dismal
treatment outcome in children with acute lymphoblastic
leukemia
by John T. Sandlund, Patricia L. Harrison, Gaston Rivera, Frederick G. Behm, David
Head, James Boyett, Jeffrey E. Rubnitz, Amar Gajjar, Susana Raimondi, Raul
Ribeiro, Melissa Hudson, Mary Relling, William Evans, and Ching-Hon Pui
Blood
Volume 100(1):43-47
July 1, 2002
©2002 by American Society of Hematology
Day 15 estimates of EFS in patients with ALL.(A) Kaplan-Meier estimate of EFS according to the
percentage of lymphoblasts on the day 15 BM in studies XI and XII combined.
John T. Sandlund et al. Blood 2002;100:43-47
©2002 by American Society of Hematology
Day 22 estimates of EFS.(A) Kaplan-Meier estimates of EFS according to the percentage of
lymphoblasts in studies XI and XII. (B) Kaplan-Meier estimates of EFS by day 22 BM blast
percentage in study XI. (C) Kaplan-Meier estimates of EFS by day 22 BM blast pe...
John T. Sandlund et al. Blood 2002;100:43-47
©2002 by American Society of Hematology
Kaplan-Meier estimates of EFS for patients with no lymphoblasts on day 15, for those with
lymphoblasts on day 15 but with no lymphoblasts on day 22, and for those with lymphoblasts on
day 22.
John T. Sandlund et al. Blood 2002;100:43-47
©2002 by American Society of Hematology