Download Clinical factors influencing hospitalization in IBD patients Authors

Clinical factors influencing hospitalization in IBD patients
Authors & Coauthors: Dr. Bogdan Mazilu, Institutul de Gastroenterologie ș i
Hepatologie, Iaș i
Dr. Roxana Maxim, Institutul de Gastroenterologie ș i Hepatologie,
Iaș i
Dr. Conf. Alina Pleș a, Institutul de Gastroenterologie ș i Hepatologie,
Iaș i
Abstract:
Background and Aims
We aimed to identify clinical factors influencing hospitalization in a cross-sectional
study including patients diagnosed with IBD (Inflammatory bowel disease)
hospitalized in the year 2014.
Methods
A total of 138 patients with IBD where hospitalized in the Institute of Gastroenterology and
Hepatology of St. Spiridon Hospital in Iasi in 2014. A number of 36 patients required more
than one admission, summing a total of 185 IBD admissions. Our study included 41 patients
with CD(Crohn disease), 91 with UC (ulcerative colitis) and 6 patients with undifferentiated
colitis.
Results
Over the course of the year, our patients have accumulated a total of 1354 days (3.7 years)
of hospitalization. Regarding the demographic features of our case population, 84 (61%)
were male, 92 (67%) were from urban regions, 85 (62%) were of 40 years or older. UC had
on average longer hospitalization (7.1 days/pacient) compared to CD (6.3
days/pacient).Correlating disease activity with average hospitalization period, 33% of the
cases where evaluated with moderate activity scores with an average of 5 to 9 days of
admission, followed by 26% cases of severe activity with 10 to 31 days of admission. Disease
localization associated ileocolic CD(23, 56%) with longer hospitalizations, followed by ileal
forms(10, 24%), while UC showed almost equal left-side disease(31, 44%) and extensive
disease(28, 40%), but with longer average hospitalization for the later (8.86 days compared
to 7.03) Out of 32 intestinal complications, stenosing IBD was more frequent (66%) than the
fistulizing form(50%) with hospitalization between 5 and 20 days. Association of CDI
(Clostridium difficile infection) increased average patient admission from 6.3 to 7.5 in CD and
from 7.1 to 9.57 in UC.
Conclusion
Clinical and demographic features may influence negatively the average hospital admission
for IBD patients, imposing the need for careful approach of preventable risk factors.
Keywords: inflammatory bowel disease, hospitalization.