Download Purified anti-HIV TAT Antibody (Previously Covance

Version: 3
Revision Date: 07/21/2016
Purified anti-HIV TAT Antibody (Previously Covance catalog#
MMS-116P)
Catalog# / Size
919001 / 250 µl
Clone
AC11.AE12 (See other available formats)
Other Names
HIV TAT
Previously
Covance Catalog# MMS-116P
Isotype
Mouse IgG1
Ave. Rating
★★★★★ 0 reviews
Description
The HIV-1 TAT (transactivator of transcription) gene codes for a 14 kD
protein and is vital for HIV-1 transcription. After infection, TAT is one of the
first proteins expressed after HIV has taken over the host’s machinery. TAT is
a RNA binding protein that recognizes the TAR (Transactivator Response
Element) sequence found in the HIV-1 RNA molecule. It is also needed for
the recruitment of the host positive transcription elongation factor b (pTEFb). In neuron cells, TAT has been linked to progressive neuronal
deregulation, HIV-Associated Neurocognitive Disorders and accelerating
brain aging.
Western blot analysis of recombinant HIVTAT protein. Lane 1: MW Marker; Lane 2:
50ng of protein; Lane 3: 100ng of protein.
Reactivity
1-37 aa of HIV TAT Tag
Immunogen
This antibody was generated against full-length HIV TAT protein.
Formulation
Phosphate-buffered solution + 0.03% Thimerosal.
Preparation
The antibody was purified by affinity chromatography.
Concentration
1 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C. Please note the
storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You
can also check your vial or your CoA to find the most accurate storage condition for this
antibody.
Application
WB
Recommended Usage
Each lot of this antibody is quality control tested by Western blotting.
The optimal working dilution should be determined for each specific assay condition.
• WB: 1:1,000*
Application Notes
This antibody is effective in immunoblotting (WB).
*Predicted MW = 11 kD
The epitope is contained in the first 37 amino acids of the protein.
RRID
AB_2565207 (BioLegend Cat. No. 919001)
Antigen Details
Gene ID
NA
UniProt
View information about HIV TAT on UniProt.org
Documentation
Technical data sheet
Certificate of Analysis
Safety Data Sheet
Related Protocols
Western Blotting Protocol
Related FAQs
There are no FAQs for this product.
Related Categories
Antibodies and More > Cell Biology > Antigens A-Z > HIV TAT >
Antibodies and More > Cell Biology > Bacterial Proteins and Toxins > HIV TAT >
For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or
other violations that may occur with the use of our products.
*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website,
www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or
used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties
without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited
Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or
animal diagnostic, therapeutic or commercial use.
BioLegend Inc., 9727 Pacific Heights Blvd, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587