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Role of Blood Clot Formation on Early Edema Development After Experimental Intracerebral Hemorrhage by Guohua Xi, Kenneth R. Wagner, Richard F. Keep, Ya Hua, Gabrielle M. de Courten-Myers, Joseph P. Broderick, Thomas G. Brott, and Julian T. Hoff Stroke Volume 29(12):2580-2586 December 1, 1998 Copyright © American Heart Association, Inc. All rights reserved. A and B, Representative coronal sections from pig brains frozen in situ at 4 hours (A) and 24 hours (B) after unheparinized blood infusions into the frontal white matter. Guohua Xi et al. Stroke. 1998;29:2580-2586 Copyright © American Heart Association, Inc. All rights reserved. Quantitation of hematoma and edema volumes in heparinized (n=6) and unheparinized (n=6) blood-infused pig brains frozen between 1 and 24 hours after blood infusion. Guohua Xi et al. Stroke. 1998;29:2580-2586 Copyright © American Heart Association, Inc. All rights reserved. Brain water contents in rats at 24 hours after infusion of 50 μL saline or heparinized blood or blood. Guohua Xi et al. Stroke. 1998;29:2580-2586 Copyright © American Heart Association, Inc. All rights reserved. Brain sodium (A) and potassium ion (B) contents at 24 hours after infusion of 50 μL saline or heparinized blood or blood in rats. Guohua Xi et al. Stroke. 1998;29:2580-2586 Copyright © American Heart Association, Inc. All rights reserved. Brain water content in rats 24 hours after infusion of 60 mL saline or thrombin+saline or thrombin+heparin. Guohua Xi et al. Stroke. 1998;29:2580-2586 Copyright © American Heart Association, Inc. All rights reserved. Brain sodium (A) and potassium ion (B) contents 24 hours after infusion of 60 μL saline or thrombin+saline or thrombin+heparin in rats. Guohua Xi et al. Stroke. 1998;29:2580-2586 Copyright © American Heart Association, Inc. All rights reserved.