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(Reproduced, with permission, from Shendure J, Ji H. Next-generation DNA sequencing. Nat Biotechnol. 2008;26(10):1135-1145.) Source: Methods, Laboratory Medicine: The Diagnosis of Disease in the Clinical Laboratory Citation: Laposata M. Laboratory Medicine: The Diagnosis of Disease in the Clinical Laboratory; 2014 Available at: http://mhmedical.com/ Accessed: August 11, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved