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Biographical Sketch for Lingyun Liu
Dept. of Chemical and Biomolecular. Engineering
University of Akron, Akron, OH 44325-3906
Phone: (330) 972-6187; Fax: (330) 972-5856; Email: [email protected]
PROFESSIONAL PREPARATION
University of Washington
Bioengineering
Southeast University
Biomedical Engineering
Southeast University
Biomedical Engineering
Ph.D. 2007
M.S. 2000
B.S. 1998
APPOINTMENTS
2007-present
University of Akron
Assistant Professor Dept of Chemical and Biomolecular Engr
2000-2006
1998-2000
University of Washington
Research Assistant Department of Bioengineering
(Advisor: Buddy Ratner & Shaoyi Jiang)
Southeast University
Research Assistant Department of Biomedical Engineering
(Advisor: Zuhong Lu)
RESEARCH INTEREST
Biointerfaces, Biomaterials, Tissue Engineering, Biosensors, Surface Modification
and Characterization, Nonfouling Materials, Drug Delivery, Nanofibers, Nanoparticles,
BioMEMS and Microfabrications, Stem Cells
REPRESENTATIVE PUBLICATIONS
1. L. Y. Liu, G. Cheng, T. Chao, B. D. Ratner, E. H. Sage and S. Y. Jiang, Reduced
foreign body reaction to implanted biomaterials by surface treatment with
oriented osteopontin, Journal of Biomaterials-polymer edition (in press, 2008)
2. Y. Chang, W. L. Chu, W. Y. Chen, J. Zheng, L. Y. Liu, R. C. Ruaan and A.
Higuchi, A surface plasmon resonance study of plasma protein repulsion from
self-assembled poly(ethylene oxide) triblock copolymer surfaces, to be submitted
(2008)
3. A. D. Taylor, L. Y. Liu, J. G. Ghosh, J. I. Clark and S. Y. Jiang, Kinetics studies
of the interaction between molecular chaperone B and substrate proteins by
surface plasmon resonance, to be submitted (2008)
4. L. Y. Liu, B. D. Ratner, E. H. Sage and S. Y. Jiang, Endothelial cell migration on
surface-density gradients of fibronectin, VEGF, or both proteins, Langmuir, 23,
11168-11173 (2007)
5. L. Y. Liu, C. L. Qin, W. T. Butler, B. D. Ratner and S. Y. Jiang, Controlling the
orientation of bone osteopontin to modulate osteoblast adhesion via its specific
binding with collagen I, Journal of Biomedical Materials Research A, 80A, 102110 (2007)
6. S. F. Chen, L. Y. Liu and S. Y. Jiang, Strong resistance of
oligo(phosphorylcholine) self-assembled monolayers to protein adsorption,
Langmuir, 22(6), 2418-2421 (2006)
7. L. Y. Liu, J. G. Ghosh, J. I. Clark and S. Y. Jiang, Studies of B crystallin subunit
dynamics by surface plasmon resonance, Analytical Biochemistry, 350(2), 186195 (2006)
8. L. Y. Liu, S. F. Chen, C. M. Giachelli, B. D. Ratner and S. Y. Jiang, Controlling
osteopontin orientation on surfaces to modulate endothelial cell adhesion, Journal
of Biomedical Materials Research A, 74A(1), 23-31 (2005)
9. V. Lockhart, L. Y. Liu and S. Y. Jiang, Interactions between secreted protein,
acidic and rich in cysteine (SPARC), and type I collagen identified by surface
Plasmon resonance biosensor, Journal of Undergraduate Research in
Bioengineering, 4(2), 69-74 (2004)
10. S. F. Chen, L. Y. Liu, J. Zhou and S. Y. Jiang, Controlling antibody orientation on
charged self-assembled monolayers, Langmuir, 19(7), 2859-2864 (2003)
PRESENTATIONS
1. Lingyun Liu, Control of Cell-Protein-Surface Interactions for Biomaterial and
Biosensor Applications, Department of Chemical and Biomolecular Engineering,
Ohio University, May 13, 2008, Athens, OH. Invited Seminar
2. Lingyun Liu, Control of Cell-Protein-Surface Interactions for Biomaterial and
Biosensor Applications, Akron General Medical Center, Apr. 10, 2008, Akron,
OH. Invited Seminar
3. Lingyun Liu, Control of Protein-Surface, Protein-Protein and Cell-Protein
Interactions for Biomaterial and Biosensor Applications, Department of Polymer
Engineering, University of Akron, Feb. 29, 2008, Akron, OH. Invited Seminar
4. Lingyun Liu, Engineering Biointerfaces for Biomaterial, Tissue Engineering
and Biosensor Applications, Oct. 24, 2007, Society of Women in Engineering,
University of Akron, Akron, OH. Invited Seminar
5. Zheng Zhang, Timothy Chao, Lingyun Liu and Shaoyi Jiang, Nonfouling and
responsive zwitterionic hydrogels with immobilized proteins and improved
mechanical strength, Materials Research Society Fall Meeting, Nov. 27-Dec. 1,
2006, Boston, Maryland. Poster
6. Zheng Zhang, Lingyun Liu, Timothy Chao and Shaoyi Jiang, Nonfouling and
responsive zwitterionic hydrogels with immobilized proteins and improved
mechanical properties, Annual Meeting of American Institute of Chemical
Engineers, Nov. 12-17, 2006, San Fransisco, California. Oral presentation
7. Mattew Bernards, Lingyun Liu, and Shaoyi Jiang, Mechanisms for controlling
protein orientation, Annual Meeting of American Institute of Chemical
Engineers, Nov. 12-17, 2006, San Fransisco, California. Poster
8. Lingyun Liu, Hua Wang, Buddy D. Ratner, E. Helene Sage, and Shaoyi Jiang,
Capillary-like differentiation of endothelial cells by topographic patterns,
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gradient surfaces, or oriented proteins, Society for Biomaterials 2006 Annual
Meeting, Apr. 26-29, 2006, Pittsburgh, Pennsylvania. Oral presentation
Lingyun Liu, Hua Wang, Buddy D. Ratner, E. Helene Sage, and Shaoyi Jiang,
Capillary-like differentiation of endothelial cells on microgrooved or gradient
surfaces, Society for Biomaterials 2006 Annual Meeting, Apr. 26-29, 2006,
Pittsburgh, Pennsylvania. Poster
Mattew Bernards, Lingyun Liu, Buddy D. Ratner, and Shaoyi Jiang, Controlling
and probing protein orientation/conformation for biomaterial applications,
Society for Biomaterials 2006 Annual Meeting, Apr. 26-29, 2006, Pittsburgh,
Pennsylvania. Oral presentation
Mattew Bernards, Lingyun Liu, Buddy D. Ratner, and Shaoyi Jiang, Controlling
protein orientation to modulate cellular adhesion, Society for Biomaterials 2006
Annual Meeting, Apr. 26-29, 2006, Pittsburgh, Pennsylvania. Poster
Shengfu Chen, Jie Zheng, Fuchen Yu, Qiuming Yu, Yi He, Lingyun Liu and
Shaoyi Jiang, Insights into nonfouling properties of zwitterionic materials,
Society for Biomaterials 2006 Annual Meeting, Apr. 26-29, 2006, Pittsburgh,
Pennsylvania. Oral presentation
Lingyun Liu, Chunlin Qin, Williams Butler, Buddy D. Ratner and Shaoyi Jiang,
Controlling the orientation of bone osteopontin via its specific binding with
collagen I to modulate osteoblast adhesion, University of Washington
Engineered Biomaterials-NSF Site Visit Poster Session, May 26-27, 2005,
Seattle, Washington. Poster
Lingyun Liu, Hua Wang, Lingyan Li, Buddy D. Ratner and Shaoyi Jiang,
Controlling cell adhesion/spreading by modulating osteopontin orientation on
charged SAMs, Annual Meeting of American Institute of Chemical Engineers,
Nov. 7-12, 2004, Austin, Texas. Oral presentation
Lingyun Liu, Shengfu Chen, Buddy D. Ratner and Shaoyi Jiang, Control of
osteopontin behavior on surfaces for cell adhesion, 50th International Symposium
of American Vacuum Society, Nov. 2-7, 2003, Baltimore, Maryland. Poster
Lingyun Liu, Shengfu Chen, Buddy D. Ratner and Shaoyi Jiang, Controlling
osteopontin behavior on surfaces for endothelial cell adhesion, Surfaces in
Biomaterials Foundation - Biointerface 2003, Oct. 22-24, 2003, Savannah,
Georgia. Poster (David J. Lee Student Poster Award)
Shengfu Chen, Lingyun Liu and Shaoyi Jiang, Oriented immobilization of antihuman chronic gonadotropin for biosensor applications, 49th International
Symposium of American Vacuum Society, Nov. 4-8, 2002, Denver, Colorado.
Poster