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Supplemental Data Table 1. Univariate and multivariate analysis for disease free interval and overall survival of the FFPEs tissues of metastasis
verified breast cancer patients.
Univariate analysis
Multivariate analysis
Disease Free Interval
Hazard Ratio (95% Cl)
p-valuea
Estrogen receptor
0.685 (0.291-1.616)
0.394
Progesterone receptor
0.711 (0.293-1.724)
0.451
HER-2
0.751 (0.287-1.984)
0.554
miR-21 up vs down
1.846 (1.016-3,355)
0.044
miR-200c up vs down
0.881 (0.487-.,854)
0.881
miR-146α up vs down
2.696 (1.143-6.357)
0.025
miR-210 up vs down
1.429 (0.693-2.949)
0.334
Overall Survival
Hazard Ratio (95% Cl)
p-valuea
Estrogen receptor
0.493 (0.158-1.537)
0.223
Progesterone receptor
0.703 (0.225-2.195)
0.703
HER-2
1.119 (0.288-4.347)
0.871
Hazard Ratio (95% Cl)
p-valuea
0.701 (0.350-1.405)
0.317
2.969 (1.231-7.157)
0.015
a
miR-21 up vs down
2.095 (0.902-4.865)
0.085
miR-200c up vs down
1.209 (0.484-3.024)
0.684
miR-146α up vs down
1.122 (0.345-3.654)
0.848
miR-210 up vs down
1.036 (0.365-2.943)
0.946
Cox regression analysis
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