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Peripheral nervous system Spinal nerves ALR © Anne LeRoy 30.9.2015 © Anne LeRoy 30.9.2015 © Anne LeRoy 30.9.2015 Parts of the nervous system • Central nervous system ▫ Spinal cord ▫ Brain Brain stem (medulla oblongata, pons, mesencephalon) Cerebellum Diencephalon Telencephalon • Peripheral nervous system ▫ Spinal nerves ▫ Cranial nerves ▫ Autonomic nerves Sympathetic Parasympathetic © Anne LeRoy 30.9.2015 Terminology • • • • • neuroglia neuron nervous fiber nerve ganglion, nucleus © Anne LeRoy 30.9.2015 Cells of the nervous system • neurons • neuroglia © Anne LeRoy 30.9.2015 Neuroglia • CNS: ▫ ▫ ▫ ▫ oligodendroglia astrocytes ependymal cells microglia • PNS ▫ satellite cells ▫ Schwann cells © Anne LeRoy 30.9.2015 © Anne LeRoy 30.9.2015 Neuron types • multipolar ▫ motor fibers ▫ autonomic fibers Multipolar neurons • pseudounipolar ▫ somatic sensory fibers • bipolar ▫ retina, ggl of the vestibulocochlear nerve, olfactory epithelium © Anne LeRoy 30.9.2015 © Anne LeRoy 30.9.2015 Nervous fiber • axon • neurolemma Schwann cells ▫ producing myelin ▫ not producing myelin © Anne LeRoy 30.9.2015 Types of fibers • Afferent = sensory fibers originate on receptors in the periphery ▫ somatic sensory fibers exteroceptive and proprioceptive sensations ▫ visceral sensory fibers • Efferent = motor fibers ▫ somatic motor fibers to skeletal muscles ▫ visceral motor fibers to smooth and cardiac muscles, glands © Anne LeRoy 30.9.2015 „Nerves“ • nervous fibers ▫ axon ▫ neurolemma (Schwann cells – producing myelin or not) • connective tissue ▫ endoneurium, perineurium, epineurium • vasa nervorum © Anne LeRoy 30.9.2015 Ganglia and nuclei = collection of neuron cell bodies ganglion: outside the CNS - sensory (DRG) - autonomic - sympathetic (tr. sympaticus) - parasympathetic (periphery) nucleus: in the CNS Dorsal root ganglion from a chicken embryo © Anne LeRoy 30.9.2015 Spinal segments 31 segments: • C1-C8 • T1-T12 • L1-L5 • S1-S5 • Co © Anne LeRoy 30.9.2015 Macroscopy of the branching of the spinal nerve © Anne LeRoy 30.9.2015 © Anne LeRoy 30.9.2015 Posterior vs anterior rami Rami posteriores Rami anteriores Doesn‘t form plexuses Forms the major somatic plexuses Both sensory and motor fibers Both sensory and motor fibers Sensory: skin medially close to the spine Sensory: skin in the rest of the body Motor: epaxial muscles Motor: hypaxial muscles © Anne LeRoy 30.9.2015 Epaxial vs hypaxial muscles © Anne LeRoy 30.9.2015 © Anne LeRoy 30.9.2015 Rami posteriores nervorum spinalium C1: n. suboccipitalis m. rectus capitis post. mj. m. rectus capitis post. mi. m. obliquus capitis sup. m. obliquus capitis inf. C2: n. occipitalis major C3: n. occipitalis tertius L1-L3: nn. clunium superiores S1-S3: nn. clunium medii © Anne LeRoy 30.9.2015 interauricular line Rami anteriores nervorum spinalium • Cervical plexus (C2-C4) • Plexus brachialis (C5-T1) • rami anteriores nn. thoracicum (T1-T12) • Pleus lumbalis (T12-L4) • Plexus sacralis (L4-S1) • Plexus coccygeus (S5-Co) © Anne LeRoy 30.9.2015 © Anne LeRoy 30.9.2015 Plexus cervicalis – sensory branches © Anne LeRoy 30.9.2015 Punctum nervosum /Jonáš/ ▫ ▫ ▫ ▫ n. occipitalis minor n. auricularis magnus n. transversus coli nn. supraclaviculares © Anne LeRoy 30.9.2015 © Anne LeRoy 30.9.2015 © Anne LeRoy 30.9.2015 Plexus cervicalis – motor branches © Anne LeRoy 30.9.2015 © Anne LeRoy 30.9.2015 Plexus cervicalis – inervated muscles • mm. scaleni ant. + med. – pl. cervicalis + brachialis • mm. infrahyoidei – ansa cervicalis prof. • m. longus colli - pl. cervicalis + brachialis • m. longus capitis • m. rectus capitis ant. + lat • m. sternocleidomastoideus + m. trapezius – ansa Maubraci © Anne LeRoy 30.9.2015 Plexus cervicalis – n. phrenicus C3-C5 = both sensory and motor motor: diaphragm sensory: pleura mediastinalis + diaphragmatica, pericardium, peritoneum parietale (partially), thymus (Cruchet‘s nerve), gallbladder © Anne LeRoy 30.9.2015 © Anne LeRoy 30.9.2015 © Anne LeRoy 30.9.2015 Paralysis of the diaphragm © Anne LeRoy 30.9.2015 Plexus brachialis • truncus (trunk) superior (C4+C5+C6) medius (C7) inferior (C8+T1) • fasciculus (cord) lateralis medialis posterior • pars supraclavicularis • pars infraclavicularis © Anne LeRoy 30.9.2015 © Anne LeRoy 30.9.2015 Brachial plexus injuries © Anne LeRoy 30.9.2015 plexus brachialis – pars supraclavicularis • • • • n. dorsalis scapulae n. thoracicus longus n. subclavius n. suprascapularis ▫ incisura scapulae ▫ incisura spinoglenoidalis • n. thoracodorsalis © Anne LeRoy 30.9.2015 n. thoracicus longus injury „Scapula alata“ © Anne LeRoy 30.9.2015 © Anne LeRoy 30.9.2015 plexus brachialis – pars infraclavicularis • fasciculus medialis ▫ ▫ ▫ ▫ n. ulnaris n. cutaneus antebrachii med. n. cutaneus brachii med. n. medianus • fasciculus lateralis ▫ n. musculocutaneus ▫ n. medianus • fasciculus posterior ▫ n. axillaris ▫ n. radialis • nn. pectorales • n. subscapularis © Anne LeRoy 30.9.2015 Entrapment syndromes = compression of peripheral nerves in anatomical „tunnel“ regions, where they are suceptible to injury. paresthesia, anesthesia in the area nervina of the injuried nerve palsy – according to the motor inervation of the injuried nerve Tinel‘s sign © Anne LeRoy 30.9.2015 n. radialis C5-C8 • sulcus nervi radialis • behind the head of radius • canalis supinatorius (r. prof) ▫ Frohse‘s arcade -> wrist drop „Saturday night‘s palsy“ © Anne LeRoy 30.9.2015 n. axillaris – C5-C6 • foramen humerotricipitale -> „flat shoulder deformity“ – increased risk of luxation © Anne LeRoy 30.9.2015 n. medianus – C5-T1 • • • • ligament of Struthers lacertus fibrosus canalis pronatorius canalis carpi • -> „preaching hand“ ape hand deformity • carpal tunnel syndrome © Anne LeRoy 30.9.2015 © Anne LeRoy 30.9.2015 n. ulnaris – C8-T1 • claw hand • Froment‘s sign © Anne LeRoy 30.9.2015 Rami anteriores nervorum thoracicorum • nn. intercostales I-XI • n. subcostalis © Anne LeRoy 30.9.2015 Intercostal nerves – motor branches nn. intercostales VII-XII • rr. musculares: ▫ ▫ ▫ ▫ ▫ ▫ ▫ ▫ mm. intercostales m.transversus thoracis m. serratus post. m. obliquus abdominis ext. m. obliquus abdominis int. m. rectus abdominis m. transvertsus abdominis m. pyramidalis © Anne LeRoy 30.9.2015 Intercostal nerves – sensory branches • nn. cutanei laterales ▫ rr. mammarii laterales ▫ nn. intercostobrachiales (IC-II) • nn. cutanei anteriores (terminal branches of IC I-VI) ▫ rr. mammarii mediales • rr. pleurales et peritoneales „défense musculaire“ © Anne LeRoy 30.9.2015 © Anne LeRoy 30.9.2015 Plexus lumbalis T12-L4 • „ I, I Get Laid On Fridays“ • • • • • • n. Iliohypogastricus – T12-L1 n. Ilioinguinalis – L1 n. Genitofemoralis – L1-L2 n. cutaneus femoris Lateralis – L2-L3 n. Obturatorius – L2-L4 n. Femoralis – L2-L4 Nerve Motor Sensory n. Iliohypogastricus m. Transversus abd. m. Obliquus int. abd. Sup. to©crista iliaca Anne LeRoy 30.9.2015 and lig. inguinale n. Ilioinguinalis m. Transversus abd. m. Obliquus int. abd. Scrotum Labia majora n. genitofemoralis r. Genitalis n. genitofemoralis Topography Canalis inginalis Through m. psoas major m. Cremaster Scrotun Labia majora r. Femoralis n. genitofemoralis Inf. to lig. inginale Lacuna vasorum n. Cutaneus femoris lateralis Lateral part of the thigh Lacuna musculorum n. Femoralis m. Iliopsoas Anterior group of the thigh rr. Cutanei ant. femoris n. Saphenus Lacuna musculorum Trigonum femorale Canalis adductorius n. Obturatorius Medial group of the thigh Medial part of the thigh Canalis obturatorius © Anne LeRoy 30.9.2015 Palsies • n. femoralis • n. obturatorius: weakened adduction and medial rotation (pregnancy) • n. cutaneus femoris lateralis: meralgia parestetica © Anne LeRoy 30.9.2015 Plexus sacralis (L4-S4) • • • • • n. gluteus sup. – L4-S1 n. gluteus inf. – L5-S2 n. cutaneus femoris post. – S1-S3 n. ischiadicus – L4-S3 n. pudendus – S2-S4 n. pudendus • Somatic motor: ▫ pelvic floor ▫ perineal muscles • visceral motor ▫ corpora cavernosa ▫ corpora spongiosa • sensory ▫ perianal region ▫ scrotum/labia majora ▫ penis/clitoris • Topography ▫ ▫ ▫ ▫ foramen infrapiriforme foramen ischiadicum minus fossa ischioanalis canalis pudendalis Alcocki © Anne LeRoy 30.9.2015 © Anne LeRoy 30.9.2015 © Anne LeRoy 30.9.2015 Plexus coccygeus S5-Co • Motor: helps in the inervation of the pelvic floor • Sensory: nn. anococcygei (hurts in coccygeal fractures) Areae radiculares Areae nervinae © Anne LeRoy 30.9.2015 © Anne LeRoy 30.9.2015