Download Powerpoint - Blood Journal

Survey
yes no Was this document useful for you?
   Thank you for your participation!

* Your assessment is very important for improving the work of artificial intelligence, which forms the content of this project

page
1
page
2
page
3
page
4
page
5
page
6
page
7
page
8
Document related concepts
no text concepts found
Transcript 
Novel role for EKLF in megakaryocyte lineage commitment
by Pilar Frontelo, Deepa Manwani, Mariann Galdass, Holger Karsunky, Felix
Lohmann, Patrick G. Gallagher, and James J. Bieker
Blood
Volume 110(12):3871-3880
December 1, 2007
©2007 by American Society of Hematology
EKLF expression during hematopoietic cell differentiation.
Pilar Frontelo et al. Blood 2007;110:3871-3880
©2007 by American Society of Hematology
EKLF induction negatively affects megakaryocyte formation during embryoid body (EB)
differentiation.
Pilar Frontelo et al. Blood 2007;110:3871-3880
©2007 by American Society of Hematology
Megakaryocyte markers are inhibited during EB differentiation on OP9 cells after EKLF
induction.
Pilar Frontelo et al. Blood 2007;110:3871-3880
©2007 by American Society of Hematology
EKLF induction affects erythroid differentiation.
Pilar Frontelo et al. Blood 2007;110:3871-3880
©2007 by American Society of Hematology
EKLF-null fetal liver cells yield a greater expansion of megakaryocytes.
Pilar Frontelo et al. Blood 2007;110:3871-3880
©2007 by American Society of Hematology
Expression of selected genes after EKLF induction during EB differentiation.
Pilar Frontelo et al. Blood 2007;110:3871-3880
©2007 by American Society of Hematology
EKLF, Fli1, and GATA1 expression during MEP differentiation and repression of Fli1 by EKLF.
Cell populations were sorted as detailed in Table S1 and monitored for EKLF, Fli1, and GATA1
expression by quantitative RT-PCR.
Pilar Frontelo et al. Blood 2007;110:3871-3880
©2007 by American Society of Hematology
Related documents