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Mast cell and macrophage chemokines CXCL1/CXCL2
control the early stage of neutrophil recruitment during
tissue inflammation
by Katia De Filippo, Anne Dudeck, Mike Hasenberg, Emma Nye, Nico van Rooijen,
Karin Hartmann, Matthias Gunzer, Axel Roers, and Nancy Hogg
Blood
Volume 121(24):4930-4937
June 13, 2013
©2013 by American Society of Hematology
Release of CXCL1-containing granules by mast cells in vivo after LPS stimulation.
Katia De Filippo et al. Blood 2013;121:4930-4937
©2013 by American Society of Hematology
CXCL1 in mast cells lacking TLR4 activity.
Katia De Filippo et al. Blood 2013;121:4930-4937
©2013 by American Society of Hematology
Mast cells release CXCR2-binding neutrophil chemoattractants.
Katia De Filippo et al. Blood 2013;121:4930-4937
©2013 by American Society of Hematology
The effect of blocking CXCL1/CXCL2 in vivo on the pattern of neutrophil recruitment.
Katia De Filippo et al. Blood 2013;121:4930-4937
©2013 by American Society of Hematology
The effect of macrophage depletion on neutrophil recuitment.
Katia De Filippo et al. Blood 2013;121:4930-4937
©2013 by American Society of Hematology
Neutrophil recruitment in Mcpt5-Cre+iDTR+ mast cell–depleted mice.
Katia De Filippo et al. Blood 2013;121:4930-4937
©2013 by American Society of Hematology
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