Download Figure1. Schematically depicted mitotic spindle in late metaphase

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Figure1. Schematically depicted mitotic spindle in late metaphase. The two spindle poles are located on the x1axis and the metaphase plate in the x2x3-plane. In budding yeast the kinetochores are more clustered around the
center of mass, rcm = (0, 0, 0), rather than dispersed on the metaphase plate, hence d ≈ 0. The kinetochore cluster
is then stretched along the x1 ≡ x axis and the spacing in this one-dimensional “lattice” is ∆1 ≡ ∆. Once the last
SC pair is bi-oriented and located at the metaphase plate, APC is activated by Cdc20 and the SC pairs
synchronously separated
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