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Association for Quality Assessment in
TDM and Clinical Toxicology
DRUGS OF ABUSE ROUND 2016.3A
Section of the Dutch Foundation for Quality
Assessment in Medical Laboratories
Deadline September 29
SKML nr.:
You can download this form: www.kkgt.nl: English version, scroll down till Drugs of Abuse and mail to [email protected]
Fictitious case, so please do a drug test also when this would not be normal policy in your lab:
Sample for a routine drug screening.
N.B. Methanol is used as solvent.
URINE SCREENING ROUND 2016.3A
OPIATES
COCAINE (benzoylecgonine)
AMPHETAMINES & ANALOGUES***
Amphetamine***
Methamphetamine***
MDA***
MDMA***
MDEA***
CANNABINOIDS (nor-∆9-THCCOOH)
METHADONE
EDDP
BENZODIAZEPINES
specificy calibrator
BARBITURATES
specificy calibrator
ETHANOL (g/l)
ETHYLGLUCURONIDE
Cut-off
μg/l
300
300
1000
1000
1000
1000
1000
1000
50
300
100
200
conc.
μg/l
method
code
E/N*
result**
N/ P/ NT
200
0,1
500
OTHER DRUGS
* E: enzymatic hydrolysis or N: nonenzymatic hydrolysis * *N: negative, P: positive or NT: not tested
***For amphetamine like components the tests is positive when the sum of the different components >1000 µg/l
Creatinine:
mmol/l.
This urine sample is: normal / dilute(d) / abnormal
Methodecode:
1. FPIA
6. RAPID ON-SITE TESTING
a. Axsym
f. Architect
a. Syva Rapid
j. Sure Screen
b. TDx/FLx
3. CEDIA
b. Micron
k. Quick Screen
c. FPIA, COBAS
4. KIMS(=online)
c. Triage
l. Bio-Rad
2. EIA
5. ELISA
d. Abusign
m. Dima
a. EMIT II
a. COZART
e. Accusign
n. Fastect II
b. EMIT II plus
b………….
f. Ontrack
o. Acon One Step
c. Beckman Coulter
g. Abuscreen
p. Testcard9
d. DRI
h. Druglab
q. ………
e. DST
i. SSD Rapid Drug Test
7. other immuno-chemical (semi) quantitative technics
COMMENT
Postbus 43100, 2504 AC Den Haag, Tel. (0031-70) 3 217 161,  www.kkgt.nl, E-mail: [email protected]
Association for Quality Assessment in
TDM and Clinical Toxicology
Section of the Dutch Foundation for Quality
Assessment in Medical Laboratories
DRUGS OF ABUSE ROUND 2016.3A
Cut-off
μg/l
URINE CONFIRMATION ROUND 2016.3A
Opiates:
Deadline September 29
6 MAM
15
MORPHINE
300
CODEINE
300
Cocaine :
BENZOYLECGONINE
150
Amphetamines:
AMPHETAMINE
500
METHYLAMPHETAMINE
500
MDA
500
MDMA
500
MDEA
500
Cannabis :
THC (1-nor-9-COOH-9-THC)
15
Methadone:
METHADONE
300
EDDP
100
Benzodiazepines
………………………
100
Barbiturates:
………………………
Ethanol (g/l):
ETHANOL
0,1
ETHYLGLUCURONIDE
500
Other drugs:
*
**
conc.
μg/l
method
code
SKML nr.:
result**
N/ P/ NT
E/N*
………………………
E: enzymatic hydrolysis or N: nonenzymatic hydrolysis
N: negative, P: positive or NT: not tested
Method code:
8. TLC
9. HPLC
10. GC
a. Toxilab
a. STIP/DAD
a. MS*
b. Conventional
b. UV/FLU/EC
b. FID/NPD/EC
c. HPTLC
c. MS*
c. ……………
d……………
d. ……………..
*: details van MS-detectie: …………………………………………………………………………………………..
Extraction : (liquid, pH, derivatized)
liquid /solid phase: ………………………………………………………………
derivatized
pH :…….
: no / yes with: ……………………………………………………………………
COMMENT:
Postbus 43100, 2504 AC Den Haag, Tel. (0031-70) 3 217 161,  www.kkgt.nl, E-mail: [email protected]
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