Download Guidelines on Ethic Review for Cell Lines Research

NUS Institutional Review Board (IRB)
Use of Extracted Teeth for Research
1. Existent left-over extracted teeth without identifiers.
Identifiers refer to information like names, initials, patient identification numbers or other
codes which would allow anyone to link samples (or data) either directly or indirectly to
subjects.
Research may be exempted from IRB review and informed consent may not be required.
The Principal Investigators would need to apply for Exemption from IRB review.
2. Existent left-over extracted teeth with identifiers.
This research requires expedited or full IRB review. Written informed consent is
required unless waived by the IRB. If the subject has granted permission for the use of
their tissues in research by signing the in-patient or out-patient treatment/admission
forms, further consent will normally be waived.
3. Prospective collection of extracted teeth without identifiers.
Prospective collection refers to the collection of extracted teeth after the research has
been approved by the IRB. Identifiers refer to information like names, initials, patient
identification numbers or other codes which would allow anyone to link samples (or data)
either directly or indirectly to subjects.
Research requires expedited or full IRB review and written informed consent is required
unless waived by the IRB.
4. Prospective collection of extracted teeth with identifiers.
Prospective collection refers to the collection of extracted teeth after the research has
been approved by the IRB. Identifiers refer to information like names, initials, patient
identification numbers or other codes which would allow anyone to link samples (or data)
either directly or indirectly to subjects.
Research requires expedited or full IRB review and written informed consent is required
unless waived by the IRB.
References:
OHRP Guidelines
Exempt from IRB review under 45 CFR 46.101.b
Waiver of Written informed consent under 45CFR46.116.d
IRB-GUIDE-009
Page 1 of 1
Version No: 1
Date of Revision: 01/08/04