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In utero transplantation of adult bone marrow decreases
perinatal lethality and rescues the bone phenotype in the
knockin murine model for classical, dominant
osteogenesis imperfecta
by Cristina Panaroni, Roberta Gioia, Anna Lupi, Roberta Besio, Steven A. Goldstein,
Jaclynn Kreider, Sergey Leikin, Juan Carlos Vera, Edward L. Mertz, Egon Perilli,
Fabio Baruffaldi, Isabella Villa, Aurora Farina, Marco Casasco, Giuseppe Cetta,
Antonio Rossi, Annalisa Frattini, Joan C. Marini, Paolo Vezzoni, and Antonella
Forlino
Blood
Volume 114(2):459-468
July 9, 2009
©2009 by American Society of Hematology
Distribution of eGFP+ cells in hematopoietic and nonhematopoietic tissues in recipient mice at 2
months posttransplantation.
Cristina Panaroni et al. Blood 2009;114:459-468
©2009 by American Society of Hematology
Engraftment analysis by direct cell counting.
Cristina Panaroni et al. Blood 2009;114:459-468
©2009 by American Society of Hematology
Real-time PCR evaluation of engraftment in different tissues of recipient mice.
Cristina Panaroni et al. Blood 2009;114:459-468
©2009 by American Society of Hematology
Collagen composition of extracellular matrix in bones from untreated and treated mutant mice.
Cristina Panaroni et al. Blood 2009;114:459-468
©2009 by American Society of Hematology
Representative pQCT scans in BrtlIV mice.
Cristina Panaroni et al. Blood 2009;114:459-468
©2009 by American Society of Hematology
Effect of IUT on geometry and mechanical properties of femurs.
Cristina Panaroni et al. Blood 2009;114:459-468
©2009 by American Society of Hematology
Extracellular matrix mineralization and its heterogeneity near donor eGFP+ and host eGFP−
osteocytes measured by confocal Raman microspectroscopy.
Cristina Panaroni et al. Blood 2009;114:459-468
©2009 by American Society of Hematology
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