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Exam 1 40 What diagnostic test will describe etiology of renal failure? a. ___________ b. ___________ c. FENa d. BUN/crea ratio Answer: C Exam 2 40 Which of the following is true? a. R kidney is higher than L kidney b. Kidneys are fused at upper pole c. L kidney is higher than R kidney d. Pelvic kidney is normal Answer: C 41. Acute cellular rejection is characrerized by a. tubular atrophy b. decoy cells in the urine c. interstitial fibrosis d. nephrotic range proteinuria e. infiltrating leukocytes Answer:B 42. The first dialysis machine was known as the a. kolff rotating drum b. oscillometric memoprint machine c. rontgen vacuum tube d. lippmann capillary electrometer e. damadian indomitable device Answer:A 43. Immunosuppressive medications used for induction therapy include which of the following a. calcineurin inhibitors b. antimetabolites c. intravenous immunogloguline d. rituximab e. anti-thymocyte globulin Answer:B 44. The most common viral infection post transplantation is caused by a. polyoma virus b. herpes simplex c. HIV d. CMV e. adenovirus Answer:B/C/D 45. A 75 yo male with CKD stage V is referred to you for renal replacement therapy. He wishes to ask for your opinion regarding kidney transplantation. Which of the following would be the most appropriate first step? a. consult surgery for dialysis catheter placement b. encourage px to pursue dialysis c. evaluate him for transplantation d. consult the ethics committee e. perform a GFR scan Answer:B. Due to the age of the patient, I believe that kidney transplantation is not appropriate for the patient. Younger 46. Preformed antibodies is determined by a. blood typing c, tissue typing b. tissue x matching d. aota Answer:A 47. Which of the following statements is true? a. (+) crossmatch is an absolute indication to organ transplant b. A zero HLA match is an absolute contraindication to transplantation c. a halo type match means that there is a 50% chance of rejection d. NOTA Answer: D 48. The central components of the immune system necessary for activation of the different immune cascade pathways are the a. antigen presenting cells b. cytokines c. T helper cells d. cytotoxic lymphocytes Answer:A 115. A 55 yo came into your clinic with a sudden spike of blood pressure, causing them to go to the emergency room yesterday. He has a 3 year history of hypertension and was controlled with enalapril 10mg OD, HCTZ 25mg OD. One week ago, his blood pressure reading at the doctor’s office was 140/80 mmHg so his primary care doctor started him on clonidine 75mcg TID. After 3 days , his BP was 110/70 and he started to experience dry mouth, his doctor stopped the clonidine immediately. However yesterday, BP became elevated at 160/90 and he was immediately rushed to the ER. What is the cause of the sudden elevation of BP? a. sudden surge of catecholamines may have caused the HPN b. rebound hypertension from abrupt discontinuation of clonidine c. elevated aldosterone d. high salt diet 118. A 6 yo girl was brought to the ER for edema and decreased urine output. There was note of tea-colored urine and skin lesions on both lower extremities. BP was taken 130/80mmHg. Which is the best anti-hypertensive medication for this patient? a. ACE inhibitor – captopril b. diuretic – furosemide c. beta blocker – progenolol d. vasodilator – hydralazine 119. The ff are common causes of HPN in infants and young children, EXCEPT a. renal vein thrombosis b. ________ of the aorta c. essential HPN d. renal artery stenosis e. bronchopulmonary dysplasia? 120. HPN in the children is defined as ave SBP or DBP 95th percentile for the following a. age, gender and height b. sex, height and weight c. weight, age, height d. age, sex and weight Answer:A. Previous samplex, clearly stated in the trans of Pediatric HPN lecture by Dr.Aragon. 121. BONUS. The renal pathology of this week’s CPC showed findings consistent with a. acute tubular necrosis b. membranous nephropathy c. typhoid GN d. pigment induced nephropathy 122. T/F. If the patient is already on very high dose of furosemide and still has evaded response, it would be wise to add bumetamide. Answer: False 123. T/F. Spironolactone has anti-androgenic properties and is used in the symptomatic treatment of hirsutism.