Download Supplementary Figure 4

UDP-N-acetyl-D-mannosamineN-acetyl-beta-D-
1-(5-Phospho-D-ribosyl)-ATPpyrophosphate
phosphoribosyl-transferase
UDP-N-acetylmuramateNADP+
Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)oxidoreductase
UDP-N-acetyl-D-mannosamine_C17H25N3O17P2
Phosphoribosyl-ATP_C15H21N5O20P4
Undecaprenyl-diphospho-N-acetylmuramoyl--N-acetylglucosamine-L-ala-D-glu-meso-2-6-diaminopimeloyl-D-ala-D-ala_C95H152N8O28P2
Peptidoglycan
D-AlanineD-Alanine
UDP-N-acetylglucosamine_enolpyruvate_C20H26N3O19P2
subunit
ligase
synthesis
(ADP-forming)
Ala-Ala_C6H12N2O3
Tetradecanoyl-[acyl-carrier
protein]malonyl-CoA
Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)(2E)-Tetradecenoyl-[acp]_C25H45N2O8PRS
UDP-N-acetyl-D-glucosamine
Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine_C94H153N8O26P2
UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide)pyrophosphoryl-undecaprenol
2-epimerase
PhosphoenolpyruvateUDP-N-acetyl-D-glucosamine
N-acetylglucosamine
Phosphoribosyl-ATP
pyrophosphohydrolase
meso-2,6-Diaminoheptanedioate
L-Glutamate
carboxy-lyase
UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2-6-diaminopimelate_C35H51N7O26P2
transferase
racemase
LL-2,6-Diaminoheptanedioate
(3R)-3-Hydroxypalmitoyl-[acyl-carrier-protein]
2-epimerase
meso-2,6-Diaminopimelate_C7H14N2O4
D-Glutamate_C5H8NO4
LL-2,6-Diaminopimelate_C7H14N2O4
UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide)pyrophosphoryl-undecaprenol
hydro-lyase
dodecanoyl-[acyl-carrier-protein]malonyl-[acyl-carrier-protein]
N-acetylglucosamine
isopentadecanoyl-lipoteichoic
3-oxotetradecanoyl-acp_C25H45N2O9PRS
isohexadecanoyl-lipoteichoic
transferase
UDP-N-acetyl-D-glucosamine
acid
UDP-N-acetylmuramoyl-L-alanyl-D-glutamatemeso-2,6UDP-N-acetylmuramateL-alanine
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate_C28H39N5O23P2
N6-Acetyl-LL-2,6-diaminoheptanedioate
acidsynthesis
(3R)-3-Hydroxytetradecanoyl-[acyl-carrier-protein]NADP+
2-epimerase
UDP-N-acetylmuramoyl-L-alanine_C23H33N4O20P2
ligase
amidohydrolase
HMA_C25H47N2O9PRS
synthesis
stearoyl-lipoteichoic
(n=24),
palmitoyl-lipoteichoic
UDP-N-acetylmuramoyl-L-alanineD-glutamate
(R)-3-Hydroxytetradecanoly-[acyl-carrier-protein]UDP-N-acetyl(ADP-forming)
(n=24),
acid
UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanyl-_D-alanine_C41H61N9O28P2
linked,
acid
ligase(ADP-forming)
UDP-N-acetylglucosamine_C17H25N3O17P2
linked,
synthesis
N-acetyl-LL-2,6-diaminopimelate_C9H15N2O5
N-acetylglucosamine
synthesis
anteisoheptadecanoyl-lipoteichoic
isotetradecanoyl-lipoteichoic
N-acetylglucosamine
(n=24), substituted
(n=24),
acid
acid
substituted
linked,
linked,
synthesis
anteisopentadecanoyl-lipoteichoic
synthesis
isoheptadecanoyl-lipoteichoic
N-acetylglucosamine
Acetyl-L,L-diaminopimelate
N-acetylglucosamine
myristoyl-lipoteichoic
(n=24),
acid
acid
(n=24),
substituted
aminotransferase
substituted
UDPMurAc(oyl-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala)undecaprenyllinked,
synthesisacidsynthesis
linked,
L-2-Acetamido-6-oxopimelate_C9H11NO6
synthesis
N-acetylglucosamine
(n=24),
UDP-N-acetylglucosamineundecaprenylphosphate
(n=24),
N-acetylglucosamine
Acetyl-CoAL-2,3,4,5-tetrahydrodipicolinate
(n=24),
substituted
linked,
N-acetylglucosamine
substituted
linked,
linked,N2-acetyltransferase
N-acetylglucosamine
-1-phosphate
N-acetylglucosamine
Teichoic
N-acetylglucosamine
substituted
transferase
substituted
acid
substituted
Teichoic (glucose
Undecaprenylphosphate_C55H90O4P
acid substituted)
UDPMurAc(oyl-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala)undecaprenyl(D-alanine export
substituted)
Undecaprenyl-diphosphate
export
phosphohydrolase
Teichoic
acid
(unsubstituted)
export
Poly(glycerol-phosphate)
alpha-glucosyltransferase
Prenol-45n_teichoic
acid_C206H386N2O242P47
D-alanine-poly(phosphoribitol)
ligase
diacylglycerol
1,2-Diacyl-sn-glycerol_dioctadecanoyl_C39H76O5
stearoyl-UDP-glucosyltransferase
kinase
Monoglucosyl-1,2_distearoylglycerol_C45H86O10
(monoglucosyl)
(n-C180)
stearoyl-UDP-glucosyltransferase
(diglucosyl)
Diglucosyl-1,2_distearoylglycerol_C51H96O15
ATPnucleoside-diphosphate
phosphatransferase
ITP_C10H12N4O14P3
IMPNAD+
oxidoreductase
1-(5-phospho-D-ribosyl)-AMP
1,6-hydrolase
phosphoribosylformiminoaicar-phosphate_C15H23N5O15P2
L-HistidinalNAD+
oxidoreductase
L-Histidinal_C6H10N3O
D-erythro-imidazol-glycerol-phosphate_C6H10N2O6P
AICAR_C9H14N4O8P
L-Histidinol_C6H12N3O
L-Histidinol-phosphate
5-Amino-2-oxopentanoate2-oxoglutarate
L-histidinol-phosphate_C6H12N3O4P
phosphohydrolase
aminotransferase
fumarate
reductase
Succinate(acceptor)
succinateoxidoreductase
dehydrogenase
Fumarate_C4H2O4
(irreversible) L-Aspartate
N6-(1,2-Dicarboxyethyl)AMP
ammonia-lyase
AMP-lyase
(S)-Malate
hydro-lyase
12-methyl-3-oxo-tetra-decanoyl-ACP_C26H47N2O9PRS
4-methyl-hexanoyl-ACPmalonyl-[acyl-carrier-protein]
Monoglucosyl-1,2_diisoheptadecanoylglycerol_C43H82O10
C-acyltransferase
(decarboxylating)
isoheptadecanoyl-UDP-glucosyltransferase
isoheptadecanoyl-phosphatidate
(monoglucosyl)
cytidylyltransferase
1,2-Diisoheptadecanoyl-sn-glycerol_C37H72O5
N-(L-Argininosuccinate)
arginie-lyase
15-methyl-trans-hexa-dec-2-enoyl-ACPNAD+
oxidoreductase
(A-specific)
15-methyl-trans-hexa-dec-2-enoyl-ACPNADP+
isoheptadecanoyl-Diacylglycerol
oxidoreductase
15-methyl-trans-hexa-dec-2-enoyl-ACP_C28H51N2O8PRS
15-methyl-hexa-decanoyl-ACP_C28H53N2O8PRS
1,2-diisoheptadecanoyl-sn-glycerol_3-phosphate_C37H72O8P
15-methyl-hexa-decanoyl-ACP[acyl-carrier-protein]
4-methyl-hexanoyl-ACP_C18H33N2O8PRS
kinase
isoheptadecanoyl-1-acylglycerol-3-phosphate
(A-specific)
fa11coa_C38H65N7O17P3S transferase
O-acyltransferase
Monoglucosyl-1,2_dianteisoheptadecanoylglycerol_C43H82O10
12-methyl-3-oxo-tetra-decanoyl-ACPNADP+
oxidoreductase
L-Argininosuccinate_C10H17N4O6
L-CitrullineL-aspartate
ligase
(AMP-forming)
12-methyl-3-hydroxy-tetra-decanoyl-ACP_C26H49N2O9PRS
FACOAL170(ISO)
15-methyl-3-hydroxy-hexa-decanoyl-ACP
hydro-lyase
4-methyl-trans-hex-2-enoyl-ACPNADP+
4-methyl-trans-hex-2-enoyl-ACPNAD+
oxidoreductase
oxidoreductase
(A-specific)
(A-specific)
3-methylbutanoyl-CoA[acyl-carrier-protein]
transferase
isovaleryl-ACP_C16H29N2O8PRS
12-methyl-3-hydroxy-tetra-decanoyl-ACP
hydro-lyase
15-methyl-3-hydroxy-hexa-decanoyl-ACP_C28H53N2O9PRS
3-methylbutanoyl-ACPmalonyl-[acyl-carrier-protein]
C-acyltransferase
(decarboxylating)
5-methyl-3-oxo-hexanoyl-ACP_C18H31N2O9PRS
4-methyl-trans-hex-2-enoyl-ACP_C18H31N2O8PRS
12-methyl-trans-tetra-dec-2-enoyl-ACP_C26H47N2O8PRS
15-methyl-3-oxo-hexa-decanoyl-ACPNADP+
oxidoreductase
5-methyl-3-oxo-hexanoyl-ACPNADP+
oxidoreductase
5-methyl-3-hydroxy-hexanoyl-ACP_C18H33N2O9PRS
12-methyl-trans-tetra-dec-2-enoyl-ACPNADP+
oxidoreductase
12-methyl-trans-tetra-dec-2-enoyl-ACPNAD+
(A-specific)
oxidoreductase
(A-specific)
4-methyl-3-hydroxy-hexanoyl-ACP
15-methyl-3-oxo-hexa-decanoyl-ACP_C28H51N2O9PRS
hydro-lyase
5-methyl-3-hydroxy-hexanoyl-ACP
hydro-lyase
5-methyl-trans-hex-2-enoyl-ACP_C18H31N2O8PRS
anteisopentadecanoyl-phosphatidate
cytidylyltransferase
12-methyl-tetra-decanoyl-ACP_C26H49N2O8PRS
1,2-dianteisopentadecanoyl-sn-glycerol_3-phosphate_C33H64O8P
anteisopentadecanoyl-1-acylglycerol-3-phosphate
fa4coa_C36H61N7O17P3S
12-methyl-tetra-decanoyl-ACP[acyl-carrier-protein]
13-methyl-tetra-decanoyl-ACPmalonyl-[acyl-carrier-protein]
C-acyltransferase
(decarboxylating)
4-methyl-3-hydroxy-hexanoyl-ACP_C18H33N2O9PRS
1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
NCAIR
carboxy-lyase
synthetase
and NCAIR
mutase
5'-Phosphoribosyl-4-carboxy-5-aminoimidazole_C9H13N3O9P
1-(5-Phosphoribosyl)-5-amino-4-carboxyimidazoleL-aspartate
D-erythro-1-(Imidazol-4-yl)glycerol
ligase
3-phosphate
1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
SAICAR_C13H16N4O12P
hydro-lyase
imidazole_acetol-phosphate_C6H8N2O5P
L-HistidinolNAD+
oxidoreductase
10-methyl-dodecanoyl-ACPmalonyl-[acyl-carrier-protein]
C-acyltransferase
(decarboxylating)
6-methyl-3-oxo-octanoyl-ACP_C20H35N2O9PRS
anteisoheptadecanoyl-Diacylglycerol
kinase
synthetase
AIR_C8H14N3O7P
Imidazole-glycerol-3-phosphate
10-Formyltetrahydrofolate5'-phosphoribosyl-5-amino-4synthase
(A-specific)
isoheptadecanoyl-UDP-glucosyltransferase
(diglucosyl)
1,2-Dianteisoheptadecanoyl-sn-glycerol_C37H72O5
ATP4-amino-5-hydroxymethyl-2-methylpyrimidine
5-phosphotransferase
Toxopyrimidine_C6H9N3O
2-(Formamido)-N1-(5-phosphoribosyl)acetamidine
cyclo-ligase
4-amino-5-hydroxymethyl-2-methylpyrimidine
FAICAR_C10H14N4O9P
10-methyl-3-hydroxy-dodecanoyl-ACP
hydro-lyase
10-methyl-trans-dodec-2-enoyl-ACP_C24H43N2O8PRS
10-methyl-3-hydroxy-dodecanoyl-ACP_C24H45N2O9PRS
6-methyl-3-oxo-octanoyl-ACPNADP+
oxidoreductase
anteisoheptadecanoyl-UDP-glucosyltransferase
(monoglucosyl)
ATP4-amino-2-methyl-5-phosphomethylpyrimidine
Thiamin
phosphotransferase
hydrolase 4-Amino-5-phosphomethyl-2-methylpyrimidine_C6H9N3O4P
5'-Phosphoribosylformylglycinamidine_C8H16N3O8P
N-(5'-Phospho-D-ribosylformimino)-5-amino-1NADHguanosine-5'-phosphate
phosphoribosyltransferase
oxidoreductase(deaminating)
Diglucosyl-1,2_dianteisoheptadecanoylglycerol_C49H92O15
anteisoheptadecanoyl-UDP-glucosyltransferase
(diglucosyl)
ATPthiamin
pyrophosphotransferase
5'-PhosphoribosylformylglycinamideL-glutamine
THI_C12H17N4OS
ATP4-methyl-5-(2-hydroxyethyl)-thiazole
amido-ligase
4-Methyl-5--2-phosphoethyl-thiazole_C6H9NO4PS
2-Methyl-4-amino-5-hydroxymethylpyrimidine-diphosphate4-methyl-52-phosphotransferase
4-Amino-2-methyl-5-diphosphomethylpyrimidine_C6H9N3O7P2
Thiamine
transport in
via proton
symport
Inosine
Inosine 5'-monophosphate
5'-triphosphate
phosphohydrolase
pyrophosphohydrolase
IMP_C10H12N4O8P
IMPpyrophosphate
10-methyl-trans-dodec-2-enoyl-ACPNAD+
8-methyl-3-oxo-decanoyl-ACP_C22H39N2O9PRS
oxidoreductase
8-methyl-3-oxo-decanoyl-ACPNADP+
10-methyl-trans-dodec-2-enoyl-ACPNADP+
6-methyl-octanoyl-ACPmalonyl-[acyl-carrier-protein]
10-methyl-3-oxo-dodecanoyl-ACPNADP+
(A-specific)
6-methyl-trans-oct-2-enoyl-ACPNADP+ C-acyltransferase
oxidoreductase
oxidoreductase
8-methyl-3-hydroxy-decanoyl-ACP_C22H41N2O9PRS
6-methyl-octanoyl-ACP_C20H37N2O8PRS
oxidoreductase
oxidoreductase
(A-specific)
(decarboxylating)
(A-specific)
6-methyl-trans-oct-2-enoyl-ACPNAD+
8-methyl-3-hydroxy-decanoyl-ACP
6-methyl-trans-oct-2-enoyl-ACP_C20H35N2O8PRS
6-methyl-3-hydroxy-octanoyl-ACP
10-methyl-3-oxo-dodecanoyl-ACP_C24H43N2O9PRS
oxidoreductase
hydro-lyase 8-methyl-trans-dec-2-enoyl-ACPNADP+
8-methyl-trans-dec-2-enoyl-ACP_C22H39N2O8PRS
10-methyl-dodecanoyl-ACP_C24H45N2O8PRS
oxidoreductase
hydro-lyase
(A-specific)
6-methyl-3-hydroxy-octanoyl-ACP_C20H37N2O9PRS
cyltransferase
(A-specific)
8-methyl-trans-dec-2-enoyl-ACPNAD+
8-methyl-decanoyl-ACP_C22H41N2O8PRS
(decarboxylating)
oxidoreductase
isoheptadecanoyl-lipoteichoic
acid
anteisoheptadecanoyl-lipoteichoic
synthesis
acid
(n=24),
synthesis
linked,
(n=24),
unsubstituted
Diglucosyl-1,2_diisoheptadecanoylglycerol_C49H92O15
linked,
unsubstituted
10-Formyltetrahydrofolate5'-phosphoribosylglycinamide
N-Formyl-GAR_C8H14N2O9P
XMPpyrophosphate
phosphoribosyltransferase
XMP_C10H12N4O9P
Xanthosine
5'-phosphate
phosphohydrolase
IMP
1,2-hydrolase
phosphoribulosylformimino-AICAR-phosphate_C15H23N5O15P2
(decyclizing)
CDP-glycerolpoly(glycerophosphate)
glycerophosphotransferase
stearoyl-lipoteichoic
acid CTPsn-glycerol-3-phosphate
synthesis
cytidylyltransferase
(n=24),
CDPglycerol_C12H19N3O13P2
linked,
unsubstituted
Phosphoribosyl-AMP_C15H21N5O14P2
FACOAL150(anteiso)
12-methyl-tetra-decanoyl-ACPmalonyl-[acyl-carrier-protein]
C-acyltransferase
13-methyl-tetra-decanoyl-ACP_C26H49N2O8PRS
(decarboxylating)
isopentadecanoyl-phosphatidate
13-methyl-tetra-decanoyl-ACP[acyl-carrier-protein]
cytidylyltransferase
transferase 13-methyl-trans-tetra-dec-2-enoyl-ACPNADP+
fa3coa_C36H61N7O17P3S
isopentadecanoyl-1-acylglycerol-3-phosphate
oxidoreductase 14-methyl-3-oxo-hexa-decanoyl-ACP_C28H51N2O9PRS
1,2-diisopentadecanoyl-sn-glycerol_3-phosphate_C33H64O8P
13-methyl-trans-tetra-dec-2-enoyl-ACPNAD+
O-acyltransferase
4-methyl-3-oxo-hexanoyl-ACPNADP+
(A-specific)
oxidoreductase
FACOAL150(ISO)
oxidoreductase
(A-specific)
13-methyl-trans-tetra-dec-2-enoyl-ACP_C26H47N2O8PRS
isopentadecanoyl-Diacylglycerol
anteisoheptadecanoyl-1-acylglycerol-3-phosphate
kinase
14-methyl-3-oxo-hexa-decanoyl-ACPNADP+
O-acyltransferase
oxidoreductase
5-methyl-trans-hex-2-enoyl-ACPNADP+
oxidoreductase
(A-specific)
O-acyltransferase
transferase
anteisopentadecanoyl-Diacylglycerol
kinase
5-methyl-trans-hex-2-enoyl-ACPNAD+
oxidoreductase
(A-specific)
5-methyl-hexanoyl-ACP_C18H33N2O8PRS
1,2-dianteisoheptadecanoyl-sn-glycerol_3-phosphate_C37H72O8P
anteisoheptadecanoyl-phosphatidate
cytidylyltransferase
5-methyl-hexanoyl-ACPmalonyl-[acyl-carrier-protein]
C-acyltransferase
(decarboxylating)
13-methyl-3-hydroxy-tetra-decanoyl-ACP
hydro-lyase
14-methyl-3-hydroxy-hexa-decanoyl-ACP_C28H53N2O9PRS
4-methyl-3-oxo-hexanoyl-ACP_C18H31N2O9PRS
fa12coa_C38H65N7O17P3S
7-methyl-3-oxo-octanoyl-ACP_C20H35N2O9PRS
13-methyl-3-hydroxy-tetra-decanoyl-ACP_C26H49N2O9PRS
FACOAL170(anteiso)
14-methyl-3-hydroxy-hexa-decanoyl-ACP
14-methyl-hexa-decanoyl-ACP[acyl-carrier-protein]
hydro-lyase
transferase
14-methyl-trans-hexa-dec-2-enoyl-ACP_C28H51N2O8PRS
14-methyl-hexa-decanoyl-ACP_C28H53N2O8PRS
14-methyl-trans-hexa-dec-2-enoyl-ACPNADP+
11-methyl-dodecanoyl-ACP_C24H45N2O8PRS
7-methyl-3-oxo-octanoyl-ACPNADP+
11-methyl-trans-dodec-2-enoyl-ACPNADP+
13-methyl-3-oxo-tetra-decanoyl-ACPNADP+
11-methyl-dodecanoyl-ACPmalonyl-[acyl-carrier-protein]
oxidoreductase
13-methyl-3-oxo-tetra-decanoyl-ACP_C26H47N2O9PRS
oxidoreductase
oxidoreductase
C-acyltransferase
(A-specific)
11-methyl-trans-dodec-2-enoyl-ACPNAD+
(decarboxylating)
oxidoreductase
11-methyl-trans-dodec-2-enoyl-ACP_C24H43N2O8PRS
7-methyl-3-hydroxy-octanoyl-ACP_C20H37N2O9PRS
(A-specific)
oxidoreductase
14-methyl-trans-hexa-dec-2-enoyl-ACPNAD+
(A-specific)
4-methyl-3-oxo-hexanoyl-ACPmalonyl-[acyl-carrier-protein]
oxidoreductase
C-acyltransferase
(A-specific)
(decarboxylating)
7-methyl-3-hydroxy-octanoyl-ACP
hydro-lyase
11-methyl-3-hydroxy-dodecanoyl-ACP
hydro-lyase
2-methylbutyryl-ACP_C16H29N2O8PRS
7-methyl-trans-oct-2-enoyl-ACP_C20H35N2O8PRS
11-methyl-3-hydroxy-dodecanoyl-ACP_C24H45N2O9PRS
7-methyl-trans-oct-2-enoyl-ACPNAD+
oxidoreductase
7-methyl-trans-oct-2-enoyl-ACPNADP+
(A-specific)
oxidoreductase
2-methylbutanoyl-CoA[acyl-carrier-protein]
transferase
(A-specific)
7-methyl-octanoyl-ACP_C20H37N2O8PRS
2-Methylbutyryl-CoA_C26H41N7O17P3S
(R)-2,3-Dihydroxy-3-methylpentanoate
hydro-lyase
2,3-Dihydroxy-3-methylvalerate_C6H11O4
(R)-2,3-Dihydroxy-3-methylpentanoateNADP+
oxidoreductase
(R)-3-Hydroxy-3-methyl-2-oxopentanoate_C6H9O4
(S)-2-Aceto-2-hydroxybutanoateNADP+
oxidoreductase
(isomerizing)
2-Aceto-2-hydroxybutanoate_C6H9O4
(S)-2-Aceto-2-hydroxybutanoate
pyruvate-lyase
(carboxylating)
Acetyl-CoAformate
C-acetyltransferase
2-Oxobutyrate_C4H5O3
L-Cystathionine
Lysteine-lyase
O-Acetyl-L-homoserine
(deaminating) L-threonine
succinate-lyase
Cystathionine
ammonia-lyase
(adding
Cystathionine_C7H14N2O4S
L-homocysteine-lyase
cysteine)
(deaminating)
O-Succinyl-L-homoserine
succinate-lyase
L-Serine
(adding
hydro-lyase
cysteine)
(adding
O-Succinyl-L-homoserine
homocysteine)
succinate-lyase
O-Succinyl-L-homoserine_C8H12NO6
(adding
cysteine)
L-HomoserineNAD+
oxidoreductase
L-HomoserineNADP+
oxidoreductase
L-Aspartate-4-semialdehydeNADP+
oxidoreductase
L-Aspartate-4-semialdehyde
(phosphorylating)
4-Phospho-L-aspartate_C4H7NO7P
hydro-lyase
(adding
ATPL-aspartate
pyruvate
4-phosphotransferase
and
Dihydrodipicolinate_C7H5NO4
2,3,4,5-TetrahydrodipicolinateNADP+
oxidoreductase
Shikimate_C7H9O5
PrephenateNADP+
Prephenate_C10H8O6
Dihydroneopterin_C9H13N5O4
L-Aspartate2-oxoglutarate
oxidoreductase(decarboxylating)
aminotransferase
2-Amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8Prephenate
hydro-lyase
(decarboxylating)
11-methyl-3-oxo-dodecanoyl-ACP_C24H43N2O9PRS
9-methyl-decanoyl-ACPmalonyl-[acyl-carrier-protein]
C-acyltransferase
9-methyl-3-oxo-decanoyl-ACP_C22H39N2O9PRS
(decarboxylating)
9-methyl-decanoyl-ACP_C22H41N2O8PRS
9-methyl-trans-dec-2-enoyl-ACPNADP+
oxidoreductase
9-methyl-trans-dec-2-enoyl-ACPNAD+
9-methyl-trans-dec-2-enoyl-ACP_C22H39N2O8PRS
(A-specific)
9-methyl-3-oxo-decanoyl-ACPNADP+
oxidoreductase
oxidoreductase
(A-specific)
fa6coa_C37H63N7O17P3S
FACOAL160(ISO)
rxn07435
14-methyl-pentadecanoyl-ACP[acyl-carrier-protein]
transferase
9-methyl-3-hydroxy-decanoyl-ACP
9-methyl-3-hydroxy-decanoyl-ACP_C22H41N2O9PRS
hydro-lyase
2-Methyl-1-hydroxybutyl-TPP_C17H27N4O8P2S
14-methyl-pentadecanoyl-ACP_C27H51N2O8PRS
rxn07434
14-methyl-trans-pentadec-2-enoyl-ACPNAD+
oxidoreductase
(A-specific)
14-methyl-trans-pentadec-2-enoyl-ACP_C27H49N2O8PRS
O-Succinyl-L-homoserine
succinate-lyase
Succinyl-CoAL-homoserine
(adding
O-succinyltransferase
cysteine)
Acetyl-CoAL-homoserine
O-Phospho-L-homoserine
O-acetyltransferase
O-Phospho-L-homoserine_C4H9NO6P
ATPL-homoserinephospho-lyase
L-Homoserine_C4H9NO3
O-phosphotransferase (adding
water)
L-Aspartate4-semialdehyde_C4H7NO3
7-methyl-octanoyl-ACPmalonyl-[acyl-carrier-protein]
C-acyltransferase
(decarboxylating)
(2S,3S)-3-Hydroxy-2-methylbutanoyl-CoA
hydro-liase
S-(2-Methylbutanoyl)-dihydrolipoamide-E_C13H25NO2S2
isohexadecanoyl-1-acylglycerol-3-phosphate
O-acyltransferase
11-methyl-3-oxo-dodecanoyl-ACPNADP+
oxidoreductase
ShikimateNADP+
5-oxidoreductase
(S)-2-methylbutanoyl-CoAoxygen
2,3-oxidoreductase
(S)-2-methylbutanoyl-CoAenzyme
N6-(dihydrolipoyl)lysine
Tiglyl-CoA_C26H39N7O17P3S
isohexadecanoyl-phosphatidate
1,2-diisohexadecanoyl-sn-glycerol_3-phosphate_C35H68O8P
cytidylyltransferase
isohexadecanoyl-Diacylglycerol
kinase
Formamidopyrimidine
phosphopantothenate-cysteine
N-(5-Phospho-beta-D-ribosyl)anthranilate
(3R)-3-Hydroxybutanoyl-[acyl-carrier-protein]
Acetyl-CoAL-glutamate
2,5-Diaminopyrimidine_nucleoside
(R)-3-Hydroxyoctanoyl-[acyl-carrier_protein]_C19H35N2O9PRS
1-(2-carboxyphenylamino)-1-deoxyribulose_5-phosphate_C12H14NO9P
(2E)-Octenoyl-[acp]_C19H33N2O8PRS
L-Serine
Octanoyl-[acyl-carrier
N-5-phosphoribosyl-anthranilate_C12H14NO9P
N-(5-Phospho-D-ribosyl)anthranilatepyrophosphate
Formamidopyrimidine_nucleoside
(3R)-3-Hydroxyoctanoyl-[acyl-carrier-protein]NADP+
GTP
ATPpantothenate
GTP
nucleoside
ligase
ketol-isomerase
hydro-lyase
triphosphate_C9H15N5O14P3
N-acetyltransferase
hydro-lyase
protein]malonyl-CoA
4-phosphopantothenate_C9H16NO8P
triphosphate_C10H15N5O15P3
1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate
oxidoreductase
7,8-8,9-dihydrolase
4'-phosphotransferase
7,8-8,9-dihydrolase
triphosphate
N-Acetyl-L-glutamate_C7H9NO5
(adding
3-oxooctanoyl-acp_C19H33N2O9PRS
Indoleglycerol_phosphate_C11H13NO6P
(R)-4'-Phosphopantothenoyl-L-cysteine_C12H21N2O9PS
ADC_C10H10NO5
7,8-8,9-dihydrolase
indoleglycerol-phosphate)
2,5-Diamino-6-(5'-triphosphoryl-3',4'-trihydroxy-2'-oxopentyl)-_amino-4-oxopyrimidine_C9H15N5O14P3
(R)-4'-PhosphopantothenateL-cysteine
hexanoyl-[acyl-carrier
ATPN-acetyl-L-glutamate
N-[(R)-4'-Phosphopantothenoyl]-L-cysteine
N2-Acetyl-L-ornithineL-glutamate
ligase
protein]malonyl-[acyl-carrier-protein]
5-phosphotransferase
(1S,2R)-1-C-(indol-3-yl)glycerol
carboxy-lyase
[Acyl-carrier-protein] N-acetyltransferase
3-phosphate
chorismateL-glutamine
4'-pantetheine-phosphohydrolase
indol_C8H7N
Phosphopantetheine_C11H22N2O7PS
aminotransferase 2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)
N-Acetylornithine_C7H14N2O3
L-Serine
hydro-lyase
N2-Acetyl-L-ornithine
(adding
amidohydrolase
hydroxymutase
indoleglycerol-phosphate)
ATPpantetheine-4'-phosphate
N2-Acetyl-L-ornithine2-oxoglutarate
GTP
Chorismate
Phosphoenolpyruvate3-phosphoshikimate
Chorismate_C10H8O6 7,8-Dihydroneopterin_3'-triphosphate_C9H13N5O13P3
adenylyltransferase
aminotransferase
7,8-8,9-dihydrolase
pyruvate-lyase
(amino-accepting)
2-Acetamido-5-oxopentanoate_C7H10NO4
Chorismate
3-phosphoshikimate_C7H9O8P
Dephospho-CoA_C21H33N7O13P2S
N-Acetyl-L-glutamate-5-semialdehydeNADP+
pyruvate-lyase
5-oxidoreductase
2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)
(amino-accepting)Chorismate
ATPshikimate
PrephenateNAD+
pyruvatemutase
ATPdephospho-CoA
3-phosphotransferase
oxidoreductase(decarboxylating)
3'-phosphotransferase
4-amino-4-deoxychorismate
pyruvate-lyase
5-O-(1-Carboxyvinyl)-3-phosphoshikimate
phosphate-lyase
5-O--1-Carboxyvinyl-3-phosphoshikimate_C10H10O10P
Chorismate
6-methyl-trans-hept-2-enoyl-ACPNAD+
oxidoreductase
(A-specific)
6-methyl-trans-hept-2-enoyl-ACP_C19H33N2O8PRS
acetyl-CoA[acyl-carrier-protein]
S-acetyltransferase
Acetyl-ACP_C13H23N2O8PRS
14-methyl-3-hydroxy-pentadecanoyl-ACP
hydro-lyase
14-methyl-3-hydroxy-pentadecanoyl-ACP_C27H51N2O9PRS
14-methyl-3-oxo-pentadecanoyl-ACPNADP+
oxidoreductase
12-methyl-3-oxo-tridecanoyl-ACPNADP+
oxidoreductase
FACOAL140(ISO)
12-methyl-3-hydroxy-tridecanoyl-ACP
hydro-lyase
isotetradecanoyl-1-acylglycerol-3-phosphate
isotetradecanoyl-Diacylglycerol
kinase O-acyltransferase
12-methyl-trans-tridec-2-enoyl-ACP_C25H45N2O8PRS
1,2-diisotetradecanoyl-sn-glycerol_3-phosphate_C31H60O8P
isotetradecanoyl-phosphatidate 12-methyl-trans-tridec-2-enoyl-ACPNAD+
cytidylyltransferase
oxidoreductase
(A-specific)
12-methyl-tridecanoyl-ACP_C25H47N2O8PRS
3-Methyl-2-oxobutanoate_C5H7O3
5,10-Methylenetetrahydrofolate3-methyl-2-oxobutanoate
6-methyl-3-oxo-heptanoyl-ACP_C19H33N2O9PRS
4-methyl-trans-pent-2-enoyl-ACP_C17H29N2O8PRS
Butyryl-[acyl-carrier
protein]malonyl-CoA
alpha-Ribazole_5'-phosphate_C14H18N2O7P
4-methyl-3-hydroxy-pentanoyl-ACP
Butyryl-ACP_C15H27N2O8PRS
hydro-lyase
4-methyl-3-hydroxy-pentanoyl-ACP_C17H31N2O9PRS
butyryl-[acyl-carrier
protein]malonyl-[acyl-carrier-protein]
Nicotinamide
amidohydrolase
Nicotinate-nucleotidedimethylbenzimidazole
2-Dehydropantoate_C6H9O4
4-methyl-3-oxo-pentanoyl-ACPNADP+
3-Oxohexanoyl-[acp]_C17H29N2O9PRS
oxidoreductase
4-methyl-3-oxo-pentanoyl-ACP_C17H29N2O9PRS
6-Phospho-D-gluconateNADP+
2-oxidoreductase
(decarboxylating)
D-Ribulose-5-phosphate
3-epimerase
2-Isopropylmalate D-Ribose-5-phosphate
hydro-lyase
ketol-isomerase
2-Isopropylmaleate_C7H8O4
3,4-Dihydroxy-2-butanone
3-Isopropylmalate
4-phosphate
hydro-lyase synthase
3-4-dihydroxy-2-butanone4-phosphate_C4H8O6P
Nicotinamide
ribonucleotide
N-Ribosylnicotinamide_C11H15N2O5
phosphohydrolase
D-Ribose
N-Ribosylnicotinamideorthophosphate
Adenosineorthophosphate
1,5-phosphomutase
ribosyltransferase
ribosyltransferase
Niacin_C6H4NO2
Nicotinate
Ribose_1-phosphate_C5H10O8P
guanosineorthophosphate
D-ribonucleosideorthophosphate
Nicotinate-nucleotidepyrophosphate
ribosyltransferase
inosineorthophosphate
ribosyltransferase
phosphoribosyltransferase
ribosyltransferase
Xanthosineorthophosphate
Nicotinate
Nicotinate_ribonucleotide_C11H13NO9P
ribosyltransferase
D-ribonucleotidepyrophosphate
Nicotinate
Uridineorthophosphate
phosphoribosyltransferase
D-ribonucleotide
ATPnicotinamide-nucleotide
ribosyltransferase
phosphohydrolase
adenylyltransferase
(3R)-3-Hydroxyhexanoyl-[acyl-carrier-protein]NADP+ 2-methylpropionyl-ACPmalonyl-[acyl-carrier-protein]
oxidoreductase
C-acyltransferase
D-3-Hydroxyhexanoyl-[acp]_C17H31N2O9PRS
isobutyryl-ACP_C15H27N2O8PRS
2-methylpropionyl-CoA[acyl-carrier-protein]
(decarboxylating)
(3R)-3-Hydroxybutanoyl-[acyl-carrier-protein]
transferase
hydro-lyase
D-Glucose-6-phosphateNADP+
1-oxoreductase
Uracil
ion-coupled
Uracil_C4H4N2O2
transport
UMPpyrophosphate
phosphoribosyltransferase
(R)-PantoateNADP+
2-oxidoreductase
Pantoate_C6H11O4
6,7-Dimethyl-8-(1-D-ribityl)lumazine6,7-dimethyl-8-(1-D-ribityl)
4--1-D-Ribitylamino-5-aminouracil_C9H16N4O6
6,7-Dimethyl-8-(1-D-ribityl)lumazine6,7-dimethyl-8-(1-D-ribityl)
(R)-Pantoatebeta-alanine
ligase
(AMP-forming)
beta-Alanine_C3H7NO2
L-Aspartate
1-carboxy-lyase
Lysophospholipase
Hydroxymethylbilane
1-tetradecanoyl-sn-glycerol_3-phosphate_C17H34O7P
L1
hydro-lyase(cyclizing)
1-tetradecanoyl-sn-glycerol
(2-acylglycerophosphotidate,
3-phosphate
Hydroxymethylbilane_C40H38N4O17
O-acyltransferase n-C140)
(periplasm)
(n-C140)
6-Phospho-D-glucono-1,5-lactone
6-phospho-D-glucono-1-5-lactone_C6H10O9P
ATPD-Gluconate
6-phosphotransferaselactonohydrolase
beta-D-Glucose-6-phosphateNADP+
ATPD-glucose
6-Phospho-D-gluconate_C6H11O10P
1-oxoreductase
6-phosphotransferase
beta-D-Glucose_6-phosphate_C6H12O9P
3-Carboxy-3-hydroxy-4-methylpentanoate
3-methyl-2-oxobutanoate-lyase
L-Valine2-oxoglutarate
D-Ribulose5-phosphate_C5H10O8P
2-Isopropylmalate_C7H10O5
aminotransferase
6-methyl-3-oxo-heptanoyl-ACPNADP+
Adenosylcobalamin
oxidoreductase
5'-phosphate
synthase
alpha-Ribazole_C14H18N2O4
4-methyl-pentanoyl-ACPmalonyl-[acyl-carrier-protein]
C-acyltransferase
4-methyl-pentanoyl-ACP_C17H31N2O8PRS
(3R)-3-Hydroxybutanoyl-[acyl-carrier-protein]
(decarboxylating)
hydro-lyase
12-methyl-tridecanoyl-ACP[acyl-carrier-protein]
12-methyl-3-hydroxy-tridecanoyl-ACP_C25H47N2O9PRS
alpha-ribazole
4-methyl-trans-pent-2-enoyl-ACPNAD+
transferase
5-phosphate
oxidoreductase
But-2-enoyl-[acyl-carrier_protein]_C15H25N2O8PRS
phosphatase
(A-specific)
fa1coa_C35H59N7O17P3S
rxn07431
2-Methyl-1-hydroxypropyl-TPP_C16H25N4O8P2S
2-Acetolactate
methylmutase
2-Acetolactate (R)-2,3-Dihydroxy-3-methylbutanoateNADP+
ALCTT_C5H7O4
oxidoreductase
pyruvate-lyase
2,3-Dihydroxy-3-methylbutanoateNADP+
(carboxylating)
oxidoreductase
rxn07430
2,3-Dihydroxy-isovalerate_C5H9O4
2-Acetolactate
(isomerizing)
carboxy-lyase
2,3-Dihydroxy-3-methylbutanoate
hydro-lyase
rxn04413
6-methyl-3-hydroxy-heptanoyl-ACP
hydro-lyase
Acetoacetyl-ACP_C15H25N2O9PRS
10-methyl-undecanoyl-ACPmalonyl-[acyl-carrier-protein]
14-methyl-3-oxo-pentadecanoyl-ACP_C27H49N2O9PRS
C-acyltransferase
(3R)-3-Hydroxybutanoyl-[acyl-carrier
(decarboxylating)
protein]NADP+
12-methyl-3-oxo-tridecanoyl-ACP_C25H45N2O9PRS
oxidoreductase
12-methyl-tridecanoyl-ACPmalonyl-[acyl-carrier-protein]
C-acyltransferase
(decarboxylating)
(R)-3-Hydroxybutanoyl-[acyl-carrier_protein]_C15H27N2O9PRS
ATPcobinamide
Cobeta-adenosyltransferase
Adenosyl_cobinamide_C58H85CoN16O11
Adenosyl
cobinamide
Adenosyl_cobinamide
kinase
phosphate_C58H84CoN16O14P
Adenosyl
cobinamide
phosphate
6-methyl-3-hydroxy-heptanoyl-ACP_C19H35N2O9PRS
Adenosylcobinamide-GDP_C68H96CoN21O21P2
guanyltransferase
Acyl-[acyl-carrier-protein]malonyl-[acyl-carrier-protein]
myristoyl-1-acylglycerol-3-phosphate
O-acyltransferase
Arbutin
6-phosphate
Salicin
glucohydrolase
6-phosphate
tetradecanoyl-ACP[acyl-carrier-protein]
transferase
Myristoyl-CoA_C35H59N7O17P3S
Salicin-6P_C13H18O10P
glucohydrolase
Salicin
6-phosphate
glucohydrolase
acyl-CoA
dehydrogenase
(tetradecanoyl-CoA)
myristoyl-CoAacetylCoA
(2E)-Tetradecenoyl-CoA_C35H57N7O17P3S
C-myristoyltransferase
(S)-3-Hydroxytetradecanoyl-CoA
hydro-lyase
5-Aminolevulinate
hydro-lyase(adding
5-aminolevulinate
and
5-Aminolevulinate_C5H9NO3
3-Oxopalmitoyl-CoA_C37H61N7O18P3S
(S)-3-Hydroxytetradecanoyl-CoA_C35H59N7O18P3S
(S)-3-Hydroxytetradecanoyl-CoANAD+
oxidoreductase
3-Oxotetradecanoyl-CoA_C35H57N7O18P3S
Lauroyl-CoAacetyl-CoA
C-acyltransferase
1-hydroxy-2-methyl-2-(E)-butenyl
4-diphosphate
reductase
dimethyallyl
1-Hydroxy-2-methyl-2-butenyl_4-diphosphate_C5H10O8P2
(dmpp)
diphosphateNADP+
DMAPP_C5H10O7P2
oxidoreductase
Porphobilinogen
1-hydroxy-2-methyl-2-(E)-butenyl
isopentenyl-diphosphateNAD(P)+
Isopentenyl-diphosphate
ammonia-lyase
4-diphosphate
oxidoreductase
Dimethylallyl-diphosphateisopentenyl-diphosphate
delta3-delta2-isomerase
(polymerizing)
reductase
Geranyl-diphosphateisopentenyl-diphosphate
trans,trans-Farnesyl-diphosphateisopentenyl-diphosphate
(ipdp)
geranyltrans-transferase
GGTT
Porphobilinogen_C10H13N2O4
di-trans,poly-cis-Decaprenyl-diphosphateisopentenyl-diphosphate
Isopentenyldiphosphate_C5H10O7P2
trans-hexaprenyltranstransferase
PPTT
ATP(R)-5-diphosphomevalonate
Farnesyl
carboxy-lyase
diphosphateIsopentenyl
(dehydrating)
diphosphate
farnesyl
rxn12008
transferase
(S)-4-Amino-5-oxopentanoate
Farnesylfarnesylgeraniol_C40H66O7P2
4,5-aminomutase
(S)-3-Hydroxyhexadecanoyl-CoANAD+
oxidoreductase
1,4-dihydroxy-2-naphthoate
L-Glutamate1-semialdehyde_C5H9NO3
octaprenyltransferase
(S)-3-Hydroxyhexadecanoyl-CoA_C37H63N7O18P3S
(S)-3-Hydroxyhexadecanoyl-CoA
hydro-lyase
L-glutamate-semialdehyde
NADP+