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A novel calcium-binding site of von Willebrand factor A2
domain regulates its cleavage by ADAMTS13
by Minyun Zhou, Xianchi Dong, Carsten Baldauf, Hua Chen, Yanfeng Zhou, Timothy
A. Springer, Xinping Luo, Chen Zhong, Frauke Gräter, and Jianping Ding
Blood
Volume 117(17):4623-4631
April 28, 2011
©2011 by American Society of Hematology
Structure of ssA2.
Minyun Zhou et al. Blood 2011;117:4623-4631
©2011 by American Society of Hematology
Force-probe MD simulations of a wtA2 model with or without a Ca2+ bound at the metal-binding
site.
Minyun Zhou et al. Blood 2011;117:4623-4631
©2011 by American Society of Hematology
Effect of Ca2+ binding on A2 cleavage by ADAMTS13.
Minyun Zhou et al. Blood 2011;117:4623-4631
©2011 by American Society of Hematology
Effect of mutations at the Ca2+-binding site on A2 cleavage by ADAMTS13.
Minyun Zhou et al. Blood 2011;117:4623-4631
©2011 by American Society of Hematology
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