Download 3764-3771 December 1, 1999

Altered Development and Cytokine Responses of Myeloid
Progenitors in the Absence of Transcription Factor,
Interferon Consensus Sequence Binding Protein
by Marina Scheller, John Foerster, Clare M. Heyworth, Jeffrey F. Waring, Jürgen
Löhler, Gary L. Gilmore, Richard K. Shadduck, T. Mike Dexter, and Ivan Horak
Blood
Volume 94(11):3764-3771
December 1, 1999
©1999 by American Society of Hematology
Increased number of myeloid progenitor cells generated in ICSBP−/− mice in response to IL-3
and GM-CSF in vitro.
Marina Scheller et al. Blood 1999;94:3764-3771
©1999 by American Society of Hematology
Dose-response curves of colony formation in the presence of cytokines in vitro.
Marina Scheller et al. Blood 1999;94:3764-3771
©1999 by American Society of Hematology
Reduced response of hematopoietic progenitor cells from ICSBP−/− mice to M-CSF.
Marina Scheller et al. Blood 1999;94:3764-3771
©1999 by American Society of Hematology
Long-term reconstitution of lethally irradiated mice.
Marina Scheller et al. Blood 1999;94:3764-3771
©1999 by American Society of Hematology
Hematopoietic progenitors from ICSBP−/−mice display reduced adhesion to fibronectin, but not
to laminin. c-kit+–enriched cell fractions were prepared as described in Materials and Methods.
Marina Scheller et al. Blood 1999;94:3764-3771
©1999 by American Society of Hematology
Expression of
4,
5, and β1-integrins on ICSBP-deficient progenitor cells.
Marina Scheller et al. Blood 1999;94:3764-3771
©1999 by American Society of Hematology