Download Supplementary Table S6

NaBu-induced Gene Expression and Associated Epigenetic changes in HSV-1 Reactivation
TABLE S6 Sodium butyrate induced 17Syn+ upregulation of hormone activity and
signaling genes (12/56; 21%)
Gene nameNetAffx
designation
Gene symbol
(description)
Gene function
Fold change:
Microarray
(qPCR)
(Genbank
accession
number)
1455913_x_at
Ttr (transthyretin)
hormone activity;
choroid plexus
+16.2 (+16.1)
Ttr 1 (transthyretin
homolog 1)
hormone activity;
choroid plexus
+15.6 (ND)*
Ttr 2 (transthyretin
homolog 2)
hormone activity;
choroid plexus
+12.0 (ND)
Ttr 3 (transthyretin
homolog 3)
hormone activity;
choroid plexus
+ 9.7 (ND)
Tshb (thyroid stimulating
hormone, beta subunit)
hormone activity;
thyroid hormone
+2.6 (ND)
Cga (glycoprotein
hormones, alpha subunit)
hormone activity;
pituitary hormone
+2.8 (+3.7)
Pomc1 (proopiomelanocortin-alpha )
hormone activity;
neuropeptide
signaling pathway
+10.8 (+12.7)
Pomc1 homolog (proopiomelanocortin-alpha
homolog)
hormone activity;
neuropeptide
signaling pathway
+7.7 (ND)
Stoml3 [stomatin
(Epb7.2)-like 3]
signal transducer
activity; protein
binding
(AV152953)
1459737_s_at
(AA408768)
1454608_x_at
(BG141874)
1451580_a_at
(BC024702.1)
1450371_at
(NM_009432.1)
1418549_at
(NM_009889.1)
1455858_x_at
(BB020616)
1433800_a_at
(AV173741)
1447847_x_at
(BB172310)
+11.1 (ND)
NaBu-induced Gene Expression and Associated Epigenetic changes in HSV-1 Reactivation
1441036_at
(BB189586)
1422200_at
(BI409406)
1422199_at
(NM_011010.1)
Stoml3 homolog
[stomatin (Epb7.2)-like 3
homolog]
signal transducer
activity; protein
binding
+10.7 (ND)
Omp (olfactory marker
protein)
signal transducer
activity; protein
binding
+4.8 (ND)
Omp homolog (olfactory
marker protein homolog)
signal transducer
activity; protein
binding
+4.6 (ND)
Hormone/signaling activity gene expression in the 17Syn+ latent TG relative to its
mutant, LAT negative recombinant, 17Pst(LAT-) latent TG 1 hour post NaBu i.p. of
mice based on microarrays and 3 genes on qPCR. Results are expressed as an
expression ratio of the latent 17Syn+ latent TG to the 17Pst(LAT-) latent TG of NaBu
treatment, normalized against β-actin expression levels using the 2-CT method (Livak
and Schmittgen, 2001).