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Dr. AASHISH H. PANCHAL (M.Pharm., Ph.D.) TRISHA INSTITUTE OF BIOLOGY GSEB/CBSE/ISC/NEET COMPLETE BIOLOGY SOLUTION STD-12 (Semester-4) Sub: Biology (056) (E) CHAPTER-9 Molecular Basis of Inheritance Time: 15 Min. PART-A Marks:40 Note: (1) In this section total 50 questions, each carry 1 mark (2) All questions are compulsory 1. The unwinding of DNA helix is carried out by the enzyme (a) DNA ligase (b) DNA helicase (c) DNA polymerase (d) topoisomerase 2. (a) 3. (a) Anticodon is present on rRNA (b) tRNA (c) DNA (d) mRNA Amino acid sequence in protein synthesis is decided by the sequence of tRNA (b) mRNA (c) cDNA (d) rRNA 4. (a) RNA code for DNA codon ATG will be ATG (b) AUG (c) UAC (d) UAA 5. During protein synthesis in an organism, at one point the process comes to a halt. Select the group of the three codons from the following, from which any one of the three could bring about this halt? (a) UUU, UCC, UAU (b) UUC.UUA, UAC (c) UAG, UGA, UAA (d) UUG, UCA, UCG 6. Ligase is an enzyme responsible for (a) Renaturation of DNA (b) proof reading (c) joining of DNA bits (d) breaking of DNA 7. Central dogma of modern biology is (a) DNA —> RNA -> Proteins (b) RNA -> DNA -> Proteins (c) Protein --> DNA -->RNA (d) RNA -> Proteins -> DNA 8. A gene of operon, which synthesizes a repressor protein is (a) promotor gene (b) structural gene (c) operator gene (d) regulator gene 9. In E. coli, lac operon is induced by (a) p-galactosidase (b) lactose (c) T gene (d) promotor gene 10. Which enzyme is responsible for linking the fragments of DNA (a) DNA polymerase III (b) Endonuclease (c) DNA polymerase I (d) DNA ligase 11. Which one of the following ratio is constant in DNAs of different species (a) A + T / C + G (b) A+G/T+C (c) A+C/U+G (d) A+U/C+G 12. The one which is capable of self replication is (a) DNA (b) RNA (c) Enzyme (d) Protein 13. Okazaki fragments are synthesised on (a) Leading strands of DNA only (b) Lagging strands of DNA only (c) Both leading and lagging strands of DNA (d) Complementary DNA 14. Which one of the following pairs is correctly matched with regard to the codon and the amino acid coded by it (a) UUA-Valine (b) AAA-Lysine (c) AUG-Cysteine (d) CCC-Alanine 15. A polypeptide of five amino acids is synthesized during protein synthesis in eukaryotic cells. Which one of the following can be the correct polypeptide (a) Glycine — valine — methionine — histidine — lysine (b) Methionine — glycine — histidine — lysine — valine (c) Valine — methionine — glycine — histidine — lysine(d) Histidine — lysine — methionine — valine — glycine ___________________________________________________________________________________________________________________________________________ Time: 45min. PART-B SECTION-A Note: Do as directed: Answer the question each question carry 2 Marks 1) 2) 3) 4) Marks:14 08 Application of DNA fingerprint. why DNA is a genetic material and RNA is not. explain the Chargaff rule Give the salient feature of HGP SECTION-B Note: Do as directed: Answer the question each question carry 3 Marks 1. Write a note on transcription 2. Explain the Griffith experiment. 3. Explain the lac operon with figure SECTION-C Note: Do as directed: Answer the question each question carry 4 Marks 4. Explain the translation with figure 5. regulation of gene expression. M.No. : 09898715582, E-mail: [email protected] 09 08 Page 1 of 2 Dr. AASHISH H. PANCHAL (M.Pharm., Ph.D.) TRISHA INSTITUTE OF BIOLOGY 1 B 11 B M.No. : 09898715582 2 B 12 A 3 B 13 B ANSWER KEY 4 5 6 7 C C C A 14 15 16 17 B B 8 D 18 E-mail: [email protected] 9 B 19 GSEB/CBSE/ISC/NEET COMPLETE BIOLOGY SOLUTION 10 D 20 Page 2 of 2