Download Supplementary Table S4

Table S4, related to Table 1.
KIF1B mutation reports in neuroblastoma tumors K14 and K10
K14 and K10 mutation reports is based on custom target sequencing of human
chromosome 1 from 10,270,764 to 10,441,661 using HiSeq2000 PE100 with minimum 80x
coverage. Highlighted row indicates a homozygous SNP (RefSNP rs77172218)
corresponding to chromosome 1 position 10,428,570 and heterozygous SNP RefSNP
rs41274458 (K14) corresponds to chromosome 1 position 10,363,664. RefSNP rs77172218
corresponds to a missense mutation from G to A at gene position 4912, resulting in an
amino acid mutation at position 1554 from valine (V) to methionine (M). RefSNP
rs41274458 (K10) corresponds to a missense mutation from G to T at gene position 2673,
resulting in an amino acid mutation at position 807 from methionine (M) to isoleucine (I).
RefSNP rs41274458 occurs within KIF1Bβ intron.
MUTATION REPORT K10:
#var_index,chrom,left,right,ref_seq,var_type,zygosity,var_seq1,var_seq2,var_score,not_ref_score,coverage,read_count1,read_count2,
conservation,gene_name,transcript_name,where_in_transcript,change_type1,ref_peptide1,var_peptide1,change_type2,ref_peptide2,
var_peptide2,dbsnp,dbsnp_build
519,chr1,10363664,10363665,g,SNP,Het,t,g,35.00000000,35.00000000,235,113,120,,KIF1B,NM_015074,Intron,,,,,,,rs41274458,127
519,chr1,10363664,10363665,g,SNP,Het,t,g,35.00000000,35.00000000,235,113,120,,KIF1B,NM_183416,CDS,Non-Synonymous,M,I,,,,rs41274458,127
K10 COVERAGE:
#chromosome,start,end,num_bases,num_covered_bases,mean_coverage,gene
chr1,10270765,10441661,170897,170857,177.6,KIF1B
MUTATION REPORT K14:
390,chr1,10428570,10428571,g,SNP,Hom,a,a,35.00000000,35.00000000,376,351,351,,KIF1B,NM_015074,CDS,Non-Synonymous,V,M,NonSynonymous,V,M,rs77172218,131
K14 COVERAGE:
#chromosome,start,end,num_bases,num_covered_bases,mean_coverage,gene
chr1,10270765,10441661,170897,170855,226.8,KIF1B
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