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Dominant role of CD47–thrombospondin-1 interactions in
myeloma-induced fusion of human dendritic cells:
implications for bone disease
by Anjli Kukreja, Soroosh Radfar, Ben-Hua Sun, Karl Insogna, and Madhav V.
Dhodapkar
Blood
Volume 114(16):3413-3421
October 15, 2009
©2009 by American Society of Hematology
Myeloma promotes MGC formation by inducing cell fusion in human dendritic cells.
Anjli Kukreja et al. Blood 2009;114:3413-3421
©2009 by American Society of Hematology
Characterization of MGCs present in myeloma-DC cocultures.
Anjli Kukreja et al. Blood 2009;114:3413-3421
©2009 by American Society of Hematology
Mechanism of myeloma-mediated MGC formation.
Anjli Kukreja et al. Blood 2009;114:3413-3421
©2009 by American Society of Hematology
Mechanism of myeloma-mediated cell fusion of DCs to OCLs. (A) Myeloma cells (U266) and DCs
were cocultured overnight at a tumor/DC ratio of 1:2.
Anjli Kukreja et al. Blood 2009;114:3413-3421
©2009 by American Society of Hematology
Role of RANK-RANKL pathway.
Anjli Kukreja et al. Blood 2009;114:3413-3421
©2009 by American Society of Hematology
Effect of TSP-1 blockade on PTH-induced hypercalcemia in vivo.
Anjli Kukreja et al. Blood 2009;114:3413-3421
©2009 by American Society of Hematology
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