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Arrival of action potential Neurotransmitter Receptor Ca+ Post synaptic membrane Calcium ions cause synaptic vesicles to fuse with presynaptic membrane New action potential Exocytosis Na+ (Cation) channel Synaptic Vesicle Presynaptic membrane Membrane depolarises causing calcium ion channel to open Neurotransmitter e.g. Acetylcholine Synaptic cleft Voltage gated Ca+ channel Na + Neurotransmitters diffuse across the synaptic Cleft Na+ ions diffuse in Synaptic Transmission Neurotransmitters are reabsorbed by presynapse or are broken down by enzymes Ca+ ions diffuse in