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SfRBMUAB2017RegionalRedoxSymposium,Abstract/PosterNumbers Poster# FULLNAME LAST TITLE InhibitionofPlasmaparaoxonase1activitybyIsolevuglandinsanditsadducts 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 GeetikaAggarwal IsrarAhmad KhandakerAhmed MabrukaAlfaidi SandeepKumarBarodia GloriaABenavides KarenBernard NathanielBone AshleyBurg BaluKChacko RubenDagda KatelynDunigan ElizabethEntwistle BrandonM.Fox KahYongGoh LinlinGu MichelleJohnson Aggarwal Ahmad Ahmed Alfaidi Barodia Benavides Bernard Bone Burg Chacko Dagda Dunigan Entwistle Fox Goh Gu Johnson 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 MurugaesonKumar JamesA.Lambert JenniferLarson-Casey MorganLocy RuthE.McDowell TaneciaMitchell DouglasMoellering IjeomaObi Joo-YeunOh XiaosenOuyang ParamitaPati JustinQuiles RajeshKumarRadhakrishnan KellieRegal KarinaRicart RachelRock VikramSaini Kumar Lambert BromineInhalationInPregnantMiceInducesSystemicandPulmonaryHypertension,FetalGrowthRestriction,HeartFailure,andDeath Larson-Casey CigarettesmokeimpairsalveolarmacrophagehostdefenseviaRac2inhibition FibronectinisModifiedbyo,o’-DityrosineCross-linking:ImplicationsforIdiopathicPulmonaryFibrosis Locy McDowell TargetingCD4TcellmetabolisminType1diabetes Mitchell Dietaryoxalatealtersmonocytemitochondrialfunctioninhealthysubjects Moellering UABDiabetesResearchCenterBio-AnalyticalREDOXBiology[BARB]Core EarlyLifeStress(ELS)inducesArginase1GeneExpressionintheRenalCortexofAdultMaleRatsUnderHighSaltDiet Obi Oh Peroxiredoxin-2recyclingisinhibitedinsicklecelldiseaseonmiceandhuman Ouyang Anessentialroleofnuclearreceptorbindingfactor-2(NRBF-2)inlearningandmemory Pati HDAC1,NOS3,andcircadianclockgeneexpressionintheendothelium Quiles DifferentialRegulationofmiRNAandmRNAExpressionintheMyocardiumofNrf2KnockoutMice RadhakrishnanAblationofAntioxidantTranscriptionFactorNrf2InducesAtrialRemodelingAfterChronicResistanceExercise Regal RegulationofendothelialN-glycansduringatherosclerosis:aroleforhydrogenperoxide Ricart Chlorinatedlipids,formedafterchlorinegasexposure,havedifferenttoxicityinendothelialandepithelialcells ExtracellularCatalaseProductioninVibrio species Rock Saini Host-generatedHydrogensulfidesupportsMycobacteriumtuberculosisrespirationandgrowthtoaggravateTBdisease HemeScavengingPreventsBr2InhalationInjury-InducedPeribronchialFibrosis Inhibitionoforalnitratereductaseactivity:anewmechanismforacutelunginjury. MODULATIONOFMYOCARDIALISCHAEMICINJURYBYCARBONMONOXIDERELEASINGMOLECULE-A1INAPORCINEMODELOFACUTE REPERFUSIONINFARCTION RoleofParkinandPINK1inMitochondrialHealthandAge-relatedNeurodegeneration IntegratedMeasuresofCellularBioenergeticsandMitochondrialfunctioninhumanPlateletsintheDiagnosisofMetabolicDisease Glutaminolysisinfibroblastactivationandpulmonaryfibrosis AMPK-dependentActivationofAutophagyOvercomesParkinDeficiencyandDiminishesSeverityofEndotoxin-inducedAcuteLungInjury NOX-derivedsuperoxidedrivesmacrophageanti-viralresponsesduringCB3infectiontotriggerType1diabetes Bioenergeticandmetabolomicanalysisofplateletsamplesforprecisionmedicine PINK1RegulatesBrainDerivedNeurotrophicFactorSignalingtoStimulateDendriteOutgrowthandMitochondrialFunction ThioredoxinReductaseInhibitorsInducesPulmonaryHemeOxygenase-1ByNrf2-independentMechanisms EnvironmentalchangereducesabundanceandchangescompositionofexpressedfungalclassIIperoxidasesinsoil HumanizedSickleCellDiseaseMiceExhibitaBluntedPressorResponsetoAcuteBehavioralStress EffectofMitoquinoneTreatmentonCardiacFunctionandPathophysiologyinPressureOverload-inducedHeartFailure TheMitochondrialCalciumUniporterModulatesMacrophageMetabolicReprogramminginPulmonaryFibrosisDevelopment UsingCu(I)-catalyzedAzide–AlkyneClickChemistryasatooltomeasurethe4-HNEproteomeinhumanneutrophils Reactiveoxoacidsofsulfurspecies(ROSS):Sulfenic,sulfoxylic,thiosulfuorusandthiosulfinicacidschemicalcharacterizations. FriendorFoeintherealmofsulfurchemicalbiology? 35 36 37 38 39 40 41 42 43 RandeeS.Sedaka GobinathShanmugam MatthewRyanSmith BrianSpurlock JenniferValcin WillayatYousufWani Liang-JunYan LindaZhang RachaelTindell Sedaka Shanmugam Smith Spurlock Valcin Wani Yan Zhang Tindell Flow-MediatedHistoneDeacetylase1Export:NovelActivatorofCollectingDuctNitricOxideProduction ModerateExerciseTrainingAttenuatesIsoproterenol-InducedMyocardialDamagebyActivatingNrf2-Signaling IdentificationofhumanlungepithelialmetabolicresponsestoacutePAHexposure ThenovelRT-SQuARED-Mmethodrevealsthedirectrelationshipbetweenmitochondrialdynamicsandredoxpotential ChronicAlcoholConsumptionAltersDiurnalRhythmsinTriglycerideandFattyAcidMetabolismGenesinMice:RoleoftheMolecularCircadianClock RoleofO-GlcNAcylationinAutophagyandα-SynucleinHomeostasis Redoximbalanceandmitochondrialabnormalitiesinthediabeticlung Isolevuglandin,ahighlyreactivelipiddicarbonyl,causesdeleteriousconsequencestohigh-densitylipoproteinstructureandfunction SeleniumSupplementationEnhancesNuclearFactorE2-relatedfactor-2(Nrf2)InductionbytheThioredoxinReductaseInhibitorAuranofin