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Robert T. Wheeler
Whitehead Institute for Biomedical Research
9 Cambridge Center
Cambridge, MA 02142
(617) 258-5232 (phone)
(617) 258-9872 (fax)
E-mail: [email protected]
Education and Professional Experience:
2000-present
Whitehead Institute
Cambridge, MA
Post-doctoral Fellow
Sponsor: Gerald R. Fink, PhD
1994-2000
Stanford University
Stanford, CA
PhD, Department of Developmental Biology
Advisor: Lucy Shapiro, PhD
Thesis Title: “Dynamic Localization of Bacterial Signaling Proteins Controlling
Differentiation and Cell Cycle Progression”
1993-1994
University of Munich
Munich, Germany
Research Assistant
Advisor: Diethard Tautz, PhD
1989-1993
Harvard College
Cambridge, MA
B. A. Biology, Magna Cum Laude
Honors Thesis Advisor: Daniel G. Jay, PhD
Honors, Fellowships, and Grants:
2006-present
2004-2006
2005
2001-2004
1994-1997
1993-1994
1991, 1992
Merck Inc. Investigator Initiated Studies Program Grant
Charles A. King Trust Fellowship
Keystone Symposium Travel Grant (NIH/NIAID) “Innate
Immunity to Pathogens”
Burroughs Wellcome Fund Fellowship of the Life Sciences
Research Foundation
National Science Foundation Pre-doctoral Fellowship
Fulbright Fellowship
Ford Undergraduate Research Grants
Professional Experience:
Invited Speaker:
Thomas Jefferson University, Dept. Microbiology and Immunology, April 2007
Stanford University, Dept. Biological Sciences, March 2007
Northeastern University, Dept. Biology, February 2007
Seminar, Dept. Molecular and Cell Biology, Boston University Goldman School of
Dentistry, 2002
Platform Presentations:
Candida and Candidiasis, March 2006
Keystone Symposium “Innate Immunity to Pathogens,” February 2005
International Workshop for Integrated Yeast Sciences, 2004
NE Regional Yeast Meeting, 2003
Poster Presentations:
Keystone Symposium, “Linking Innate with Adaptive Immune Responses,” 2003
Candida and Candidiasis, 2004
Yeast Genetics and Molecular Biology Meeting, 2002
Cold Spring Harbor Symposium “Microbial Pathogenesis & Host Response,” 2005
Peer Reviewer: Molecular Microbiology, Archives of Medical Research, European Cytokine
Network
Service and Mentoring:
Whitehead Teacher Partner Program, invited seminar on Fungal Pathogenesis (2006)
Whitehead Board of Associates, invited presentation (2003)
Whitehead Post-doctoral Advisory Group, served (2001-2003)
Whitehead Library Advisory Group, served (2005)
MIT/Whitehead Post-doctoral Career Seminars, organized (2002-2003)
Whitehead High School Student Program, tour guide (2005-2006)
Direct supervisor of technical associate, Diana Kombe (9/2006-present)
Closely supervised PhD student, Joel Moxley (3/2004-1/2007)
Closely supervised an undergraduate, Rishi Puram (1/2005-5/2005)
Supervised several rotation students (both Fink Lab and Shapiro Lab)
Publications:
Johnnidis J.B., Harris M.H., Wheeler R.T., Stehling-Sun S., Lam M.H., Kirak O.,
Brummelkamp T.R., Fleming M.D. and Camargo F.D. (2008) Regulation of progenitor cell
proliferation and granulocyte function by microRNA-223. Nature (in press).
Wheeler R.T., Fink G.R. (2006) A drug-sensitive genetic network masks fungi from the immune
system. PLoS Pathog. Apr;2(4):e35. Epub 2006 Apr 28.
Wheeler, R. T., Kupiec, M., Magnelli, P., Abeijon, C. and Fink, G.R. (2003) A Saccharomyces
cerevisiae mutant with increased virulence. Proc Natl Acad Sci U S A. 100(5):2766-70.
Wheeler, R. T. and Shapiro, L. (1999) Differential localization of two histidine kinases
controlling bacterial cell differentiation. Molecular Cell 4, 683-694
Wheeler, R. T., Gober, J. W. and Shapiro, L. (1998) Protein localization during the Caulobacter
crescentus cell cycle. Curr. Opin. Microbiol. 6, 636-642.
Wheeler, R. T. and Shapiro, L. (1997) Bacterial Chromosome Segregation: Is There a Mitotic
Apparatus? Cell 88, 577-579.
Winzeler, E., Wheeler, R. and Shapiro, L. (1997) Transcriptional analysis of the Caulobacter
4.5S RNA ffs gene and the physiological basis of an ffs mutant with a Ts phenotype. J. Mol.
Biol. 272(5), 665-676.