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Gene Density in Different Organisms Species Genome Size Approx. # of genes Gene density (genes/Mb) Escherichia coli 4.6 4,400 950 Agrobacterium tumifaciens 5.7 5,400 960 12 5,800 480 Arabidopsis thaliana 125 25,500 200 Drosophila melanogaster 180 13,700 80 Homo sapiens 2,900 27,000 9.3 PROKAYOTES: EUKARYOTES: Sacharomyces cerevisiae Structural organization of the genome The nucleosome 1 The 30-nm Fiber Chromosome Scaffold Heterochromatin and Euchromatin 2 Gene Expression DNA RNA Protein Replication Transcription Translation Phenotype *Gene *Gene expression Genes control inherited variation via: DNA, RNA and protein *Protein coding gene Phenotype Brief overview of transcription: 3