Download Harish Changotra, Ph.D.

[email protected]; [email protected]
Harish Changotra, Ph.D.
Professional Experience
07/2015 – Present
Associate Professor, Department of Biotechnology and Bioinformatics, JUIT, Waknaghat,
India
07/ 2011 – 06/2015
Assistant Professor, Department of Biotechnology and Bioinformatics, JUIT, Waknaghat,
India
02/ 2006 – 12/2010
Post Doctoral Scientist, Department of Microbiology and Immunology, Louisiana State
University Health Sciences Center (LSUHSC-S), Shreveport, Louisiana, US
07/ 2005 – 02/ 2006
Post Doctoral Fellow, Molecular Genetics Division, JL Pettis Memorial VA
Medical Center, Loma Linda, California, US
09/ 2004 – 07/ 2005
Post Doctoral Fellow, Molecular Genetics Lab., National Institute of Immunology, New
Delhi, India
Teaching
Immunology, Vaccines, Infectious Diseases, Vaccine Production, Molecular Genetics and Genetic Counseling courses to B
Tech and M Tech students.
Current Research Interests
Biology of viral diseases: Virus-host interactions, autophagy mechanisms in viral infections, genetic susceptibility of HBV
infection, viral diarrhea.
Grants
 Rapid Grant for Young Investigators (2011-12; PI) by Department of Biotechnology (DBT), Government of India.
 DST-Fast Track (2013; PI) by Department of Science and Technology (DST), Government of India.
 Ad-hoc project (2013; Co-PI) by Indian Council of Medical Research (ICMR), Government of India.
 Awarded by ICMR (2016; Co-PI) “Title: Role of plasma level of soluble receptor for advanced glycation end-products
(sRAGE) in COPD patients-a hospital-based case control study”.
Research Guidance
Ph.D. – 01 awarded, 04 (currently enrolled); B. Tech (biotechnology) – 07 completed, 04 currently enrolled; M. Tech
(Biotechnology) – 07 completed.
Department of Biotechnology and Bioinformatics, JUIT, Waknaghat 173 234, H.P., India
Tel. +91 988 233 7662
1. Swapnil Jain; Ph.D. thesis awarded by JUIT, Solan. Title: ‘Molecular characterization of group a rotaviruses
prevalent in Himachal Pradesh’. (March 27, 2017)
M.Tech. degree awarded by JUIT, Solan
2. Silky Agarwal (June 2016); Title: ‘Role of Liver X Receptor in genetic susceptibility to Vitiligo’
3. Durga Jha (June 2016); Title: ‘Role of known and predicted damaging non-synonymous Single Nucleotide
Polymorphisms of Atg5 in Asthma’.
4. Tapish Dogra; Title: ‘Business Plans for Drugs and Building Pharmaceutical Contract Manufacturers Database’.
5. Gurjinder Kaur (June 2016); Title: ‘Prediction of nsSNPs of LXR- Gene and Validation of their Role in Vitiligo
Susceptibility’.
6. Sudip Mukherjee (June 2016); Title: ‘Detection of mutations of Exons 3, 5 and 10 of CAPN3 gene from a family
suffering from calpainopathy’.
7. Lavanya Jain (June 2015); Title: ‘Mutational study of CAPN3 gene involved in Limb-Girdle Muscular Dystrophy’.
8. Kunal Passi (June 2015); Title: ‘Prevalence of interferon therapy responder/non-responder IL28b genotypes for
treatment of hepatitis c virus in North Indian population’.
Education
Ph.D. (Molecular Virology), Guru Nanak Dev University, Amritsar, India, 2001-2004
M.S. (Molecular Biology & Biochemistry), Guru Nanak Dev University, Amritsar, India, 1998-2000
Awards and Fellowships
 Rapid Grant for Young Investigators (2013-2016) from DBT, Govt. of India.
 DST-FAST Track for Young Scientists (2013-2016) from DST Govt. of India.
 Postdoctoral travel award, 2008 by American Society for Virology, US to attend 27 th American Society for Virology (ASV)
meeting at Cornell University, Ithaca, New York.
 Awarded certificate for successfully completing the course “Ethical Issues in Scientific Research”, by Louisiana State
University Health Sciences Center, Shreveport, US, March 2008.
 Senior Research Fellowship, CSIR (Council of Scientific and Industrial Research), Govt. of India, 2003.
 Travel grant by CSIR, New Delhi, India to attend European Science Foundation workshop on SNPs analysis, tools and
applications, 2003 held at Madrid, Spain.
 Junior Research Fellowship, CSIR, Govt. of India to pursue PhD, 2001.
 Qualified National Eligibility Test (NET – CSIR) to pursue doctoral research, (twice) June and December 2000.
Department of Biotechnology and Bioinformatics, JUIT, Waknaghat 173 234, H.P., India
Tel. +91 988 233 7662
 Qualified Graduate Aptitude Test of Engineering (GATE) 2000, to pursue doctoral research.
 3rd position in the university merit list in M.Sc.
Membership of Professional Bodies
 Member, Punjab Science Academy (PSA), India.
 Associate Member, American Society for Virology (ASV), US.
 Associate Member, American Society for Microbiology (ASM), US.
 Associate Member, American Society for Biochemistry and Molecular Biology (ASBMB), US.
 Member, International Society for Infectious Diseases (ISID), US.
 Life Member, Indian Virological Society (IVS), India.
 Life Member, Indian Society of Human Genetics (ISHG), India.
 Member Editorial Board of:
o International Journal of Biology, Pharmacy and Allied Sciences (ISSN: 2277-4998)
o International Journal of Research in Biosciences (ISSN: 2319–2844)
o Journal of Cell Science and Molecular Biology
o Journal of Immunology and Vaccine Technology
 Ad-Hoc Reviewer of Journals:
o Cellular and Molecular Life Sciences
o Critical Reviews in Microbiology
o Vaccine (May, 2015; outstanding reviewer)
o Journal of Clinical Virology (IF 3.0)
o PLoS one (IF 3.0)
o World journal of Gastroenterology
o Gene
o BMC Immunology (IF 2.5)
o Journal of Plant Biochemistry and Biotechnology (IF 1.5)
o BMC Research Notes
o New Horizons in Translational Medicine
o International Journal of Preventive Medicine
o European Journal of Molecular Biology
Department of Biotechnology and Bioinformatics, JUIT, Waknaghat 173 234, H.P., India
Tel. +91 988 233 7662
o International Journal of Biology
o International Journal of Genetics and Genomics
o Merit Research Journal of Medicine and Medical Sciences
Extracurricular Activities
 Attended Faculty Development Program, Jaypee University of Information Technology, Solan, Himachal Pradesh,
India; Duration 24th to 30th December 2015
 Attended Faculty Development Program, Jaypee University of Information Technology, Solan, Himachal Pradesh,
India; Duration 14th to 19th July 2014.
 Member, Mentoring Committee, Doaba College, Jalandhar for DBT Life Sciences Star College Scheme, 2013 – 2015.
 Attended 5th Winter School of Immunology held at Jodhpur, Rajasthan, India; Duration: 9th Jan -15th Jan 2012;
sponsored by ICMR, India; Indo-US Science and Technology Forum, India and Cancer Research Institute, US.
 Attended National Bio Organic Symposium 7 organized by Guru Nanak Dev University, Amritsar, Punjab, India, 2001.
 1st in Quiz competition (senior level) conducted by Department of Biotechnology, Guru Nanak Dev University, Amritsar,
on National Science Day 2000.
 2nd in Quiz competition (senior level) conducted by Department of Biotechnology, Guru Nanak Dev University, Amritsar,
on National Science Day 1999.
Publications --- (Citations)
1. Vij A, Yennamalli RM and Changotra H† (2016) Non-synonymous single nucleotide polymorphisms of ATG5
destabilize ATG12–ATG5/ATG16L1 complex: an enzyme with E3 like activity of ubiquitin conjugation system. Meta
Gene 13: 38-47. (Impact Factor: 1.27)
2. Agarwal S and Changotra H† (2017) Association of PTPN22 +1858C>T Polymorphism and Susceptibility to Vitiligo:
Systematic Review and Meta-Analysis. Indian Journal of Dermatology, Venereology and Leprology 83(2):183189. (Impact Factor: 1.5)
3. Jain S, Thakur N, Vashistt J, Grover N, Krishnan T and Changotra H† (2016) Predominance of unusual rotavirus
G1P[6] strain in North India: an evidence from hospitalized children and adult diarrheal patients. Infection,
Genetics and Evolution 46: 65-70. (Impact Factor: 3.0)
4. Randhawa R, Duseja A and Changotra H† (2016) A novel Tetra-primer ARMS-PCR based assay for genotyping
SNP rs12303764(G/T) of human Unc-51 Like Kinase 1 gene. Molecular Biology Reports 44(1):1-4. (Impact
Factor: 2.0)
5. Jain S, Vashistt J, Gupta K, Kumar A and Changotra H† (2017) Molecular analysis of VP7 gene of rotavirus G1
strains isolated from Himachal Pradesh, North India. Current Microbiology 73: 781-789. (Impact Factor: 1.6)
6. Nutan, Jain S, Shilpa, Tomar A, Changotra H and Vashistt J (2016) Computational Tools: Indispensable
Armamentarium of Medical Biotechnology. Indian Journal of Science and Technology (In Press)
Department of Biotechnology and Bioinformatics, JUIT, Waknaghat 173 234, H.P., India
Tel. +91 988 233 7662
7. Vij A, Randhawa R, Parkash J and Changotra H† (2016) Investigating regulatory signatures of human autophagy
related gene 5 (ATG5) through functional In Silico analysis. Meta Gene 9: 287-248. (Impact Factor: 1.27)
8. Agarwal S, Kaur G, Randhawa R, Mahajan V, Bansal R, and Changotra H† (2016) Liver X Receptor-α
polymorphisms (rs11039155 and rs2279238) are associated with susceptibility to Vitiligo. Meta Gene 8: 33-36.
(Impact Factor: 1.27)
9. Jain S, Nutan, Grover N, Vashistt J and Changotra H† (2016) High prevalence of rotavirus in diarrheal diseases in
Himachal Pradesh, India. VirusDisease 27: 77-83. (Impact Factor: 0.4)
10. Changotra H, Turk SM, Artigues A, Thakur NN, Gore M and Hutt-Fletcher L (2016) Epstein-Barr virus glycoprotein
gM can interact with the cellular protein p32 and knockdown of p32 impairs virus assembly. Virology 489: 223-232.
(Impact Factor: 3.4)
11. Patel SS, Mehta V, Changotra H, Udayabanu M (2016) Depression Mediates Insulin Resistance and Autophagy
Dysfunction: A Neuroprotective Role of Rosiglitazone. Hormones and Behaviour 78:200-210. (Impact Factor: 4.7)
12. Randhawa R, Sehgal M, Singh TR, Duseja A, Changotra H (2015) Unc-51 like kinase 1 (ULK1) in silico analysis for
biomarker identification: A vital component of autophagy. Gene 526(1): 40-49. (Impact Factor: 2.3) (†Corresponding
author)
13. Changotra H (2015) The Emerging Roles of Human Immunity-Related GTPase M (IRGM) Gene. International
Journal for Computational Biology 4 (1), 55-61. (ISSN/ISBN: 2278-8115)
14. Jain S, Vashistt J and Changotra H† (2014) Rotaviruses: Is their surveillance needed? Vaccine 32(27):3367-78.
(Impact Factor: 3.5) (†Corresponding author)
15. Changotra H† and Sehajpal PK (2013) An improved method for the isolation of Hepatitis B Virus DNA from human
serum. Indian Journal of Virology 24(2): 174-179. (Impact Factor: 0.4) (†Corresponding author)
16. Changotra H, Jia Y, Moore T, Liu G, Kahan SM, Sosnovtsev SV and Karst SM (2009) Type I and type II interferon
inhibit the translation of murine norovirus proteins. Journal of Virology 83: 5683-5692. (Impact Factor: 5.5)
17. Gupta V, Kumar A, Changotra H, Sarin BC and Sehajpal PK (2008) Tumor necrosis factor-α and Transforming
growth factor-β1 polymorphisms in Bronchial Asthma. Indian Journal of Medical Sciences 62 (8):323- 30. (Impact
Factor: 1.6)
18. Changotra H, Dwivedi A, Nayyar AK and Sehajpal PK (2008) Diagnosing Different Stages of Hepatitis B Infection
Using a Competitive-Polymerase Chain Reaction Assay. Indian Journal of Medical Microbiology 26 (2): 138-142.
(Impact Factor: 1.037)
19. Changotra H*, Mumphrey SM*, Moore TN, Heimann-Nichols ER, Wobus CE, Reilly MJ, Moghadamfalahi M, Shukla
D and Karst SM. (2007) Murine norovirus-1 infection is associated with histopathological changes in
immunocompetent hosts but clinical disease is prevented by STAT1-dependent interferon responses. Journal of
Virology 81: 3251-3263. (Impact Factor: 5.5) *Co-First Author.
20. Changotra H*, Dogra C*, Wedhas N*, Qin X, Wergedal JE and Kumar A (2007) TNF-Related Weak Inducer of
Apoptosis (TWEAK) is a potent skeletal muscle-wasting cytokine. The FASEB Journal 21(8):1857-69. (Impact
Factor: 7.0) *Co-First Author.
21. Dogra C, Changotra H, Wergedal J and Kumar A (2006) Regulation of phosphatidylinositol-3 kinase (PI3K)/Akt and
nuclear factor-Kappa B signaling pathways in dystrophin deficient skeletal muscles in response to mechanical
stress. Journal of Cellular Physiology 208: 575-585. (Impact Factor: 4.5)
Department of Biotechnology and Bioinformatics, JUIT, Waknaghat 173 234, H.P., India
Tel. +91 988 233 7662
22. Dogra C, Changotra H, Mohan S and Kumar A (2006) Tumor necrosis factor-like weak inducer of apoptosis
(TWEAK) inhibits myogenesis through sustained activation of Nuclear Factor-kappa B and degradation of MyoD
protein. Journal of Biological Chemistry 281 (15):10327-36. (Impact Factor: 6.0)
23. Gupta V, Sarin BC, Changotra H and Sehajpal PK (2005) Association of -308 TNF alpha polymorphism with
Bronchial Asthma in North Indian Population. Journal of Asthma 42 (10): 839-41. (Impact Factor: 1.9)
24. Changotra H and Sehajpal PK (2005) Quantitative Detection of Serum HBV DNA Levels Employing a New S gene
Based cPCR Assay. Archives of Virology 150 (3): 481-91. (Impact Factor: 2.3)
25. Mohindru K, Changotra H and Sehajpal PK (2004) Lack of association between TNF alpha -308 polymorphism and
End Stage Renal Disease in North Indian Population. International Journal of Human Genetics 4 (1): 61-64.
(ISSN/ISBN 09723757)
26. Changotra H and Sehajpal PK (2004) Development of S-gene based PCR for detection of hepatitis B virus. Indian
Journal of Veterinary Pathology 28 (1): 4-6. (ISSN/ISBN 0250-4758)
Genbank Submissions (Total Accesssion No. : 23)
1. Thakur N, Grover N, Changotra H and Vashistt J (2017) Escherichia coli intimin gene, partial cds. Accession
Number: KX911252
2. Thakur N, Grover N, Changotra H and Vashistt J (2017) Escherichia coli bundle forming protein gene, partial cds.
Accession Number: KX911251
3. Thakur N, Changotra H, Grover N and Vashistt J (2017) Vibrio sp. strain cholera 16S ribosomal RNA gene, partial
sequence. Accession Number: KX891575
4. Thakur N, Grover N, Changotra H and Vashistt J (2017) Escherichia coli ATP binding cassette transporter gene,
partial cds. Accession Number: KX911253
5. Thakur N, Grover N, Changotra H and Vashistt J (2017) Escherichia coli heat-labile enterotoxin protein beta chain
OS gene, partial cds. Accession Number: KX911254
6. Jain S and Changotra H (2016) VP4 and VP7 sequences of Rotavirus clinical isolates (JU-SOL-173, JU-SHI-14,
JU-SOL-5, JU-SOL58, and JU-SOL-77) from patients having diarrhea from Himachal Pradesh. Accession Number:
KP938512 to KP938519, KM880063 and KM880064 (Total GenBank Acc. No. = 10).
7. Changotra H, Pathak D, Chandy SP and Ali S (2005) Bubalus bubalis clone pHR2 satellite sequence. Accession
Number: DQ020282.1
8. Changotra H and Ali S (2005) Bubalus bubalis clone PHSR1.3 satellite sequence. Accession Number: AY940196.1.
9. Changotra H and Ali S (2005) Bubalus bubalis clone pHR.652 satellite sequence. Accession Number: AY873795.1.
10. Changotra H and Ali S (2005) Bubalus bubalis clone pDS4.2 satellite sequence. Accession Number: AY960121.1.
11. Changotra H and Ali S (2005) Bubalus bubalis clone pDS4.1 satellite sequence. Accession Number: AY956327.1.
12. Pathak D, Changotra H and Ali S (2005) Bubalus bubalis clone pDR.339 satellite sequence. Accession Number:
DQ131586.1.
13. Pathak D, Changotra H and Ali S (2005) Bubalus bubalis clone pDS5.4 satellite sequence. Accession Number:
DQ022072.1.
Department of Biotechnology and Bioinformatics, JUIT, Waknaghat 173 234, H.P., India
Tel. +91 988 233 7662
14. Kalyani M, Kaur J, Changotra H, Kajal N, Sarin BC and Sehajpal PK (2005) Mycobacterium tuberculosis isolate
North Indian genomic sequence. Accession Number: DQ120517.1.
Presentatiaons in Conferences
1. Singh S, Seam RK, Gupta MK, Yennamalli RM, Changotra H (2017) Prediction of Genetic marker in E2F1 Gene by
a Computational Approach. 42nd Annual Meeting of the Indian Society of Human Genetics & International
Symposium on Trends in Human Genetic Research & Management, Indian Institute of Sciences, Bangalore, 24 March, 2017.
2. Vij A and Changotra H (2017) Role of Autophagy related gene 5 (ATG5) single nucleotide polymorphism rs2245214
(C/G) with HBV susceptibility in North Indian population. International Conference on Recent Research in
Biomedical Engineering, Cancer Biology, Stem Cells, Bioinformatics and Applied Biotechnology (BECBAB2017). Jawaharlal Nehru University, New Delhi, 25 February, 2017].
3. Sharma A, Duseja A, Changotra H (2017) Association of IRGM promoter polymorphisms with hepatitis B virus
infection in North Indian population. 42nd Annual Meeting of the Indian Society of Human Genetics &
International Symposium on Trends in Human Genetic Research & Management, Indian Institute of Sciences,
Bangalore, 2-4 March, 2017.
4. Sharma A, Duseja A and Changotra H (2017) Association of IRGM gene variant rs4958842 with Hepatitis B
infection in North Indian population. 20th Punjab Science Congress, IET Bhaddal, Ropar, Punjab, 7-9 February
2017.
5. Sharma A and Changotra H (2017) Mutagenic primer based PCR-RFLP assays for genotyping of three promoter
region SNPs (rs4958842, rs4958843 and rs4958846) of IRGM gene. 20th Punjab Science Congress, IET
Bhaddal, Ropar, Punjab, 7-9 February 2017.
6. Singh S, Seam RK, Gupta MK, Changotra H (2017) Association of G393S Variant of E2F1 gene with Lung and
HNC cancer risk in North Indian Population. 20th Punjab Science Congress, IET Bhaddal, Ropar, Punjab, 7-9
February 2017.
7. Changotra H (2016) Host Genetics and Hepatitis B Virus infection. International symposium on Genomic
Medicine: personalized care for me and you, Doaba College Jalandhar, Punjab, India, 18 October 2016.
8. Dogra T, Mukherjee S, Joshi V, Khosla R and Changotra H (2015) Role of genetic variants in Autophagy related
gene 7 (Atg7) (rs35807939) in Asthma in North Indian population. National Conference on Recent Trends in
Biomedical Engineering, Cancer Biology, Bioinformatics and Applied Biotechnology (BECBAB-2015),
Jawaharlal Nehru University, New Delhi, 28 November 2015.
9. Vij A and Changotra H (2015) In silico prediction and analysis of non synonymous single nucleotide polymorphisms
(nsSNPs) in autophagy related gene 5 (ATG5). National Conference on Recent Trends in Biomedical
Engineering, Cancer Biology, Bioinformatics and Applied Biotechnology (BECBAB-2015), Jawaharlal Nehru
University, New Delhi, 28 November 2015.
10. Sharma A, Duseja A and Changotra H (2015) Association of autophagy gene Atg16L1 variant rs2241879 and
Chronic Hepatitis B in North Indian population. National Conference on Recent Trends in Biomedical
Engineering, Cancer Biology, Bioinformatics and Applied Biotechnology (BECBAB-2015), Jawaharlal Nehru
University, New Delhi, 28 November 2015.
Department of Biotechnology and Bioinformatics, JUIT, Waknaghat 173 234, H.P., India
Tel. +91 988 233 7662
11. Jha D, Joshi V, Sharma A, Khosla R and Changotra H (2015) Autophagy Related Gene 5 (Rs17587319) Variants in
Asthmatic Patients in North Indian Population. 6th World Congress on Biotechnology, New Delhi, India, 05-07
October, 2015.
12. Jain S, Vashistt J and Changotra H (2015) Predominance of Rotavirus G1P[6] strain in Himachal Pradesh, India.
The 5th Asian Vaccine Conference, Hanoi, Vietnam, 12-14 June 2015.
13. Jain S, Singh TR, Vashistt J and Changotra H (2015) Molecular analysis of G1 rotavirus strains isolated from
Himachal Pradesh. National Conference on Emerging Trends in Host-Microb Interactions, DAV University
Jalandhar, Punjab, 17th-18th April 2015. (2nd best Poster presentation award)
14. Batta R, Poonam, Changotra H, Shrivastava R and Vashistt J (2015). Assessment of the resistance pattern in
Klebsiella spp. against β-lactams in Himachal Pradesh. National Conference on Emerging Trends in HostMicrob Interactions, DAV University Jalandhar, Punjab, 17th-18th April 2015.
15. Jain S, Kumar N, Nutan, Vashistt J and Changotra H (2014) Phylogenetic analysis to study the evolution of
Rotavirus G1P[6] strain isolated from Himachal Pradesh. International Conference on “Stem Cell Research,
Cancer Biology, Biomedical Sciences, Bioinformatics and Applied Biotechnology, Jawaharlal Nehru
University, New Delhi, India, 1st -2nd November, 2014.
16. Nutan, Jain S, Grover N, Kumar Y, Changotra H and Vashistt J (2014) Identification, characterization of prevalent
diarrheagenic bacterial pathogens from regions of Himachal Pradesh. International Conference on Life science
Biotechnology & Bioinformatics, Jaypee Institute of Information Technology, Noida, India, September, 2014. (2 nd
best Poster presentation award) Indo Global Journal of Pharmaceutical Sciences, 2014; 4(3): 169. (2nd best
Poster presentation award)
17. Randhawa R, Sehgal M, Singh TR, Duseja A and Changotra H (2014) Computational analysis of unc-51 like kinase
1 (ULK1) gene and its association with autophagy. International Conference on “Stem Cell Research, Cancer
Biology, Biomedical Sciences, Bioinformatics and Applied Biotechnology, Jawaharlal Nehru University, New
Delhi, India, 1st -2nd November, 2014.
18. Randhawa R and Changotra H (2014) Interleukin-28B SNPs rs12979860 and rs8099917 allele frequencies from
North India using a novel in-house multiplex T-ARMS-PCR. International Conference on “Stem Cell Research,
Cancer Biology, Biomedical Sciences, Bioinformatics and Applied Biotechnology, Jawaharlal Nehru
University, New Delhi, India, 1st -2nd November, 2014.
19. Randhawa R and Changotra H (2014) A Novel Multiplex T-ARMS-PCR Assay to Genotype IL28B Single Nucleotide
Polymorphisms rs12979860 and rs8099917 Simultaneously. New insights into Pharmacogenomics, Drug
Development and Personalized Medicine, Bhagwan Mahavir Medical Research Institute, Hyderabad, India, July
18 – 19, 2014. (2nd best Poster presentation award)
20. Changotra H, Artigues A and Hutt-Fletcher L (2010) The cellular protein p32 interacts with the cytoplasmic tail of
EBV gM and is required for efficient egress of virions from the cell. 35th International Herpes Virus Workshop,
Salt Lake City, Utah, July 24 – 29, 2010.
21. Changotra H and Karst SM (2008) Both type I and type II interferon block the translation of murine norovirus
proteins independently of PKR. 27th American Society of Virology Annual Conference, Cornell University,
Ithaca, New York July 12-16, 2008.
22. Changotra H and Karst SM (2007) Interferon-dependent mechanisms of MNV-1 replication inhibition. 26th
American Society of Virology Annual Conference Corvallis, Oregon, US on July 14-18, 2007.
Department of Biotechnology and Bioinformatics, JUIT, Waknaghat 173 234, H.P., India
Tel. +91 988 233 7662
23. Changotra H, Dwivedi A, Nayyar AK and Sehajpal PK (2006) Diagnosing Different Stages of Hepatitis B Virus
Infection from its Load in the Serum of the Patients. International Meeting of the Molecular Biology of Hepatitis
B Viruses (HBV 2006) Vancouver, Canada, September 17-20, 2006. #97.
24. Mumphrey S, Moore TN, Heimann E, Changotra H and Karst SM (2006). Murine norovirus 1 infection in the
intestine and in peripheral tissues is controlled by interferon responses through several mechanisms. Biennial
Institutional Development Award Program Symposium, Washington D.C. Poster.
25. Mumphrey SM, Moore TN, Heimann-Nichols ER, Changotra H, and Karst SM (2006) MNV-1 local and systemic
infection is inhibited by interferon through multiple mechanisms. Fondation Merieux Conference: Vaccine
Interference Annecy, Les Pensieres, France, 2006.
26. Dogra C, Changotra H and Kumar A (2006) Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) inhibits
skeletal myogenesis through sustained activation of Nuclear Factor-kappa B and degradation of MyoD protein.
Experimental Biology San Frascisco, California on April 1-5, 2006. #236.26 (FASEB J 2006; 20:A392).
27. Kumar A, Dogra C and Changotra H (2006) PI3K/Akt signaling pathway contributes to the activation of NF-kappaB
transcription factor in dystrophin-deficient skeletal muscles in response to mechanical stress. Experimental
Biology San Frascisco, California on April 1-5, 2006. #483.7. (FASEB J 2006;20:A802)
28. Kumar A, Gupta V, Changotra H, Sarin BC and Sehajpal PK (2005) G-308A TNF-alpha and C-509T TGF-beta
polymorphisms in Bronchial Asthma. Presented at Genes, Evolution and Complex diseases: an international
symposium on human origins and genetics held at NCBS, Bangalore, India on February 17-19, 2005.
29. Changotra H and Sehajpal PK (2004) Development of S-Gene Based Competitive-Polymerase Chain Reaction for
Quantification of HBV DNA. Paper presented at 7th Punjab Science Congress Guru Nanak Dev University,
Amritsar, India on February 7-9, 2004.
30. Changotra H, Mohindru K and Sehajpal PK (2003) Single Nucleotide Polymorphism at -308 site in TNF-alpha Gene
Promoter in End Stage Renal Disease Patients from North India. European Science Foundation Workshop on
SNPs analysis, tools and applications Madrid, Spain on November 28-29, 2003.
Invited Talks/Lectures

“Murine Norovirus-1: A Model System to Study Norovirus Pathobiology” (Feb., 2009) at National Institute of
Science Education and Research (NISER), Bhubaneswar, India.

“Murine Norovirus-1: Role of Interferons in its Replication Inhibition” (Oct., 2010) at Indian Institute of Chemical
Biology (IICB), Kolkata, India.

“Murine Norovirus-1: A New Player in the Field of Norovirus Biology” (June 21, 2013) at Institute of Microbioal
Technology, Chandigarh.
“Norovirus pathogenesis and role of interferon signaling in replication inhibition” at RGCB, Trivandrum.


“Moecular Biology Techniques” invited talk cum workshop at Doaba College, Janandhar, Punjab (9 th April
2016).

“Host genetics and hepatitis B virus infection” (October 18, 2016) International Symposium on Genomic Medicine:
personalized care for me and you; Doaba College, Jalandhar, Punjab, India.
Department of Biotechnology and Bioinformatics, JUIT, Waknaghat 173 234, H.P., India
Tel. +91 988 233 7662