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Supplemental Citations AUSTIN, J., and J. KIMBLE, 1987 glp-1 is required in the germ line for regulation of the decision between mitosis and meiosis in C. elegans. Cell 51: 589-599. BEANAN, M. J., and S. STROME, 1992 Characterization of a germ-line proliferation mutation in C. elegans. Development 116: 755-766. BEITEL, G. J., S. G. CLARK and H. R. HORVITZ, 1990 Caenorhabditis elegans ras gene let60 acts as a switch in the pathway of vulval induction. Nature 348: 503-509. CHIN, G. M., and A. M. VILLENEUVE, 2001 C. elegans mre-11 is required for meiotic recombination and DNA repair but is dispensable for the meiotic G(2) DNA damage checkpoint. Genes Dev 15: 522-534. CLIFFORD, R., M. H. LEE, S. NAYAK, M. OHMACHI, F. GIORGINI et al., 2000 FOG-2, a novel F-box containing protein, associates with the GLD-1 RNA binding protein and directs male sex determination in the C. elegans hermaphrodite germline. Development 127: 5265-5276. GARTNER, A., S. MILSTEIN, S. AHMED, J. HODGKIN and M. O. HENGARTNER, 2000 A conserved checkpoint pathway mediates DNA damage--induced apoptosis and cell cycle arrest in C. elegans. Mol Cell 5: 435-443. GRANT, B., and D. HIRSH, 1999 Receptor-mediated endocytosis in the Caenorhabditis elegans oocyte. Mol Biol Cell 10: 4311-4326. HAN, M., and P. W. STERNBERG, 1990 let-60, a gene that specifies cell fates during C. elegans vulval induction, encodes a ras protein. Cell 63: 921-931. 1 HAN, M., and P. W. STERNBERG, 1991 Analysis of dominant-negative mutations of the Caenorhabditis elegans let-60 ras gene. Genes Dev 5: 2188-2198. HANSEN, D., E. J. HUBBARD and T. SCHEDL, 2004 Multi-pathway control of the proliferation versus meiotic development decision in the Caenorhabditis elegans germline. Dev Biol 268: 342-357. HSU, V., C. L. ZOBEL, E. J. LAMBIE, T. SCHEDL and K. KORNFELD, 2002 Caenorhabditis elegans lin-45 raf is essential for larval viability, fertility and the induction of vulval cell fates. Genetics 160: 481-492. JONES, A. R., R. FRANCIS and T. SCHEDL, 1996 GLD-1, a cytoplasmic protein essential for oocyte differentiation, shows stage- and sex-specific expression during Caenorhabditis elegans germline development. Dev Biol 180: 165-183 KORNFELD, K., K. L. GUAN and H. R. HORVITZ, 1995 The Caenorhabditis elegans gene mek-2 is required for vulval induction and encodes a protein similar to the protein kinase MEK. KUWABARA, P. E., M. H. LEE, T. SCHEDL and G. S. JEFFERIS, 2000 A C. elegans patched gene, ptc-1, functions in germ-line cytokinesis. Genes Dev 14: 1933-1944. LACKNER, M. R., K. KORNFELD, L. M. MILLER, H. R. HORVITZ and S. K. KIM, 1994 A MAP kinase homolog, mpk-1, is involved in ras-mediated induction of vulval cell fates in Caenorhabditis elegans. Genes Dev 8: 160-173. LACKNER, M. R., and S. K. KIM, 1998 Genetic analysis of the Caenorhabditis elegans MAP kinase gene mpk-1. Genetics 150: 103-117. 2 LEE, M. H., and T. SCHEDL, 2001 Identification of in vivo mRNA targets of GLD-1, a maxi-KH motif containing protein required for C. elegans germ cell development. Genes Dev 15: 2408-2420. LEACOCK, S. W., and V. REINKE, 2006 Expression profiling of MAP kinase-mediated meiotic progression in Caenorhabditis elegans. PLoS Genet 2: e174. NAVARRO, R. E., E. Y. SHIM, Y. KOHARA, A. SINGSON and T. K. BLACKWELL, 2001 cgh1, a conserved predicted RNA helicase required for gametogenesis and protection from physiological germline apoptosis in C. elegans. Development 128: 32213232. OHMACHI, M., C. E. ROCHELEAU, D. CHURCH, E. LAMBIE, T. SCHEDL et al., 2002 C. elegans ksr-1 and ksr-2 have both unique and redundant functions and are required for MPK-1 ERK phosphorylation. Curr Biol 12: 427-433. PASIERBEK, P., M. JANTSCH, M. MELCHER, A. SCHLEIFFER, D. SCHWEIZER et al., 2001 A Caenorhabditis elegans cohesion protein with functions in meiotic chromosome pairing and disjunction. Genes Dev 15: 1349-1360. ROGALSKI, T. M., D. G. MOERMAN and D. L. BAILLIE, 1982 Essential genes and deficiencies in the unc-22 IV region of Caenorhabditis elegans. Genetics 102: 725-736. SCHUMACHER, J. M., A. GOLDEN and P. J. DONOVAN, 1998 AIR-2: An Aurora/Ipl1related protein kinase associated with chromosomes and midbody microtubules is required for polar body extrusion and cytokinesis in Caenorhabditis elegans embryos. J Cell Biol 143: 1635-1646. 3 WU Y, H. M., GUAN KL., 1995 MEK-2, a Caenorhabditis elegans MAP kinase kinase, functions in Ras-mediated vulval induction and other developmental events. Genes Dev. 15: 742-755. WU, Y., and M. HAN, 1994 Suppression of activated Let-60 ras protein defines a role of Caenorhabditis elegans Sur-1 MAP kinase in vulval differentiation. Genes Dev 8: 147-159. ZETKA, M. C., I. KAWASAKI, S. STROME and F. MULLER, 1999 Synapsis and chiasma formation in Caenorhabditis elegans require HIM-3, a meiotic chromosome core component that functions in chromosome segregation. Genes Dev 13: 2258-2270. 4