Download Powerpoint - Blood Journal

Survey
yes no Was this document useful for you?
   Thank you for your participation!

* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project

page
1
page
2
page
3
page
4
page
5
page
6
page
7
page
8
Document related concepts
no text concepts found
Transcript 
Comparative analysis of human ex vivo–generated
platelets vs megakaryocyte-generated platelets in mice: a
cautionary tale
by Yuhuan Wang, Vincent Hayes, Danuta Jarocha, Xiuli Sim, Dawn C. Harper, Rudy
Fuentes, Spencer K. Sullivan, Paul Gadue, Stella T. Chou, Beverly J. Torok-Storb,
Michael S. Marks, Deborah L. French, and Mortimer Poncz
Blood
Volume 125(23):3627-3636
June 4, 2015
©2015 by American Society of Hematology
Infused human donor platelets and EV-megakaryocytes from different developmental stages into
NSG mice.
Yuhuan Wang et al. Blood 2015;125:3627-3636
©2015 by American Society of Hematology
Histologic examination of the lungs and spleens after infusion of AMC EV-megakaryocytes into
NSG mice.
Yuhuan Wang et al. Blood 2015;125:3627-3636
©2015 by American Society of Hematology
Size distribution of platelets in recipient mice.
Yuhuan Wang et al. Blood 2015;125:3627-3636
©2015 by American Society of Hematology
Characterization young vs old platelets.
Yuhuan Wang et al. Blood 2015;125:3627-3636
©2015 by American Society of Hematology
Rapid clearance of small human platelets.
Yuhuan Wang et al. Blood 2015;125:3627-3636
©2015 by American Society of Hematology
In situ studies of incorporation of TO+ vs TO− platelets into growing thrombi.
Yuhuan Wang et al. Blood 2015;125:3627-3636
©2015 by American Society of Hematology
Analysis of AMC EV-PLP preparation.
Yuhuan Wang et al. Blood 2015;125:3627-3636
©2015 by American Society of Hematology
Related documents