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Decreasing RGS3myc expression relieves inhibition of Ins(1,4,5)P3 generation. a, immunoblot showing increasing transient expression of RGS3myc in HEK293/M3 cells with increasing amounts of RGS3myc DNA. The blot is representative of blots from three different transient transfections. b, increasing the level of RGS3myc expression in HEK293/M3 cells leads to a decreased level of Ins(1,4,5)P3 production. Stephen C. Tovey, and Gary B. Willars Mol Pharmacol 2004;66:1453-1464 The American Society for Pharmacology and Experimental Therapeutics
