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Some factors involved in chromosomal segregation which are relevant to understanding chromosomal instability (CI) and aneuploidy. CI syndromes include Bloom syndrome (OMIM 210900) and others. (Based on Thompson SL et al: Mechanisms of chromosomal instability. Curr Biol 2010;20(6):R285). Source: Chapter 55. Cancer: An Overview, Harper's Illustrated Biochemistry, 29e Citation: Murray RK, Bender DA, Botham KM, Kennelly PJ, Rodwell VW, Weil P. Harper's Illustrated Biochemistry, 29e; 2012 Available at: http://mhmedical.com/ Accessed: August 03, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved