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FABP4 , 1-132aa
Human, Recombinant, E.coli
Cat. No. FAB0802
Cat. No. FAB0852
Size: 0.5 mg
Size: 100 ug
Full name: Fatty acid binding protein 4
NCBI Accession No.: NP_001433
Synonyms: ap2, A-FABP
Description: FABP4 (Fatty acid binding protein 4) is expressed in adipocytes and macrophages, and
integrates inflammatory and metabolic responses. FABP4 is thought to regulate fatty acid uptake, release, and
storage in adipocytes and participates in systemic glucose homeostasis and in macrophage responses in
atherosclerosis. Blocking this protein either through genetic engineering or drugs has the possibility of treating
heart disease, diabetes, asthma, obesity, and fatty liver disease. Recombinant FABP4 protein was expressed
in E.coli and purified by using conventional chromatography techniques.
Form: Liquid in 20 mM Tris pH 7.5, 2 mM EDTA, 10% glycerol
Molecular Weight: 14 kDa (132 aa)
Purity: > 95% by SDS-PAGE
Concentration: 1 mg/ml
Sequences: MCDAFVGTWK LVSSENFDDY MKEVGVGFAT RKVAGMAKPN MIISVNGDVI
TIKSESTFKN TEISFILGQE FDEVTADDRK VKSTITLDGG VLVHVQKWDG
KSTTIKRKRE DDKLVVECVM KGVTSTRVYE RA
General references:
Furuhashi M., et al. (2007).Nature. 21:447(7147):959-65
Shum BO., et al. (2006).J Clin Invest. 116(8):2183-2192
Storage: Store at -20℃. Avoid freeze/thaw cycle
15% SDS-PAGE(3μg)