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Genistein, the Isoflavone in Soybean, Causes Amyloid Beta Peptide
Accumulation in Human Neuroblastoma Cell Line: Implications in
Alzheimer#cod#x02019;s Disease
Gargi Chatterjee;Debashree Roy;Vineet Kumar Khemka;Mrittika Chattopadhyay;Sasanka Chakrabarti#cod#x0002A;;
Department of Biochemistry, Institute of Post Graduate Medical Education and Research, 244 AJC Bose Road, Kolkata-700020, India. ;
Figure 5. Immunoassay of A#cod#x003B2;42. Amyloid #cod#x003B2;42 in the cell lysate as well as that released in the culture medium was measured as described in
#cod#x02018;MATERIALS AND METHODS#cod#x02019; from control and genistein 20 #cod#x000B5;M treated SHSY5Y cells. A. Released A#cod#x003B2;42 extracellular in
culture supernatant. B. Intracellular A#cod#x003B2;42 in cell lysate. The results are the mean #cod#x000B1; SEM of four experimental observations. Statistically significant,
#cod#x003D5; p#cod#x0003C; 0.01 vs. control; #cod#x003A8; p#cod#x0003C; 0.05 vs. control.
Aging and Disease,null,6(6),456-465. Doi:10.14336/AD.2015.0327
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