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Program Director/Principal Investigator (Last, First, Middle):
Lee, Susan Jung-Ah
BIOGRAPHICAL SKETCH
Provide the following information for the Senior/key personnel and other significant contributors in the order listed on Form Page 2.
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NAME
POSITION TITLE
LEE, SUSAN JUNG-AH
ASSISTANT PROFESSOR OF MEDICINE
eRA COMMONS USER NAME (credential, e.g., agency login)
SUSANLEEMD
EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and
residency training if applicable.)
DEGREE
INSTITUTION AND LOCATION
MM/YY
FIELD OF STUDY
(if applicable)
The Ohio State University, Columbus, OH
B.A.
9/89-6/93
Chemistry
Case Western Reserve University School of
Medicine, Cleveland, OH
M.D.
8/93-5/97
Medicine
A. Personal Statement
The focus of my research has been evaluating methods to improve the quality of care for rheumatoid arthritis
patients and gout. I have also been extensively involved in designing and implementing clinical trials for
patients with various autoimmune, rheumatological conditions. Our preliminary studies have demonstrated the
feasibility and validity of computer- and web-based program in assessing the levels of disease activity among
RA patients. We propose to use a similar program to improve the medication adherence among RA patients..
As both principal and subinvestigator for more than 50 clinical trials at the UCSD Center for Innovative
Therapy, I have an extensive experience addressing unforeseen difficulties related clinical trials including
recruitment, drop-outs, and data management.
B. Positions and Honors
Positions and Employment
6/97-6/00 Internal Medicine Internship and Residency, full-time
University of California San Diego, San Diego, CA (UCSD)
7/00-6/01 Internal Medicine Chief Resident (inpatient), full-time; UCSD
7/00-7/02 General Internist, part-time; Veterans Affairs Medical Center, La Jolla, CA
7/00-5/05 General Internist, part-time; San Diego County Jail Medicine Clinic, San Diego, CA
7/01-6/04 Rheumatology Fellowship; Division of Rheumatology, Allergy, and Immunology, UCSD
7/04-6/05 Rheumatology Post-doctorate Fellowship
Division of Rheumatology, Allergy, and Immunology, UCSD
7/01-Pres Rheumatologist; part-time
Arthritis Foundation sponsored Clinic at St. Vincent/DePaul and Logan Heights, San Diego, CA
8/02-Pres Principal and Co-Investigator for clinical trials; Center for Innovative Therapy, UCSD
7/05-6/06 Assistant Clinical Professor; Division of Rheumatology, Allergy, and Immunology, UCSD
12/05-Pres Interdisciplinary Liaison; Clinical Investigation Institute – Clinical Trials Unit, UCSD
7/06-Pres Assistant Adjunct Professor; Division of Rheumatology, Allergy, and Immunology, UCSD;
VA San Diego Healthcare System Division of Health Services Research and Development;
Other Experiences and Professional Membership
9/93-5/97 American Medical Association, American Medical Student Association
6/00
Speaker for the Dept of Medicine Grand Rounds (UCSD)
8/00
American Board of Internal Medicine Certification – Internal Medicine
6/00-6/01 Mentor for Internal Medicine Residency Big Sib Program (UCSD)
11/03
American Board of Internal Medicine Certification - Rheumatology
4/04-6/04 Project Assistance for UCSD Faculty Mentor Program
1/03-1/05 Participant of Clinical Research Enhancement through Supplemental Training (UCSD)
6/00-Pres Preceptor for Introductory to Clinical Medicine Course (UCSD)
PHS 398/2590 (Rev. 06/09)
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Biographical Sketch Format Page
Program Director/Principal Investigator (Last, First, Middle):
7/01-Pres
4/05-5/07
7/05-6/09
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2006
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2007
7/07-Pres
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2008
2008
2009
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2009-Pres
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2010
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2010-Pres
Honors
1989-1993
1990
1993
2001
2002
Lee, Susan Jung-Ah
American College of Rheumatology
Arthritis Foundation (2010 San Diego Arthritis Walk Honoree)
Case Western Reserve University Medical Alumni Leadership Council
Instructor for UCSD Rheumatology Teaching Rounds for Medicine Resident’s Morning Report
Faculty Interviewer for the UCSD Rheumatology Fellowship Applicants
Faculty Interviewer for the UCSD Internal Medicine Residency Applicants
Faculty Speaker for UCSD CME Topics and Advances in Internal Medicine Course (3/06),
Pediatric Academic Society Annual Meeting (4/06), UCSD Rheumatic Diseases Core Center
Conference (10/06), San Diego Arthritis Foundation Primary Care Physicians Conference
(11/06)
Peer Reviewer for Multiple Medical Journals including but not limited to Arthritis and
Rheumatism, Journal of Rheumatology, Journal of American Medical Association, Lancet,
Arthritis Care and Research
American College of Rheumatology Annual Scientific Meeting Abstract Reviewer
Clinical Investigation Institute (CII) Information Technology Systems Committee
Committee Chair (2009) and Member for UCSD School of Medicine Independent Study
Program (ISP)
Faculty Mentor for Hepatitis B Screening Elective, initiative by the Asian Pacific American
Medical Student Association (UCSD)
Faculty Speaker for the Korean Health Fair (5/07), American College of Physicians Annual
Meeting (10/07), UCSD The Year in Rheumatology Conference (12/07)
Co-Director of the UCSD Introductory to Clinical Medicine- Rheumatology
Faculty Writer for the San Diego Arthritis Foundation Newsletter
UCSD School of Medicine Recruitment and Admissions Committee Member and Interviewer
Faculty Speaker for the UCSD SOM Internal Medicine Interest Group (3/08), Moving Beyond
Targeted Therapies: Targeted Management of Rheumatoid Arthritis CME-certified visiting
faculty program (3/08), San Diego VAMC Dept of Nutrition (4/08)
NIH Reviewer for “Autoimmune Centers of Excellence” RFA/Grant
Faculty Speaker for UCSD CME Topics and Advances in Internal Medicine Course (3/09),
UCSD Internal Medicine Noon Conference Speaker (1/09, 11/09, 12/09)
Search Committee for UCSD Division of Rheumatology/Orthopedics Faculty Recruitment
Faculty Mentor for Class of 2013 UCSD School of Medicine Medical Student Scholars
Faculty Mentor for UCSD Medical Scholars Program
Southern California Rheumatology Consortium
Faculty Speaker for the UCSD Rheumatic Diseases Core Center Conference (5/10)
Faculty Mentor for UCSD Phi Delta Epsilon Mentorship Program
UCB Rheumatoid Arthritis Scholarship Program Selection Committee Member
UCSD Division of Rheumatology White Papers Subcommittee Co-Leader on Teaching
Prestigious Minority Scholarship, The Ohio State University, Columbus, OH
Scarlet and Gray Scholarship, The Ohio State University, Columbus, OH
Summa Cum Laude, The Ohio State University, Columbus, OH
Wyeth-Ayerst sponsored American College of Rheumatology (ACR) Fellow
1 of 10 Rheumatology Fellows selected for the NYU Seminars in Advance Rheumatology
Travel Award for ACR State of the Art Conference
2003
1 of 25 Rheumatology Fellows selected for Amgen Rheumatology Fellowship
Recipient of 2003 ACR Rheumatology Fellow Awards
2004
1 of 10 Rheumatology Fellows selected for the NYU Seminars in Advance Rheumatology
The Federation of Clinical Immunology Societies (FOCIS) 2004 Travel Award
Travel Award for FOCIS Centers of Excellence Trainee Satellite Symposium
2004-2006 Recipient of the National Institute of Health Loan Repayment Program
2006
San Diego VA Medical Center Honorary Dietitian (Awarded to 1 VA faculty who has
demonstrated commitment to incorporating nutrition in the treatment of medical diseases)
2006
Moderator for the 2006 ACR Annual Scientific Meeting
PHS 398/2590 (Rev. 06/09)
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Biographical Sketch Format Page
Program Director/Principal Investigator (Last, First, Middle):
2007
2008
2009
Lee, Susan Jung-Ah
UCSD Health Sciences Academic Senate Research Award
1 of 25 Finalist for Robert Wood Johnson Foundation Physician Faculty Scholars Program
Honorable Mention UCSD Rheumatology Fellowship Teaching Award
Honoree for 2010 San Diego Arthritis Foundation Walk
C. Peer-reviewed publications (in chronological order)
Publications
1. Lee S J-A, Kavanaugh A. Pharmacological treatment of established rheumatoid arthritis. Best Pract Res
Clin Rheumatol. 2003;17(5):811-829.
2. Lee SJ, Yedla P, Kavanaugh A. Secondary immune deficiencies associated with biological therapeutics.
Cur Allergy Asthma Rep 2003;3(5):389-395.
3. Lee SJ, Lenert L, Kavanaugh A. Internet based monitoring of patients with rheumatoid arthritis. Clin Exp
Rheumatol. 2004;22(5):S34-S38.
4. Lee SJ, Kavanaugh A. A need for greater reporting of socioeconomic status and race in clinical trials. Ann
Rheum Dis 2004;63(12):1700-01.
5. Lee SJ, Kavanaugh A. Adalimumab for the treatment of rheumatoid arthritis. Therapy 2005;2(1):13-21.
6. Lee SJ, Kavanaugh A. Adverse reactions to biologic agents: focus on autoimmune disease therapies. J
Allergy Clin Immunol 2005;116(4):900-05.
7. Lee SJ, Lenert L, Weisman S, Kavanaugh A. Factors affecting rheumatoid arthritis patients’ decisions to
participate in clinical trials. J Rheumatol 2005;32(12):2317-25.
8. Lee SJ, Kavanaugh A. Mini-Primer on Allergic and Immunological Diseases: Autoimmunity, Vasculitis,
Autoantibodies. J Allergy Clin Immunol 2006;117(2 Suppl Mini-Primer):S445-50.
9. Lee SJ, Kavanaugh A. Biologic agents in rheumatology: safety considerations. Rheum Dis Clin Updates.
2006;32(Suppl 1):3-10.
10. Lee SJ, Terkeltaub RA, Kavanaugh A. Recent developments in diet and gout. Curr Opin Rheumatol
2006;18(2):193-98.
11. Lee SJ, Terkeltaub RA. New developments in mechanisms and treatment of hyperuricemia. Curr
Rheumatol Rep 2006;8(3):224-30.
12. Lee SJ, Terkeltaub RA. Clinical trials review: Does diet contribute to the development of hyperuricemia.
Curr Rheumatol Rep 2006;8(3):207-08.
13. Lee SJ, Kavanaugh A. Diagnosis and treatment of established rheumatoid arthritis. Medscape
Rheumatology August 16, 2006. Accessed at http://www.medscape.com/viewprogram/5830 (July 1, 2008).
14. Bussel J, Giulina L, Lee S, Sandborg C, Patel VL, Stiehm ER. Update on monoclonal antibodies. Curr
Probl Pediatr Adolesc Health Care. 2007;37(4):118-35.
15. Cassell SE, Bieber JD, Rich P, Tutuncu ZN, Lee SJ, Kalunian KC, Wu CW, Kavanaugh A. The modified
Nail Psoriasis Severity Index: validation of an instrument to assess psoriatic nail involvement in patients
with psoriatic arthritis. J Rheumatol 2007;34(1):123-29.
16. Lee SJ, Lenert L, Kavanaugh A. Electronic and computer generated patient questionnaires in standard
care. Best Pract Res Clin Rheumatol 2007;21(4):637-47.
17. Kavanaugh A, Rosengren S, Lee SJ, Hammaker D, Firestein G, Kalunian K, Wei N, Boyle DL. Assessment
of rituximab’s immunomodulatory synovial effects (the ARISE trial) I: clinical and synovial biomarker
results. Ann Rheum Dis 2008;67(3):402-8.
18. Lee SJ, Kavanaugh AF. Monoclonal antibodies and fusion proteins. In: Rich RR, Fleisher TA, Shearer WT,
Schroeder HW Jr, Frew AJ, Weyand CM, editors. Clinical Immunology: Principles and practice.
Philadelphia: Mosby Elsevier; 2008:1405-16.
19. Hirsch J, Lee S, Terkeltaub R, Khanna D, Singh J, Sarkin A, Harvey J, Kavanaugh A. Evaluation of an
instrument assessing gout impact on health-related quality of life. J Rheumatol 2008:35(12);2406-14.
20. Lee SJ, Chang H, Yazici Y, Greenberg J, Kremer JM, Kavanaugh A. Utilization trends of tumor necrosis
factor inhibitors among rheumatoid arthritis patients in United States Observational Cohort Study. J
Rheumatol 2009;36(8):1611-17.
21. Lee SJ, Hirsch JD, Terkeltaub R, Khanna D, Singh JA, Sarkin, Kavanaugh A. Perceptions of disease and
health related quality of life (HRQoL) among patients with gout. Rheumatology 2009; 48(5):582-86.
PHS 398/2590 (Rev. 06/09)
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Biographical Sketch Format Page
Program Director/Principal Investigator (Last, First, Middle):
Lee, Susan Jung-Ah
22. Lee SJ, Kremer J, Kavanaugh A, Consortium of Rheumatology Researchers of North America
(CORRONA). Treatment disparity related to race/ethnicity and education in rheumatoid arthritis: comment
on the article by Constantinescu et al. Arthritis Care Res 2009;61(8):1141-42.
23. Lee SJ, Chinen J, Kavanaugh A. Immunomodulator therapy: Monoclonal antibodies, fusion proteins,
cytokines, and immunoglobulins. J Allergy Clin Immunol 2010;125(2 Suppl2):S314-23.
24. Kavanaugh A, Lee, SJ, Weng HH, Chon Y, Huang XY, Lin SL. Patient-Derived Joint Counts Are a Potential
Alternative for Determining Disease Activity Score. J Rheumatol 2010;37:1035-41.
25. Sarkin AJ, Leevak AE, Shieh MM, Kavanaugh AF, Khanna D, Singh JA et al. Predictors of physician-rated
and patient-rated gout severity: gout impact scales improve assessment. J Eval Clin Pract 2010 (in press).
26. Hirsch JD, Terkeltaub R, Khanna D, Singh J, Sarkin A, Shieh M, Kavanaugh A, Lee SJ. Gout specific
quality of life and the association with gout characteristics. Patient Related Outcome Measures 2010;1:1-8.
27. Lee SJ, Ballow M. Monoclonal antibodies and fusion proteins and their complications: Targeting B cells in
autoimmune diseases. J Allergy Clin Immunol 2010;125:814-20.
28. Singh JA, Sarkin A, Shieh M, Khanna D, Terkeltaub, Lee SJ, Kavanaugh, A, Hirsch JD. Health Care
Utilization in Patients with Gout. Seminars Arth Rheum 2010. In Press.
Abstracts
1. Lee S, Kavanaugh A, Reed G, Abramson S, Kremer J, CORRONA. Race and Education Influence
Treatment and Disease Activity in Patients with Rheumatoid Arthritis (RA): Analysis from the CORRONA
Database. Arthritis Rheum 2004;50(9Suppl):S390.
2. Lee SJ, Reed G, Kavanaugh A, CORRONA. Treatment disparity related to race/ethnicity and education in
rheumatoid arthritis (RA) patients. Analysis from the CORRONA database. Arthritis Rheum
2005;52(9Suppl):S542.
3. Cassell S, Tutuncu Z, Lee SJ, Reed G, Kremer J, Pugliese D et al. Psoriatic arthritis (PsA) patients (Pts)
have different rate of adverse events (AE) than rheumatoid arthritis (RA) Pts on tumor necrosis factor
(TNF-I): analysis from the CORRONA database. Arthritis Rheum 2005;52(9Suppl):S211-12.
4. Greenberg JD, Abramson SB, Lee S, Rosenstein E, Reed G, K Hinkle et al. NSAID And COXIB
Prescribing By Rheumatologist For Patients With Gastrointestinal (GI) and Cardiovascular (CV) Risk In
2004-2005. Arthritis Rheum 2005;52(9Suppl):S664.
5. Tutuncu ZN , Boyle D, Lee S, Hallinan J, Weber J, Vasserot A, Breitmeyer James B, Kavanaugh A. A Dose
Escalation, Open-Label, Phase I/II Study Of AME-527, A Novel Anti-TNF Monoclonal Antibody (mAb) In
Subjects With Active Rheumatoid Arthritis (RA). Arthritis Rheum 2005;52(9Suppl):S346.
6. Lee SJ, Reed G, Soto L, Kremer J, Kavanaugh A. Persistence of clinical benefit in rheumatoid arthritis after
discontinuation of TNF-Inhibitors therapy: analysis from the CORRONA Database. Arthritis Rheum
2007;56(9Suppl):S311 [oral presentation].
7. Lee SJ, Saghafi O, Huang R, Skoczen S, Kavanaugh A, Lenert L. Novel approach to assess patient
derived measures in rheumatoid arthritis. Arthritis Rheum 2007;56(9Suppl):S708.
8. Lee SJ, Reed G, Kremer J, Kavanaugh A. Characteristics of rheumatoid arthritis (RA) patients starting
abatacept and rituximab. Arthritis Rheum 2009;50(10Suppl):S601.
D. Research Support: Principal investigator of several on-going pharmaceutical sponsored phase II-III clinical
trials on inflammatory arthritis including psoriatic arthritis, rheumatoid arthritis, lupus, and gout at UCSD Center
for Innovative Therapy.
PHS 398/2590 (Rev. 06/09)
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Biographical Sketch Format Page