Download CURRICULUM VITAE

Haihong Shen
CURRICULUM VITAE
October, 2007
Name:
Haihong Shen, Ph.D.
Affiliation:
Assistant Professor
Dept. Life Science
Gwangju Institute of Science and Technology
1 Oryoung Dong, Buk-Gu
Gwangju 500-712
Republic of Korea
Communication: Tel: (062) 970-2507
E-mail: [email protected]
Education Professional Background:
3/2001- 9/2007
Post-Doctoral Associate in the laboratory of Michael R. Green
Program in Gene Function and Expression, University of Massachusetts
Medical School, USA
3/1997 – 2/2001 Ph.D., Dept. of Biological Sciences, Korea Advanced Institute of Science
and Technology. Daejeon, Korea (Advisor: Changwon Kang)
Thesis: Characterization of T7 RNA polymerase elongation complex
9/1993 – 7/1996 M.S., in Cell Biophysics, Institute of Biophysics, Academia Sinica,
Beijing, P. R. China (Advisor: Jiin-Ju Chang)
Thesis: Pulsed electric field affects Ca2+ and cAMP in the embryonic
Brain cells
9/1982 – 7/1986 B.S., Dept. of Biological Sciences, Peking University, Beijing, P. R. China
Pre-MS Research Experiences:
8/1989 – 7/1993 Research Assistant in molecular biology, cancer biology, drug
development, pharmacology, and molecular immunology, Yanbian Cancer
Center, P. R. China
9/1986 – 7/1989 Research Assistant in biochemistry, immunochemistry, immunology, and
clinical molecular biology, Beijing General Hospital, P. R. China
Awards:
7/2004 – 6/2006 Charles King’s Trust Post-doctoral Fellowship, Medical Foundation, USA
3/1997 – 2/2001 Government Scholarship, Korea Advanced Institute of Science and
Technology
9/1993 – 7/1996 Government Scholarship, Institute of Biophysics, Academia Sinica
9/1982 – 7/1986 University Scholarship, Peking University
Haihong Shen
Teaching Experiences:
3/2001 – 3/2002
Part-time Teaching Assistant, Dept. of Biological Sciences, Korea
Advanced Institute of Science and Technology. Daejeon, Korea
Membership in Academic Societies:
1/2004 – present: The RNA Society
Publications:
1. Haihong Shen and Michael R. Green (2007) "RS domain-splicing signal interactions of
U12-type introns and during the second step of U2-type intron splicing." Nature
Structural and Molecular Biology, 14(7): 597-603
2. Haihong Shen and Michael R. Green (2006) "RS domains contact splicing signals and
promote splicing by a common mechanism in yeast through humans." Genes &
Development, 20(13):1755-1765 [highlighted in a Perspective in Genes & Development,
2006, 20(13):1679-1684]
3. E. Allen Sickmier, Katherine E. Frato, Haihong Shen, Shanthi R. Paranawithana, Michael
R. Green, and Clara L. Kielkopf (2006) "Structural basis for polypyrimidine tract
recognition by the essential pre-mRNA splicing factor U2AF65" Molecular Cell,
23(1):49-59
4. Claudia Ghigna, Silvia Giordano, Haihong Shen, Federica Benvenuto, Paolo Maria
Comoglio, Michael R. Green, Silvano Riva and Giuseppe Biamonti (2005) "Cell motility
is controlled by SF2/ASF through alternative splicing of the Ron protooncogene"
Molecular Cell, 20(6):881-890
5. Haihong Shen and Michael R. Green (2004) "A pathway of sequential arginine-serinedomain-splicing signal interactions during mammalian spliceosome assembly" Molecular
Cell, 16(3):363-373 [Highlighted on the cover of Molecular Cell, 2004, 16(3); Trends
Biochem Sci. 2005, 30(3):115-118; Nat Struct Mol Biol. 2005, 12(8):645-653]
6. Haihong Shen, Julie L. Kan, Claudia Ghigna and Michael R. Green (2003) “A single
polypyrimidine tract binding protein (PTB) binding site mediates splicing inhibition at
mouse IgM exons M1 and M2” RNA, 10(5):787-794
7. Haihong Shen, Julie L. Kan and Michael R. Green (2004) “Arginine-serine-rich domains
bound at splicing enhancers contact the branchpoint to promote pre-spliceosome
assembly” Molecular Cell, 13(3):367-376
8. Younghee Sohn, Haihong Shen, Changwon Kang (2003) “Stepwise walking and crosslinking of RNA with elongating T7 RNA polymerase” Methods Enzymol., 371:170-179
9. Haihong Shen and Changwon Kang (2001) “Two site contact of elongating transcripts to
phage T7 RNA polymerase at C-terminal regions” J. Biol. Chem., 276(6):4080-4084
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Haihong Shen
10. Haihong Shen and Jiin-Ju Chang (1996) “Effects of pulsed electric field on Ca2+ content
in embryonic brain cells. I” Acta Biophysica Sinica, 12(3):23-26
11. Haihong Shen and Jiin-Ju Chang (1996) “Effects of pulsed electric field on cAMP conte
nt in embryonic brain cells. II” Acta Biophysica Sinica, 12(2):16-19
References:
Michael R Green
Program in Gene Function and Expression
University of Massachusetts Medical School
Lazare Research Building, Room 628
364 Plantation Street
Worcester, MA 01605
508-856-5330 (office)
508-856-5473 (fax)
[email protected]
Juan Valcarcel
Center for Genomic Regulation
Passeig Maritim 37-49
08003 Barcelona
Spain
34-93-2240956 (office)
34-93-2240899 (fax)
[email protected]
Clara L. Kielkopf
Department of Biochemistry and Molecular Biology
Johns Hopkins University
Rm. W8708 BSPH
615 N. Wolfe St.
Baltimore, MD 21205
443-287-4546 (office)
410-995-2926 (fax)
[email protected]
Changwon Kang
Department of Biological Sciences
Korea Advanced Institute of Science and Technology (KAIST)
373-1 Guseong-dong, Yuseong-gu
Daejeon 305-701, Korea
82-42-869-2628 (office)
82-42-869-2682 (fax)
[email protected]
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