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Apoptotic cells promote macrophage survival by releasing
the antiapoptotic mediator sphingosine-1-phosphate
by Andreas Weigert, Axel M. Johann, Andreas von Knethen, Helmut Schmidt, Gerd
Geisslinger, and Bernhard Brüne
Blood
Volume 108(5):1635-1642
September 1, 2006
©2006 by American Society of Hematology
Apoptotic cells attenuate caspase-3 activation in murine and human macrophages.
Andreas Weigert et al. Blood 2006;108:1635-1642
©2006 by American Society of Hematology
Apoptotic cells attenuate macrophage apoptosis.
Andreas Weigert et al. Blood 2006;108:1635-1642
©2006 by American Society of Hematology
Macrophage protection caused by an apoptotic cell-derived soluble factor.
Andreas Weigert et al. Blood 2006;108:1635-1642
©2006 by American Society of Hematology
Protection of primary human macrophages by ACM is PI3K-, Ca2+-, and ERK1/2-dependent.
Andreas Weigert et al. Blood 2006;108:1635-1642
©2006 by American Society of Hematology
Sphingosine-1-phosphate conveys protection.
Andreas Weigert et al. Blood 2006;108:1635-1642
©2006 by American Society of Hematology
Measurement of S1P secretion by apoptotic cells.
Andreas Weigert et al. Blood 2006;108:1635-1642
©2006 by American Society of Hematology
Sphk2 expression in apoptotic cells contributes to the release of S1P.
Andreas Weigert et al. Blood 2006;108:1635-1642
©2006 by American Society of Hematology
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