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Detection of t(11;18)(q21;q21) by interphase fluorescence in situ hybridization using API2 and MLTspecific probes by Judith Dierlamm, Mathijs Baens, Margarita Stefanova-Ouzounova, Kristina Hinz, Iwona Wlodarska, Brigitte Maes, Anja Steyls, Ann Driessen, Gregor Verhoef, Philippe Gaulard, Anne Hagemeijer, Dieter Kurt Hossfeld, Christiane De Wolf-Peeters, and Peter Marynen Blood Volume 96(6):2215-2218 September 15, 2000 ©2000 by American Society of Hematology PAC contig spanning the chromosome 18 breakpoint of t(11;18)(q21;q21).PAC 57N9, which has been applied in the present interphase FISH assay, hybridizes telomerically to the breakpoint and is translocated to the derivative chromosome 11 resulting from t(11;1... Judith Dierlamm et al. Blood 2000;96:2215-2218 ©2000 by American Society of Hematology The structure of the API2 gene and the adjacent API1gene on chromosome 11q22. Judith Dierlamm et al. Blood 2000;96:2215-2218 ©2000 by American Society of Hematology Fluorescence in situ hybridization assay for the detection of t(11;18)(q21;q21) on metaphase chromosomes and interphase nuclei.(A) On the left side, the normal localization of PACs 166G16 and 59N7 can be seen. Judith Dierlamm et al. Blood 2000;96:2215-2218 ©2000 by American Society of Hematology
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